Protein Alignment didum and ninaC

DIOPT Version :10

• Sequence 1: NP_724569.1
• Gene: didum / 35680
• FlyBaseID: FBgn0261397
• Length: 1800
• Species: Drosophila melanogaster
• Sequence 2: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Alignment Length: 1313
• Identity: 305/1313 - (23%)
• Similarity: 529/1313 - (40%)
• Gaps: 285/1313 - (21%)

  Fly    19 ADLVWESATLEESYRKGAGFLKICTDSGKLKEVKLKAD---GSDLPPLRNPAILVGQNDLTTLSY 80
            |:::..|..::..|::...|:    |.|.:|....|.:   ..||..|.||   |.:|
  Fly   297 AEMLELSRDVKTLYKEPELFV----DRGYVKRFDEKPEKMYPEDLAALENP---VDEN------- 347

  Fly    81 LHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMPLYGPSIIRAYRGHAMGDLEPHIFALAE 145
                 ::.:||.|....: .|::.|.||:::|.......:.......||..:..:.:||||::|:
  Fly   348 -----IIESLRHRILMGE-SYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPHIFSVAD 406

  Fly   146 EAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVG-GSESET-QVERKVLASSPIMEAFG 208
            .||..:........|::||||.:||:.:|:..:::...:| |:...| :||..:.|...::
  Fly   407 IAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSIKAILMLV---- 467

  Fly   209 NAKTTRNDNSSR--------FGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQGERNYHI 265
            ||.|..|::|:|        |||..|           :.||..:.|:|||.||......:.|:||
  Fly   468 NAGTPVNNDSTRCVLQYCLTFGKTGK-----------MSGAVFNMYMLEKLRVATTDGTQHNFHI 521

  Fly   266 ---FYQLCAARSKYPELVLDHQDKFQFLNMGGAPEI----------ERVSDAEQFNETVQAMTVL 317
               ||.....:::..|..|.....:::|.:  .||:          :...:.|::.|....:..:
  Fly   522 FYYFYDFINQQNQLKEYNLKADRNYRYLRV--PPEVPPSKLKYRRDDPEGNVERYREFENILRDI 584

  Fly   318 GFSIQQIADIVKILAGILHLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQITADLLRVSADDLR 382
            .|:.:|:..:.|:||.||::|||    :|.:..:..:.::.||      :...|:||||   |.:
  Fly   585 DFNHKQLETVRKVLAAILNIGNI----RFRQNGKYAEVENTDI------VSRIAELLRV---DEK 636

  Fly   383 RWLLMRKIESVNEYVLIPNSI--------EAAQAARDALAKHIYAKLFQYIVGVLNKSLNNGSKQ 439
            :::.     |:..::::...|        |.|:.||||:|..:|::|..:|:..:|  :|....:
  Fly   637 KFMW-----SLTNFIMVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRIN--MNMSFPR 694

  Fly   440 CSF-----IGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDF 499
            ..|     |.:.|::|||.|..|..||..||..||::|..:||.:|..|..|...|.|....::|
  Fly   695 AVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNF 759

  Fly   500 YDNQPCID-LIESRLGVLDLLDEECRMPKGSDESWAGKLI--GKCNKFPHFEKPRFGTTSFFIKH 561
            |||:..:| |:....|:..::|:..|..:..|      ||  ....|...|.| :...|...:.|
  Fly   760 YDNKTALDNLLTKPDGLFYIIDDASRSCQDQD------LIMDRVSEKHSQFVK-KHTATEISVAH 817

  Fly   562 FSDTVEYDVNGFLEKNRDTVSKELTQV----LSESNM-----SLAKQ---VMTLEEIDTLCVDSA 614
            ::..:.||...|.:.|||.|..|:.:.    |.||.|     .|.|.   .|..|.:........
  Fly   818 YTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESER 882

  Fly   615 KSSTLGGRVVISAGRKQQGNDTRRRVVPSKQHRKTVGSQFQESLASLISTLHATT---PHYVRCI 676
            ||..|.   .:|||...|.|:.|           |:.:.|:.:..:|:..|....   .|:||||
  Fly   883 KSYALN---TLSAGCISQVNNLR-----------TLAANFRFTCLTLLKMLSQNANLGVHFVRCI 933

  Fly   677 KPNDDKVAFKWETAKIIQQLRACGVLETVRISAAGFPSRWLYPDFYMRYQLLVYRSKLDKNDMKL 741
            :.:.:.....:.:..:.||::|.|||:||.....||.||..:.:|..|||.|.:.........|.
  Fly   934 RADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDEPVEMTKD 998

  Fly   742 SCRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRR-----Q 801
            :||.:.::  ...:.:..|.|::|.|.....||.:: ..|:.|.:..|||::|..:.|:     :
  Fly   999 NCRLLFLR--LKMEGWALGKTKVFLRYYNDEFLARL-YELQVKKVIKVQSMMRALLARKRVKGGK 1060

  Fly   802 FLRIQK--------VINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSIS 858
            ..::.|        ..:.|||..||:..|.|...:...::|.:....|                .
  Fly  1061 VFKLGKKGPEHHDVAASKIQKAFRGFRDRVRLPPLVNEKSGQLNENTA----------------D 1109

  Fly   859 GIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRR-RNIIICQAAI--RRFLARR- 919
            .|:.:|:....::.|..:. ||||.:.|.||..:.....|.:|. ..:..|..|:  .|...|.
  Fly  1110 FIRPFAKKWREKSIFQVLL-HYRAARFQDFVNLSQQVHIYNQRMVAGLNKCTRAVPFERINMREV 1173

  Fly   920 ----------KFKRMKAEAKTISHMENKYM----------GLENKIISMQQRIDELNRDNSNLKH 964
                      ..|:|......|...:.:||          ...|::::.....||  ..:|.|:.
  Fly  1174 NSSQLGPLPVPIKKMPFRLDQIPFYDTQYMVDPANSISRQAFPNQLLTQHMEDDE--PWDSPLQR 1236

  Fly   965 KTSEISVLKMKLELKKTLEAEFKNVKAACQDK-DKLIEALN----------KQLEAERDEKMQL- 1017
            ..|..|........||         :.|||.. |::.|:.|          :||   |..:||:
  Fly  1237 NPSMTSCALTYNAYKK---------EQACQTNWDRMGESDNIYNQGYFRDPQQL---RRNQMQMN 1289

  Fly  1018 LEENGHAQEEWIS--QKQTWRQENEELRRQIDEIIDMA----------------KNAEVNQRNQE 1064
            :....:|...:.|  ..|.|.......||  :.:...|                .|....|||.:
  Fly  1290 MNAYNNAYNSYNSNYNNQNWGVHRSGSRR--NSLKGYAAPPPPPPPMPSSNYYRNNPNQQQRNYQ 1352

  Fly  1065 DRM-------LAEIDNRELNEAYQRAIKDKEVIENENFMLKEELSRLT------AGSFSLHARKA 1116
            .|.       :.|:.|...||.        :..|:..|..|..|.:..      ..::..:.|:.
  Fly  1353 QRSSYPPSDPVRELQNMARNEG--------DNSEDPPFNFKAMLRKTNYPRGSETNTYDFNNRRG 1409

  Fly  1117 SNASSQN--------------EDDVGYASAKNTLDIN-------RPPDL----LSKNYSYNDSTS 1156
            |::..|:              :||.||.|:.....::       |.|.|    .|...|:.||.:
  Fly  1410 SDSGDQHTFQPPKLRSTGRRYQDDEGYNSSSGNYGVSRKFGQQQRAPTLRQSPASVGRSFEDSNA 1474

  Fly  1157 -LVVKLRSILEEE 1168
             ...:..|.:|||
  Fly  1475 RSFEEAGSYVEEE 1487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
didum	NP_724569.1	MYSc_Myo5	84..767	CDD:276831	190/736 (26%)
		IQ	900..922	CDD:197470	5/35 (14%)
		SMC_prok_B	<942..1365	CDD:274008	59/296 (20%)
		Myo5_CBD	1424..1792	CDD:271254
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	191/748 (26%)