DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mEFTu2 and eef1a1a

DIOPT Version :9

Sequence 1:	NP_610288.1	Gene:	mEFTu2 / 35681	FlyBaseID:	FBgn0033184	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_956303.1	Gene:	eef1a1a / 336334	ZFINID:	ZDB-GENE-030131-8278	Length:	462	Species:	Danio rerio

Alignment Length:	464	Identity:	115/464 - (24%)
Similarity:	200/464 - (43%)	Gaps:	109/464 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 RELPHCNVGTIGHVDHGKTTLTA------------AITRIQSQ-----KGLAEYLSYDQIDRAPE 100
            :|..|.|:..|||||.||:|.|.            .|.:.:.:     ||..:|...  :|:...
Zfish     3 KEKLHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWV--LDKLKA 65

  Fly   101 EKARGITINACHIGYSTTERTYAHTDCPGHADYIKNMISGASQMDGAILVVAATDGQMP------ 159
            |:.|||||:.....:.|::......|.|||.|:|||||:|.||.|.|:|:|||..|:..
Zfish    66 ERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKN 130

  Fly   160 -QTREHLLLAKQVGIQRIIVFINKADLVD--------QEVLELVEIEMREMLSDFGFDGVNSPVI 215
             |||||.|||..:|::::||.:||.|..:        :|:::.|...::::       |.|...:
Zfish   131 GQTREHALLAYTLGVKQLIVGVNKMDSTEPSYSQKRYEEIVKEVSTYIKKI-------GYNPDTV 188

  Fly   216 C--------GSALLALREDKSEF---------GVPSIEKLLEQCDSYIPTPQRDISSPFILPIDN 263
            .        |..:|....:.|.|         |..:...|||..|:..| |.|....|..||:.:
Zfish   189 AFVPISGWNGDNMLEASPNMSWFKGWKITRKEGNAAGTTLLEALDAIQP-PTRPTDKPLRLPLQD 252

  Fly   264 AFTVPGRGTVVVGTIKRGTIPRNADADLLGFNQ-NLKTSISDIQIFRKSVPQAQAGENVGALLRG 327
            .:.:.|.|||.||.::.|.:....   ::.|.. |:.|.:..:::..:::.:|..|:|||..::.
Zfish   253 VYKIGGIGTVPVGRVETGLLKPGM---VVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKN 314

  Fly   328 IKISAVERGMLLCATGSEDISN-------HFEGSMYLLSRAEGGRVK----PMLSKYIQQLFSQT 381
            :.:..:.||.:     :.|..|       :|...:.:|:..  |::.    |:|..:...:..:.
Zfish   315 VSVKDIRRGNV-----AGDSKNDPPQEAANFTAQVIILNHP--GQISAGYAPVLDCHTAHIACKF 372

  Fly   382 WNVPARID------IVPSEAMLMPGEHGQVRVTLLRKMVMTPGQ--------------AFTIREN 426
            ..:..:||      :..:...|..|:...|.        |.||:              .|.:|:.
Zfish   373 AELKEKIDRRSGKKLEDNPKSLKSGDAAIVE--------MIPGKPMCVESFSEYPPLGRFAVRDM 429

  Fly   427 GATVATGMV 435
            ..|||.|::
Zfish   430 RQTVAVGVI 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu2	NP_610288.1	PRK00049	53..437	CDD:234596	115/464 (25%)
		EF_Tu	56..249	CDD:206671	71/241 (29%)
		EFTU_II	257..343	CDD:293898	19/86 (22%)
		mtEFTU_III	347..437	CDD:294005	20/120 (17%)
eef1a1a	NP_956303.1	PTZ00141	1..460	CDD:185474	115/464 (25%)
		EF1_alpha	9..238	CDD:206670	70/238 (29%)
		EF1_alpha_II	242..332	CDD:293894	21/97 (22%)
		EF1_alpha_III	336..438	CDD:294004	19/111 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840