|
Fly 14 IWVPHADLVWESATLEESYRKGAGFLKICTDSGKLKEVKLKADGSDLPPLRNPAILVGQNDLTTL 78
:|||.....:|:|:::| .||...:....::|| |:.....|:..: ||.......|:..|
Rat 36 VWVPSEKQGFEAASIKE--EKGDEVVVELVENGK----KVTVGKDDIQKM-NPPKFSKVEDMAEL 93
Fly 79 SYLHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMPLYGPSIIRAYRGHAMGDLEPHIFAL 143
:.|:|..||||||.|:.. .:||||.|:..|.:|||..:|:|...|:..|:|....::.|||:|:
Rat 94 TCLNEASVLHNLRERYFS-GLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAI 157
Fly 144 AEEAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVGGS------ESETQ--------VE 194
|:.||..:.::..:.||:.:||||||||.:.|..::|.|.|..| .|.|| :|
Rat 158 ADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDSSITQGPSFAYGELE 222
Fly 195 RKVLASSPIMEAFGNAKTTRNDNSSRFGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQG 259
:::|.::||:||||||||.:||||||||||.::.| :..| ::.||.:.||||||||.:.||:.
Rat 223 KQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF-DVTG--YIVGANIETYLLEKSRAIRQARD 284
Fly 260 ERNYHIFYQLCA-ARSKY-PELVLDHQDKFQFLNMGGAPEIERVSDAEQFNETVQAMTVLGFSIQ 322
||.:||||.|.| |:.|. .:|:|:..:.:.||:.|..| |....|.|.|.||::||:::|||.:
Rat 285 ERTFHIFYYLIAGAKEKMRNDLLLESFNSYTFLSNGFVP-IPAAQDDEMFQETLEAMSIMGFSEE 348
Fly 323 QIADIVKILAGILHLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQITADLLRVSADDLRRWLLM 387
:...|:|:::.:|.|||| |.|| |.::|...:..|.. .|....|:.::..|..|.:|.
Rat 349 EQLAILKVVSSVLQLGNI-VFKK------ERNTDQASMPDNTA-AQKVCHLVGINVTDFTRAILT 405
Fly 388 RKIESVNEYVLIPNSIEAAQAARDALAKHIYAKLFQYIVGVLNKSLNNGSKQ-CSFIGVLDIYGF 451
.:|:...:.|....:.|.|..|.:||||..|.:||::|:..:||:|:...:| .||:|:|||.||
Rat 406 PRIKVGRDVVQKAQTKEQADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGF 470
Fly 452 ETFEVNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDF-YDNQPCIDLIE---SR 512
|.||||||||.||||.||||||.||..:|.||||||.:|||.|..||| .|.||||:||| :.
Rat 471 EIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNP 535
Fly 513 LGVLDLLDEECRMPKGSDESWAGKLIGKCNKFPHFEKPR--FGTTSFFIKHFSDTVEYDVNGFLE 575
.|||.||||||..||.:|:|:..||..:....|.|:||: ...|.|.|.|::..|:|:.:.:|.
Rat 536 PGVLALLDEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 600
Fly 576 KNRDTVSKELTQVLSESNMSLAKQVMTL-EEIDTLCVDSAKSSTLGGRVVISAGRKQQGNDTRRR 639
||.|.::..:|.:| |.|..|.|..| :::| |:| |..|....|...
Rat 601 KNMDPLNDNVTSLL---NASSDKFVADLWKDVD--------------RIV---GLDQMAKMTESS 645
Fly 640 VVPSKQHRK----TVGSQFQESLASLISTLHATTPHYVRCIKPNDDKVAFKWETAKIIQQLRACG 700
:..:.:.:| |||..::|.|..|::||..|||::||||.||.:|.:.|.:...:::|||..|
Rat 646 LPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNG 710
Fly 701 VLETVRISAAGFPSRWLYPDFYMRYQLLVYRSKLDKN--DMKLSCRNIVMKWIQDEDKYRFGNTQ 763
|||.:||...|||:|.::.:|..||::|. .:.:.|. |.|.:|..::.....|.:.||.|.::
Rat 711 VLEGIRICRQGFPNRIVFQEFRQRYEILA-ANAIPKGFMDGKQACILMIKALELDPNLYRIGQSK 774
Fly 764 IFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARER-TQK 827
||||.|.:|.||:.|. |:|..||...|...||||||:. |::
Rat 775 IFFRTGVLAHLEEERD-----------------------LKITDVIMAFQAMCRGYLARKAFTKR 816
Fly 828 MREARAGLILSKYARGWLCRR--RYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVR 890
.::..|..::.:....:|..| ::.||...:..:....| ...:..|..:..:.:: :|..:
Rat 817 QQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTR---QEEEMQAKEEEMQKIK-ERQQK 877
Fly 891 GALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMEN-------KYMGLENKIISM 948
.....:..::|. .|.|..:.|.: ::::||.:..:..|. |...||..:..|
Rat 878 AESELKELEQRH-----TQLAEEKTLLQ---EQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 934
Fly 949 QQRIDELNRDNS---------------NLKHKTSEISVLKMKLELKK-TLEAEFKNVK---AACQ 994
:.|::| ..|.| :|:.:..|....:.||:|:| |.||:.|.:: ....
Rat 935 EARLEE-EEDRSQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMD 998
Fly 995 DKDKLIEALNKQLE----------AERDEKMQLLEENGHAQEEWISQ-------KQTWRQENEEL 1042
|::..:....|.|| ||.:||.:.|.:.....|..||: ::..|||.|:|
Rat 999 DQNNKLSKERKLLEERVSDLTTNLAEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKL 1063
Fly 1043 RRQI--------DEIID-----------MAK------------NAEVNQRN-------------- 1062
:|:: ::|.| :|| :.|:.|:|
Rat 1064 KRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDEEITQKNNALKKIRELEGHVS 1128
Fly 1063 --QED-------RMLAEIDNRELNE----------------AYQRAIKDKEVIENENFMLKEELS 1102
||| |..||...|:|.| |.|:.::.|. |.|..|||:.|.
Rat 1129 DLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKR--EQEVTMLKKALD 1191
Fly 1103 RLTAGSFS-------LHARKASNASSQNEDDVGYASAKNTLDINRPPDLLSKNYSYNDSTSLVVK 1160
..|....: .|.:.....:.|.|. :..||..|| .||.....::..|..:
Rat 1192 EETRSHEAQVQEMRQKHTQAVEELTEQLEQ---FKRAKANLD-------KSKQTLEKENADLAGE 1246
Fly 1161 LRSILEEEKQ----KHKVLQEQYIKLSSR-----HKPTEDSFRVSELEVENEKLRSEYDQLR-TS 1215
|| :|.:.|| |.|.|:.|..:|.|: ...||.|.:|.:|:.|.|.:....::.. .:
Rat 1247 LR-VLGQAKQEVEHKKKKLEGQLQELQSKCSDGERARTELSDKVHKLQNEVESVTGMLNEAEGKA 1310
Fly 1216 IKHGVEINELNAQ----HAALQEEVRRRREECIQLKAVLLQQSQSMRSLEPE--SLQMRGNDVNE 1274
||...|:..|.:| ...||||.|:: |..|..:|.||.| ||| :.::|
Rat 1311 IKLAKEVASLGSQLQDTQELLQEETRQK-----------LNVSTKLRQLEDERNSLQ---DQLDE 1361
Fly 1275 LMEAFHSQKL------INRQLESELKAITEEHNSKLVEMTQEIERLNNEKDELQKVM-------- 1325
.||| .|.| :|.||....| ||.::...||.:...|..|||.|
Rat 1362 EMEA--KQNLERHVSTLNIQLSDSKK--------KLQDLASTIEVMEEGKKRLQKEMEGLGQQYE 1416
Fly 1326 -----FESID--------EFEDSNVDTLRQN-------------DRYLRRE-------------- 1350
::.:: |.:|..||...|. |:.|..|
Rat 1417 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRA 1481
Fly 1351 -------------LQKAVAQFLLVQEELKLANAKLKA-------YRQDGGQLEHKIE-------- 1387
|.:|:.:.|..:|||:..|..||| .:.|.|:..|::|
Rat 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1546
Fly 1388 --EEM------IRNKSNGT------------------SADVGANVTKQKSQNPQGLMKFHSSDL- 1425
||| :.::...| ..|:.|...:.:.:..|...:.|..:.
Rat 1547 QMEEMRTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE 1611
Fly 1426 --DKILQRLLSALTPRTVVGLLPGFPAYLIFMCIRYTDL-TNADDDVR------ELLSKFVIQIK 1481
|:..||.|:|...:.:.|.| .|| ..||..|: :.|.|...|:|
Rat 1612 LEDERKQRALAAAAKKKLEGDL--------------KDLELQADSAVKGREEAIKQLRKLQAQMK 1662
Fly 1482 KMHRTPHPIENRVIWLVNSITLLNLMKQYGDVDEYVKFNTEKQNQQQLKNFNLFEYRRVILDLIV 1546
...| .|.......||. |.|.|:|:::.|:.
Rat 1663 DFQR-------------------ELDDARASRDEI--FATSKENEKKAKSL-------------- 1692
Fly 1547 NLYQALIMQIQGLLDPKIVPAILNNDEIQRGRQAHGMRSR--ATSIGASSSPEHGGGPAWKQL-- 1607
:|.:||:|..| ...:|.|:...:... |..:.:|.|..:......::|
Rat 1693 ---EAELMQLQEDL-----------AAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEA 1743
Fly 1608 -IGQLEHFYKQFQHFGLDNCYAEQIFHQLLYFICAVALNCLMLRGDICMWETGMIIRYNIGCIED 1671
|.|||...:: |.| |:..:.|
Rat 1744 RIAQLEEELEE---------------------------------------EQG-----NMEAMSD 1764
Fly 1672 WVR-----SKKMSNDVLT----------ALAPLNQVSQLLQSRKSEQDVQTICDLCTSLST--AQ 1719
.|| ::::||:::| |...|.:.::.|:|:..|.:......|.::::. |:
Rat 1765 RVRKATLQAEQLSNELVTERSAAQKNESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAK 1829
Fly 1720 VLKVMKSYKLDDYESEITNVFLEKLTEKLNARQMQKSNSDEFTIDQKFIQPFKVVFRYSDIKLED 1784
::::.:..:.:..|.:.....|::..:||....:|..: ::|.::.:|......:.|::.
Rat 1830 IVQLEEQIEQEAREKQAATKLLKQKDKKLKEVLLQVED------ERKMVEQYKEQAEKGNTKVKQ 1888
Fly 1785 IE 1786
::
Rat 1889 LK 1890
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