DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mEFTu2 and eef1a1l1

DIOPT Version :9

Sequence 1:	NP_610288.1	Gene:	mEFTu2 / 35681	FlyBaseID:	FBgn0033184	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_571338.1	Gene:	eef1a1l1 / 30516	ZFINID:	ZDB-GENE-990415-52	Length:	462	Species:	Danio rerio

Alignment Length:	461	Identity:	116/461 - (25%)
Similarity:	197/461 - (42%)	Gaps:	103/461 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 RELPHCNVGTIGHVDHGKTTLTA------------AITRIQSQ-----KGLAEYLSYDQIDRAPE 100
            :|..|.|:..|||||.||:|.|.            .|.:.:.:     ||..:|...  :|:...
Zfish     3 KEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWV--LDKLKA 65

  Fly   101 EKARGITINACHIGYSTTERTYAHTDCPGHADYIKNMISGASQMDGAILVVAATDGQMP------ 159
            |:.|||||:.....:.|::......|.|||.|:|||||:|.||.|.|:|:||...|:..
Zfish    66 ERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAGGVGEFEAGISKN 130

  Fly   160 -QTREHLLLAKQVGIQRIIVFINKADLVD----QEVLELVEIEMREMLSDFGFDGVNSPVI---- 215
             |||||.|||..:|::::||.:||.|..:    |...|.:..|:...:...|::..:...:
Zfish   131 GQTREHALLAFTLGVKQLIVGVNKMDSTEPPYSQARFEEITKEVSAYIKKIGYNPASVAFVPISG 195

  Fly   216 -CGSALLALREDKSEFGVPSIEK---------LLEQCDSYIPTPQRDISSPFILPIDNAFTVPGR 270
             .|..:|....:...|....||:         ||:..|:.:| |.|....|..||:.:.:.:.|.
Zfish   196 WHGDNMLEASSNMGWFKGWKIERKEGNASGTTLLDALDAILP-PSRPTDKPLRLPLQDVYKIGGI 259

  Fly   271 GTVVV-----GTIKRGTIPRNADADLLGFNQNLKTSISDIQIFRKSVPQAQAGENVGALLRGIKI 330
            |||.|     |.:|.|.:...|.|       |:.|.:..:::..:|:.:|..|:|||..::.:.:
Zfish   260 GTVPVGRVETGVLKPGMVVTFAPA-------NVTTEVKSVEMHHESLTEATPGDNVGFNVKNVSV 317

  Fly   331 SAVERGMLLCATGSEDISN-------HFEGSMYLLSRAEGGRVK----PMLSKYIQQLFSQTWNV 384
            ..:.||.:     :.|..|       :|...:.:|:..  |::.    |:|..:...:..:...:
Zfish   318 KDIRRGNV-----AGDSKNDPPMEAANFNAQVIILNHP--GQISQGYAPVLDCHTAHIACKFAEL 375

  Fly   385 PARID------IVPSEAMLMPGEHGQVRVTLLRKMVMTPGQ--------------AFTIRENGAT 429
            ..:||      :..:...|..|:...|.        |.||:              .|.:|:...|
Zfish   376 KEKIDRRSGKKLEDNPKALKSGDAAIVE--------MVPGKPMCVESFSTYPPLGRFAVRDMRQT 432

  Fly   430 VATGMV 435
            ||.|::
Zfish   433 VAVGVI 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu2	NP_610288.1	PRK00049	53..437	CDD:234596	116/461 (25%)
		EF_Tu	56..249	CDD:206671	69/234 (29%)
		EFTU_II	257..343	CDD:293898	22/90 (24%)
		mtEFTU_III	347..437	CDD:294005	20/120 (17%)
eef1a1l1	NP_571338.1	PTZ00141	1..460	CDD:185474	116/461 (25%)
		G1. /evidence=ECO:0000250	14..21		5/6 (83%)
		G2. /evidence=ECO:0000250	70..74		3/3 (100%)
		G3. /evidence=ECO:0000250	91..94		1/2 (50%)
		G4. /evidence=ECO:0000250	153..156		2/2 (100%)
		G5. /evidence=ECO:0000250	194..196		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592515
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840