DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mEFTu2 and waw

DIOPT Version :9

Sequence 1:	NP_610288.1	Gene:	mEFTu2 / 35681	FlyBaseID:	FBgn0033184	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_001027089.1	Gene:	waw / 3771960	FlyBaseID:	FBgn0024182	Length:	696	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	104/393 - (26%)
Similarity:	153/393 - (38%)	Gaps:	99/393 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RQCEAGLVRRIS--QALIGPGASQ-SRWTGTR----LLATSADKNPAPG----------LRELPH 57
            |...:.::|.||  ..|..||..: |.|...|    |:...:..|...|          |||..|
  Fly    29 RNVNSAMIRAISIRWLLQRPGDKRHSAWLVARSKSLLVRNLSTTNQVKGETEEPSQADLLREFAH 93

  Fly    58 C------NVGTIGHVDHGKTT-------LTAAITRIQSQKGLAEYLSYDQIDRAPEEKARGITIN 109
            .      |...|.||||||:|       ||.||.|...|        :..:|....|:.||||:.
  Fly    94 MPVERIRNFSIIAHVDHGKSTLADRLLELTGAIARNGGQ--------HQVLDNLQVERERGITVK 150

  Fly   110 ACHIGYSTTERTYAH---------TDCPGHADYIKNMISGASQMDGAILVVAATDGQMPQTREHL 165
            |     .|....:.|         .|.|||.|:...:....:..||.:|:|.|..|...||..:.
  Fly   151 A-----QTASIFHRHKGQLYLLNLIDTPGHVDFSNEVSRSLAACDGVVLLVDACHGVQAQTVANY 210

  Fly   166 LLAKQVGIQRIIVFINKADL----VDQEVLELVEIEMREMLSDFGFDGVNSPVICGSALLALRED 226
            .||||..: .::..:||.|:    .||...:|      ::|  ||.|  ...|:..||.|.
  Fly   211 HLAKQRQL-AVVPVLNKIDIKHANPDQVCQDL------KLL--FGID--PDEVLRVSAKLG---- 260

  Fly   227 KSEFGVPSIEKLLEQCDSYIPTPQRDISSPFILPIDNAFTVPGRGTVVVGTIKRGTIPRNADADL 291
                  ..:.::||:....:|.||....|.|...|.:::....||.:.:..:..|.:.:|.|.
  Fly   261 ------TGVSEVLERVIETVPPPQVQRDSDFRALIFDSWFDKYRGALNLIYVLNGKLEQNQDI-- 317

  Fly   292 LGFNQNLKT----SISDIQIFRKS---VPQAQAGENVGAL---LRGIKISAVE-----RGMLLCA 341
                |:|.|    |:..|.:.|.:   ||...||: ||.:   :|..|.|.|.     :...:.|
  Fly   318 ----QSLATKKVYSVKSISVLRPAECPVPDVSAGQ-VGLIACNMRNSKESIVGDTIHLKNQAVAA 377

  Fly   342 TGS 344
            .||
  Fly   378 AGS 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu2	NP_610288.1	PRK00049	53..437	CDD:234596	90/333 (27%)
		EF_Tu	56..249	CDD:206671	59/218 (27%)
		EFTU_II	257..343	CDD:293898	24/100 (24%)
		mtEFTU_III	347..437	CDD:294005
waw	NP_001027089.1	PRK05433	94..695	CDD:235462	87/328 (27%)
		LepA	100..277	CDD:206677	58/210 (28%)
		EF4_II	285..370	CDD:293900	23/91 (25%)
		EF4_III	386..461	CDD:293917
		lepA_C	502..581	CDD:239680
		LepA_C	589..695	CDD:283959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464600
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840