DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment didum and Rasip1

DIOPT Version :9

Sequence 1:	NP_724569.1	Gene:	didum / 35680	FlyBaseID:	FBgn0261397	Length:	1800	Species:	Drosophila melanogaster
Sequence 2:	XP_006229092.1	Gene:	Rasip1 / 292912	RGDID:	1305291	Length:	960	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	81/368 - (22%)
Similarity:	137/368 - (37%)	Gaps:	87/368 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1417 LMKFHSSDLDKILQRLLSALTPRTVVGLLPGF-PAYLIFMCIRYTDLTNADDDVRELLSKFVIQI 1480
            :::|...:.:.:|..::.|..  :..|.||.. ||.|:.:|::::........:..||.:....|
  Rat   537 VLRFRPREEEALLGEIVRAAA--SGAGDLPPLGPATLLALCVQHSARELELGHLPRLLGRLARLI 599

  Fly  1481 KKM---------HRTP--HP--------------IENR--VIWLVNSITLLNLMKQYGDVDEYVK 1518
            |:.         .|.|  ||              :|.|  ::|:.|:..||:.      |.|.|
  Rat   600 KEAVWEKIKEIGDRQPENHPEGVPEVPLTPEAVSVELRPLILWMANTTELLSF------VQEKV- 657

  Fly  1519 FNTEKQNQQ-------QLKN-FNLFEYRRVILD-LIVNLYQALIMQIQGLLDPKIVPAILNNDEI 1574
            ...||:..|       ||.| ..|.:....:|| :|:..:|..:..:...| ...:||:|:::..
  Rat   658 LEMEKEADQEGLSSDPQLCNDLELCDEALALLDEVIMCTFQQSVYYLTKTL-YSTLPALLDSNPF 721

  Fly  1575 QRGRQAHGMRSRATSIGASSSPEHGGGPAWKQLIGQLEHFYKQFQHFGLDNCYAEQIFHQLLYFI 1639
            ..|.:..|..:...::.....|..|...|..:|..|.|          |......|.|..|.:|.
  Rat   722 TAGAELPGPGAELEAMPPGLRPTLGVFQAALELTSQCE----------LHPDLVSQTFGYLFFFS 776

  Fly  1640 CAVALNCLMLRGD---ICMWETGMIIRYNIGCIEDWVRSKKMSNDVLTALAPLNQVSQLLQSRKS 1701
            .|..||.||.||.   ...|...:.||.|:..:.||::...: .|:.|..           .||.
  Rat   777 NASLLNSLMERGQGRPFYQWSRAVQIRTNLDLVLDWLQGAGL-GDIATEF-----------FRKL 829

  Fly  1702 EQDVQTICDLCTS---------------LSTAQVLKVMKSYKL 1729
            ...|..:|...||               |:.||:..::..|:|
  Rat   830 SIAVNLLCVPRTSLLKASWSSLRTDYPTLTPAQLHHLLSHYQL 872

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
didum	NP_724569.1	MYSc	65..778	CDD:214580
		MYSc_Myo5	84..767	CDD:276831
		IQ	900..922	CDD:197470
		GBP_C	<971..1086	CDD:303769
		coiled coil	1049..1068	CDD:293879
		coiled coil	1077..1086	CDD:293879
		JAKMIP_CC3	<1190..1299	CDD:292653
		Myo5_CBD	1424..1792	CDD:271254	80/361 (22%)
Rasip1	XP_006229092.1	Ubiquitin_like_fold	130..249	CDD:421700
Rasip1	XP_006229092.1	Myo5p-like_CBD_Rasip1	544..910	CDD:271256	80/361 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900