Protein Alignment mEFTu2 and EIF2S3B

DIOPT Version :10

• Sequence 1: NP_610288.1
• Gene: mEFTu2 / 35681
• FlyBaseID: FBgn0033184
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_001344663.1
• Gene: EIF2S3B / 255308
• HGNCID: 43863
• Length: 472
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 97/381 - (25%)
• Similarity: 151/381 - (39%)
• Gaps: 108/381 - (28%)

  Fly    59 NVGTIGHVDHGKTTLTAAITRIQSQKGLAEYLSYDQIDRAPEEKARGITINACHIGYSTTE---- 119
            |:||||||.|||:|:..||:.:.:.             |...|..|.|||.   :||:..:
Human    43 NIGTIGHVAHGKSTVVKAISGVHTV-------------RFKNELERNITIK---LGYANAKIYQL 91

  Fly   120 ------------------------------------RTYAHTDCPGHADYIKNMISGASQMDGAI 148
                                                |..:..|||||...:..|::||:.||.|:
Human    92 DDPSCPRPECYRSCGSSMPDEFPTDIPGTKGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAAL 156

  Fly   149 LVVAATDG-QMPQTREHLLLAKQVGIQRIIVFINKADLVDQEVLELVEIEMREMLSDF--GFDGV 210
            |::|..:. ..|||.|||...:.:.::.|::..||.|||.:...:    |..|.:..|  |....
Human   157 LLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKERQAK----EQYEQILAFVQGTVAE 217

  Fly   211 NSPVICGSALLALREDKSEFGVPSIEKLLEQCDSYIPTPQRDISSPFILPIDNAFTV--PG---- 269
            .:|:|..||.|..          :||.:.|.....||.|.||.:|...|.:..:|.|  ||
Human   218 GAPIIPISAQLKY----------NIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVD 272

  Fly   270 --RGTVVVGTIKRGTIPRNADADLLGFNQNLKTSISDIQIFRKSV--------------PQAQAG 318
              :|.|..|:|.:|.:....:.::   ...:.:..|:.::..||:              ..|..|
Human   273 DLKGGVAGGSILKGVLKVGQETEV---RPGIVSKDSEGKLMCKSIFSKIVSLFAEHNDLQYAAPG 334

  Fly   319 ENVGALLRGIKIS----AVER--GMLLCATGS-EDISNHFEGSMYLLSRAEGGRVK 367
            ..:|.   |.||.    ..:|  |.:|.|.|: .:|....|.|.:||.|..|.|.:
Human   335 GLIGV---GTKIDPTLCRADRMVGQILGAVGALPEIFTELEISYFLLRRLLGVRTE 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu2	NP_610288.1	TufA	53..436	CDD:439820	97/381 (25%)
EIF2S3B	NP_001344663.1	PTZ00327	13..466	CDD:240362	97/381 (25%)