Protein Alignment mEFTu2 and mIF2

DIOPT Version :9

• Sequence 1: NP_610288.1
• Gene: mEFTu2 / 35681
• FlyBaseID: FBgn0033184
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_651621.2
• Gene: mIF2 / 43382
• FlyBaseID: FBgn0039588
• Length: 696
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 130/613 - (21%)
• Similarity: 211/613 - (34%)
• Gaps: 239/613 - (38%)

  Fly    16 LVRRISQALIGPGASQSRWTGTRLLATSADKNP-----------APGLREL--PHCNVGTI-GHV 66
            :::.|::.|   ||.      ||::||..:.|.           .|...||  |...|.|: |||
  Fly   116 IIQEIAKKL---GAK------TRVVATPEETNADEQKERDVAPRPPAAPELLQPRPPVVTVMGHV 171

  Fly    67 DHGKTTLTAAITRIQSQKGLAEYLSYDQIDRAPEEKARGITINACHIGYSTT-----ERTYAHTD 126
            |||||||      :.|.:|         .|.|..| |.|||   .|||..|.     ||. ...|
  Fly   172 DHGKTTL------LDSLRG---------ADVAAGE-AGGIT---QHIGAFTVTLENGERV-TFLD 216

  Fly   127 CPGHADYIKNMISGASQMDGAILVVAATDGQMPQTREHLLLAKQVGIQRIIVFINKADLVDQEVL 191
            .||||.:......||...|..:|||||.||.|.||||.:.|||:..:. |||.:||.|..:..:
  Fly   217 TPGHAAFSAMRARGAVATDIIVLVVAAEDGVMAQTREVIQLAKEAQVP-IIVALNKIDKPEANI- 279

  Fly   192 ELVEIEMREM---LSDFGFD----------GVN-----SPVICGSALLALREDKSEFGVPSIEKL 238
            |..:.|:.:|   |.:.|.|          |.|     ..|...:.|:.|:.|.:..    :|.:
  Fly   280 EKSKRELAQMGLALEEHGGDVQVIPISALKGTNLELLAEAVSTQATLMGLKADPTGL----VEGI 340

  Fly   239 LEQCDSYIPTPQRDISSPFILPIDNAFTVPGRG---TVVV--GTIKRGTI--------------- 283
            :.:                      :.|.|.||   |.:|  ||:::|::
  Fly   341 VVE----------------------SKTDPRRGKLSTAIVSRGTLRKGSVLLSGLAHAKVRGLFD 383

  Fly   284 ---------PRNADADLLGF-------------------------------NQNLKTSISDIQ-- 306
                     |.....::||:                               .:.:::|..:|:
  Fly   384 HNGQPLSEAPPGTPVEILGWRELPLAGDLILEVETEKKAHAVLKYREHESQQEKIESSSDEIRKK 448

  Fly   307 -------------------IFR-------KSVPQAQAGENVGALLRG------------------ 327
                               .||       |.|.:.:....|..:::|
  Fly   449 EEEHQAKYRAEREARRLAGRFRMRGGQRVKQVDENEGKPRVSVIIKGDVHGSVEAILDVLETYNS 513

  Fly   328 ---IKISAVERGMLLCATGSEDISNHFEGSMYLLSRAEGGRVKPMLSKYIQQLFSQTWNV----- 384
               .::..|..|:.....|..:::..|...:|..:      |:....|..:::..:::|:
  Fly   514 NESCRLDIVHYGVGNVTEGDLELAKAFHAIIYAFA------VETPQLKAAKEVNIRSYNIIYRLI 572

  Fly   385 ------------PARIDIVPSEAMLMPG---EHGQVRVTL----LRKMVMTPGQAFTIRENGATV 430
                        |..::.|..||.::..   ..|:..|.:    ..|.|:...|.|.:..:|..|
  Fly   573 DDLKEQLSSKLPPVEVEEVLGEANVLQNFLINEGRKEVPVAGCRCTKGVLKKAQKFRLLRDGEVV 637

  Fly   431 ATGMVTQRLPSLDLPKNKLS--KVFVDC 456
            ..|    .|.|:...||::.  |..|:|
  Fly   638 YDG----PLESMRHLKNEVDTIKKDVEC 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu2	NP_610288.1	PRK00049	53..437	CDD:234596	113/542 (21%)
		EF_Tu	56..249	CDD:206671	70/216 (32%)
		EFTU_II	257..343	CDD:293898	22/194 (11%)
		mtEFTU_III	347..437	CDD:294005	18/113 (16%)
mIF2	NP_651621.2	InfB	158..689	CDD:223606	118/562 (21%)
		IF2_eIF5B	163..327	CDD:206674	65/185 (35%)
		IF2_mtIF2_II	336..431	CDD:293903	13/120 (11%)
		IF-2	482..575	CDD:288813	10/98 (10%)
		mtIF2_IVc	593..680	CDD:293893	18/73 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464599
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840