Protein Alignment mEFTu2 and TUFM

DIOPT Version :9

• Sequence 1: NP_610288.1
• Gene: mEFTu2 / 35681
• FlyBaseID: FBgn0033184
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_003312.3
• Gene: TUFM / 7284
• HGNCID: 12420
• Length: 455
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 208/411 - (50%)
• Similarity: 298/411 - (72%)
• Gaps: 4/411 - (0%)

  Fly    38 RLLATSADKNPAPGLRELPHCNVGTIGHVDHGKTTLTAAITRIQSQKGLAEYLSYDQIDRAPEEK 102
            |.||..|.|.   .:|:.||.||||||||||||||||||||:|.::.|.|::..|::||.||||:
Human    44 RGLAVEAKKT---YVRDKPHVNVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEER 105

  Fly   103 ARGITINACHIGYSTTERTYAHTDCPGHADYIKNMISGASQMDGAILVVAATDGQMPQTREHLLL 167
            ||||||||.|:.|||..|.||||||||||||:||||:|.:.:||.||||||.||.||||||||||
Human   106 ARGITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLL 170

  Fly   168 AKQVGIQRIIVFINKADLV-DQEVLELVEIEMREMLSDFGFDGVNSPVICGSALLALREDKSEFG 231
            |:|:|::.::|::||||.| |.|::||||:|:||:|::||:.|..:|||.||||.||.....|.|
Human   171 ARQIGVEHVVVYVNKADAVQDSEMVELVELEIRELLTEFGYKGEETPVIVGSALCALEGRDPELG 235

  Fly   232 VPSIEKLLEQCDSYIPTPQRDISSPFILPIDNAFTVPGRGTVVVGTIKRGTIPRNADADLLGFNQ 296
            :.|::|||:..|:|||.|.||:..||:||::..::||||||||.||::||.:.:..:.:|||.::
Human   236 LKSVQKLLDAVDTYIPVPARDLEKPFLLPVEAVYSVPGRGTVVTGTLERGILKKGDECELLGHSK 300

  Fly   297 NLKTSISDIQIFRKSVPQAQAGENVGALLRGIKISAVERGMLLCATGSEDISNHFEGSMYLLSRA 361
            |::|.::.|::|.||:.:|:||:|:|||:||:|...:.||:::...||.......|..:|:||:.
Human   301 NIRTVVTGIEMFHKSLERAEAGDNLGALVRGLKREDLRRGLVMVKPGSIKPHQKVEAQVYILSKE 365

  Fly   362 EGGRVKPMLSKYIQQLFSQTWNVPARIDIVPSEAMLMPGEHGQVRVTLLRKMVMTPGQAFTIREN 426
            ||||.||.:|.::..:||.||::..||.:.|.:.:.||||..:..:.|.:.|::..||.||:|:.
Human   366 EGGRHKPFVSHFMPVMFSLTWDMACRIILPPEKELAMPGEDLKFNLILRQPMILEKGQRFTLRDG 430

  Fly   427 GATVATGMVTQRLPSLDLPKN 447
            ..|:.||:||..|...:..||
Human   431 NRTIGTGLVTNTLAMTEEEKN 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu2	NP_610288.1	PRK00049	53..437	CDD:234596	199/384 (52%)
		EF_Tu	56..249	CDD:206671	123/193 (64%)
		EFTU_II	257..343	CDD:293898	36/85 (42%)
		mtEFTU_III	347..437	CDD:294005	33/89 (37%)
TUFM	NP_003312.3	SelB	50..444	CDD:332589	202/396 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0050
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S366
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D298219at33208
OrthoFinder	1	1.000	-	-		FOG0002097
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43721
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.870