Protein Alignment didum and Iqcb1

DIOPT Version :10

• Sequence 1: NP_724569.1
• Gene: didum / 35680
• FlyBaseID: FBgn0261397
• Length: 1800
• Species: Drosophila melanogaster
• Sequence 2: NP_001424691.1
• Gene: Iqcb1 / 303915
• RGDID: 1310069
• Length: 598
• Species: Rattus norvegicus
• Alignment Length: 696
• Identity: 122/696 - (17%)
• Similarity: 254/696 - (36%)
• Gaps: 227/696 - (32%)

  Fly   429 LNKSLNN---GSKQCSFIGVLDIYGFETFEVNSFEQFCINYANE-------------KLQQQFNQ 477
            |.:.:||   ||.:...: ..|||.::..      |:|:...::             :|.|..:.
  Rat    32 LKEIINNTPLGSSELKKV-KQDIYCYDLI------QYCLLVLSQDSSRIQGGWSTISQLTQILSH 89

  Fly   478 HVFKLEQ----EEYLKEGITWTMIDFYDNQPCIDLIESRLGVLDLLDEEC--RMPKGSDESWAGK 536
            ....||.    ||:.||.:.....:|.       ::..||       :.|  ...||.::
  Rat    90 CCVGLEPGEDGEEFYKELLPSAAENFL-------VLGRRL-------QTCFINATKGEEQ----- 135

  Fly   537 LIGKCNKFPHFEKPRFGTTSFFIKHFSDTVEYDVNGFLEKNRDTV-SKELTQVLSESNMSLAKQV 600
                 :|..|           |.:..:|::.:.:.|.::..::.: |.....:|...|:.:...|
  Rat   136 -----DKLLH-----------FFQIVTDSLFWLLGGHIQLIQNVLQSDHFLHLLQTDNVQIGATV 184

  Fly   601 MTLEEIDTLCVDSAKSSTLGGRVVISAGRKQQGNDTRRRVVPSKQHRKTVGSQFQESLASLIST- 664
            |||.: :.|.::|.....:.|                          |.:.|...|.|..|:||
  Rat   185 MTLLQ-NILQINSGNLLKIEG--------------------------KALHSILDEILFKLLSTP 222

  Fly   665 ---LHATTPHYVRCIKPNDDKVAFKWETAKIIQQLRACGVLETVRISAAGFPSRWLYPDFYMRYQ 726
               :.:|....:..:..:..::.       |:.:|.||                         |:
  Rat   223 SPVIRSTATKLLLVLAESHQEIL-------ILLRLSAC-------------------------YK 255

  Fly   727 LLVYRSKLDKNDMKLSCRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFL------EQVRANLRKKY 785
            .|  ||.|:|.:..                     |:......|:..|      ::|......|.
  Rat   256 GL--RSLLNKQETL---------------------TEFSRELRQLVDLLTPKIQQEVEEQKLHKA 297

  Fly   786 ITIVQSVVRRFVYRRQFLRIQKVINGIQ-----KHARGYLARERTQKMREARAGLILSKYARGWL 845
            ..::|:..:.|..|::..::...:..:|     |..:..|...|.::..:.|..|.|.|
  Rat   298 ACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRAKRTKMLLELNRQKEEEDLRLRLQLQK------ 356

  Fly   846 CRRRYLRL-RHS-ISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNI--- 905
              :|.:|| |.| :|.::....|.:  .|::...:...|:.||:..||...|:.::::|.::
  Rat   357 --QRAMRLSRESRLSMLEIIHPGQV--EKYNREIEEKSALTIQKHWRGYRERKNFRQQRPSLTEY 417

  Fly   906 ---IICQAAIRRFLAR-RKFKRMKAEAKTISHMENKYMGLEN----KIISMQQRIDELNRDNSNL 962
               :..|.|:.:|||: ||.|::.|          .:.||:.    :.:.::|::|:..:
  Rat   418 KAAVTLQRAVLKFLAKCRKKKKLFA----------SWHGLQELTDARRVELKQQVDDYVK----- 467

  Fly   963 KH---KTSEISVLKMKLELKKTLEAEFKNVKAACQDKDKLIEALNKQLEAERDEKMQ---LLEEN 1021
            :|   :.|:::..::..:.::.|:..|.. :|..:...:..|||..|:....::.|:   |.|..
  Rat   468 RHPGSQMSDVASRELHAQAQERLQHYFMG-RAIEERAQQHREALMAQISTNIEQLMKAPSLKEAE 531

  Fly  1022 GHAQEEWISQ--------KQT------------WRQENEELRRQID 1047
            |...|:::|:        ||.            |::..||...::|
  Rat   532 GKEPEQFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEEPGDEMD 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
didum	NP_724569.1	MYSc_Myo5	84..767	CDD:276831	58/364 (16%)
		IQ	900..922	CDD:197470	8/28 (29%)
		SMC_prok_B	<942..1365	CDD:274008	23/136 (17%)
		Myo5_CBD	1424..1792	CDD:271254
Iqcb1	NP_001424691.1	None