Protein Alignment mEFTu2 and TUFM

DIOPT Version :10

• Sequence 1: NP_610288.1
• Gene: mEFTu2 / 35681
• FlyBaseID: FBgn0033184
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_003312.3
• Gene: TUFM / 7284
• HGNCID: 12420
• Length: 455
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 208/411 - (50%)
• Similarity: 298/411 - (72%)
• Gaps: 4/411 - (0%)

  Fly    38 RLLATSADKNPAPGLRELPHCNVGTIGHVDHGKTTLTAAITRIQSQKGLAEYLSYDQIDRAPEEK 102
            |.||..|.|.   .:|:.||.||||||||||||||||||||:|.::.|.|::..|::||.||||:
Human    44 RGLAVEAKKT---YVRDKPHVNVGTIGHVDHGKTTLTAAITKILAEGGGAKFKKYEEIDNAPEER 105

  Fly   103 ARGITINACHIGYSTTERTYAHTDCPGHADYIKNMISGASQMDGAILVVAATDGQMPQTREHLLL 167
            ||||||||.|:.|||..|.||||||||||||:||||:|.:.:||.||||||.||.||||||||||
Human   106 ARGITINAAHVEYSTAARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAANDGPMPQTREHLLL 170

  Fly   168 AKQVGIQRIIVFINKADLV-DQEVLELVEIEMREMLSDFGFDGVNSPVICGSALLALREDKSEFG 231
            |:|:|::.::|::||||.| |.|::||||:|:||:|::||:.|..:|||.||||.||.....|.|
Human   171 ARQIGVEHVVVYVNKADAVQDSEMVELVELEIRELLTEFGYKGEETPVIVGSALCALEGRDPELG 235

  Fly   232 VPSIEKLLEQCDSYIPTPQRDISSPFILPIDNAFTVPGRGTVVVGTIKRGTIPRNADADLLGFNQ 296
            :.|::|||:..|:|||.|.||:..||:||::..::||||||||.||::||.:.:..:.:|||.::
Human   236 LKSVQKLLDAVDTYIPVPARDLEKPFLLPVEAVYSVPGRGTVVTGTLERGILKKGDECELLGHSK 300

  Fly   297 NLKTSISDIQIFRKSVPQAQAGENVGALLRGIKISAVERGMLLCATGSEDISNHFEGSMYLLSRA 361
            |::|.::.|::|.||:.:|:||:|:|||:||:|...:.||:::...||.......|..:|:||:.
Human   301 NIRTVVTGIEMFHKSLERAEAGDNLGALVRGLKREDLRRGLVMVKPGSIKPHQKVEAQVYILSKE 365

  Fly   362 EGGRVKPMLSKYIQQLFSQTWNVPARIDIVPSEAMLMPGEHGQVRVTLLRKMVMTPGQAFTIREN 426
            ||||.||.:|.::..:||.||::..||.:.|.:.:.||||..:..:.|.:.|::..||.||:|:.
Human   366 EGGRHKPFVSHFMPVMFSLTWDMACRIILPPEKELAMPGEDLKFNLILRQPMILEKGQRFTLRDG 430

  Fly   427 GATVATGMVTQRLPSLDLPKN 447
            ..|:.||:||..|...:..||
Human   431 NRTIGTGLVTNTLAMTEEEKN 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu2	NP_610288.1	TufA	53..436	CDD:439820	198/383 (52%)
TUFM	NP_003312.3	TufA	50..444	CDD:439820	202/396 (51%)
		G1. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	67..74		6/6 (100%)
		G2. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	108..112		3/3 (100%)
		G3. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	129..132		2/2 (100%)
		G4. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	184..187		2/2 (100%)
		G5. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	222..224		1/1 (100%)