|
Fly 1 MSSEEMLYAQGAKIWVPHADLVWESATLEESYRKGAGFLKICTDSGKLKEVKLKADGSDLPPLRN 65
|::.| ||.:.|::|:|..:.||:||.|.:.|:.|...|.:..:.||..|.:|.....:||.|||
Mouse 1 MAASE-LYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTGELPHLRN 64
Fly 66 PAILVGQNDLTTLSYLHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMPLYGPSIIRAYRG 130
|.||||:||||.|||||||.|||||||||.:.::|||||||:|||||||.::|:||..||.||.|
Mouse 65 PDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129
Fly 131 HAMGDLEPHIFALAEEAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVGGSESETQVER 195
..|||::|||||:|||||.::.|:..|.||||||||||||||||||||||||.|.||.||..||.
Mouse 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEE 194
Fly 196 KVLASSPIMEAFGNAKTTRNDNSSRFGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQGE 260
|||||:||||:.||||||||||||||||:.::.|..:..:: ||.|.||||||||||:||:.|
Mouse 195 KVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRII---GANMRTYLLEKSRVVFQAEEE 256
Fly 261 RNYHIFYQLCAARSKYPE---LVLDHQDKFQFLNMGGAPEIERVSDAEQFNETVQAMTVLGFSIQ 322
|||||||||||: :|.|| |.|.:.|.|.:...||:|.||.|.||::...|.||.|:||.|..
Mouse 257 RNYHIFYQLCAS-AKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISES 320
Fly 323 QIADIVKILAGILHLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQITADLLRVSADDLRRWLLM 387
....|.:||||||||||: |....|||||.|......|.|..||:.|..:::..||..
Mouse 321 YQMGIFRILAGILHLGNV--------GFASRDSDSCTIPPKHEPLTIFCDLMGVDYEEMCHWLCH 377
Fly 388 RKIESVNEYVLIPNSIEAAQAARDALAKHIYAKLFQYIVGVLNKSLNNGSKQCSFIGVLDIYGFE 452
||:.:..|..:.|.|...|..||||||||||||||.:||..:|::|::..||.||||||||||||
Mouse 378 RKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHSAVKQHSFIGVLDIYGFE 442
Fly 453 TFEVNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDFYDNQPCIDLIESRLGVLD 517
|||:||||||||||||||||||||.||||||||||:||.|.||:||||||||||:||||:||:||
Mouse 443 TFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILD 507
Fly 518 LLDEECRMPKGSDESWAGKLIG-KCNKFPHFEKPRFGTTSFFIKHFSDTVEYDVNGFLEKNRDTV 581
||||||:||||:|::||.||.. ..||...|||||....:|.||||:|.|||...||||||:|||
Mouse 508 LLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTV 572
Fly 582 SKELTQVLSESNMSLAKQVMTLEEIDTLCVDSAKSSTLGGRVVISAGRKQQGNDTRRRVVP---- 642
.:|..:||..|.. |.:..|.:.|...: |..|:|..||..: ||..|.|
Mouse 573 FEEQIKVLKSSKF---KMLPELFQDDEKAI-SPTSATSSGRTPL----------TRVPVKPTKGR 623
Fly 643 ----SKQHRKTVGSQFQESLASLISTLHATTPHYVRCIKPNDDKVAFKWETAKIIQQLRACGVLE 703
:|:|:||||.||:.||..|:.||:||||||||||||||.|..|.::..:.:||||||||||
Mouse 624 PGQTAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLE 688
Fly 704 TVRISAAGFPSRWLYPDFYMRYQLLVYRSKLDKNDMKLSCRNIVMKWIQDEDKYRFGNTQIFFRA 768
|:|||||||||||.|.:|:.||::|: :.|....|.|.:|:|::.|.|.|:|||:||.|:|||||
Mouse 689 TIRISAAGFPSRWTYQEFFSRYRVLM-KQKDVLGDRKQTCKNVLEKLILDKDKYQFGKTKIFFRA 752
Fly 769 GQVAFLEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARA 833
||||:||::||:..:.....:|..:|.::.|:::|.:|:....:|::.|||.||...:.:|..:|
Mouse 753 GQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKA 817
Fly 834 GLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAY 898
...:.||.|.::.||||...|.:...||:|.||.|.||::..:...|:||.||:.|||.|||..|
Mouse 818 ATTIQKYWRMYVVRRRYKIRRAATIVIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHY 882
Fly 899 QKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYMGLENKIISMQQRIDELNRDNSNLK 963
::..:.|:..|...||.:|:|:.|::|.||:::...:..::|:||||:.:|:::||.|:|...|.
Mouse 883 KRTMKAIVYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLM 947
Fly 964 HK--------TSEISVLKMKLELKKTLEAEFKNVKAACQDKDKLIEALNKQLEAERDEKMQLLEE 1020
.| .||...|:..:|..:..|.|.|..........:.|..|.|.||..|.||..:.|.
Mouse 948 EKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEER 1012
Fly 1021 NGHAQEEWISQKQTWRQENEELRRQID----EIIDMAKN-AEVNQRN--QEDRMLAEIDNRELNE 1078
....::|........::||..|:::.: .|::.||. .|..:|. :|.:.| |:|..:...
Mouse 1013 ADKYKQETDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQL-ELDLNDERL 1076
Fly 1079 AYQRAIKDKEVIENENFMLKEELSRLTAGSFSLHARKASNASSQNEDDVGYASA-KNTLDI-NRP 1141
.||..:.:...:|.....||||::.:.......|.|..|..|| ||.:..::|. ..|.|| .|.
Mouse 1077 RYQNLLNEFSRLEERYDDLKEEMTLMLNVPKPGHKRTDSTHSS-NESEYTFSSEFAETEDIAPRT 1140
Fly 1142 PDLLSKNYSYNDSTSLVVKLRSILEEEKQKHKVLQEQYIK-----LSSRHKPTE----------- 1190
.:.:.|....: .||.:||:..:.|.:|:.:::|::..: ..|:.|..|
Mouse 1141 EEPIEKKVPLD--MSLFLKLQKRVTELEQEKQLMQDELDRKEEQVFRSKAKEEERPQIRGAELEY 1203
Fly 1191 DSFRVSELEVENEKLRSEYDQLRTSI--KHGVEINE--------LNAQHAALQEEVRRRREECIQ 1245
:|.:..|||.||:||::|.::||.:: |...|:.. |..|..::.||:..|:||.:.
Mouse 1204 ESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLI 1268
Fly 1246 LKAVLLQQSQSMRSLEP--------------ESLQMRG-----------------------NDVN 1273
|::.|:.|.::::..:. :.::.:| |:..
Mouse 1269 LRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSTMDYQELNEDG 1333
Fly 1274 ELMEAFHSQKLINRQLESELKAITEEHNSKLVEMTQEIERLNNEKDELQKVMFESID-------- 1330
||...:...|..||.|||:|::....|.::...:..||:.|..|.:..|:::.:::.
Mouse 1334 ELWMVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIE 1398
Fly 1331 ---------------EFEDSNVDTLRQNDRY----------LRRELQKAVAQFLLVQEELKLANA 1370
.||:...|..::...| |..:|:|.......::::||:...
Mouse 1399 ASLQHEITRLTNENLYFEELYADDPKKYQSYRISLYKRMIDLMEQLEKQDKTVRKLKKQLKVFAK 1463
Fly 1371 KLKAYRQDGGQLEH----KIEEEMIRNKSNGTSADVGANVTKQKSQNPQGLMKFHSSDLDKILQR 1431
|:. ..:.||:|: :|.:|.|| ..|:.: |.::.||::::...|..|:::.
Mouse 1464 KIG--ELEVGQMENISPGQIIDEPIR----------PVNIPR-KEKDFQGMLEYKREDEQKLVKN 1515
Fly 1432 LLSALTPRTV-VGLLPGFPAYLIFMCIRYTDLTNADDDVRELLSKFVIQIKK-MHRTPHPIENRV 1494
|:..|.||.| |.|:||.|||::|||:|:.|..|.|..||.||:..:..||| :.:.....|...
Mouse 1516 LILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVS 1580
Fly 1495 IWLVNSITLLNLMKQYGDVDEYVKFNTEKQNQQQLKNFNLFEYRRVILDLIVNLYQALIMQIQGL 1559
.||.|:...|:.:|||...:.::|.||.:||:..|.||:|.|||:|:.||.:.:||.|:..::.:
Mouse 1581 FWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENI 1645
Fly 1560 LDPKIVPAILNNDEIQ--RGRQAHGMRSRATSIGASSSPEHGGGPAWKQLIGQLEHFYKQFQHFG 1622
|.|.||..:|.::.|| .|.:..|:|.|.:||... |......::.||..|:......|
Mouse 1646 LQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADE------GTYTLDSILRQLNSFHSVMCQHG 1704
Fly 1623 LDNCYAEQIFHQLLYFICAVALNCLMLRGDICMWETGMIIRYNIGCIEDWVRSKKMSND-VLTAL 1686
:|....:|:..|:.|.:.|:.||.|:||.|:|.|..||.||||:..:|:|:|.|.:.|. ....|
Mouse 1705 MDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETL 1769
Fly 1687 APLNQVSQLLQ-SRKSEQDVQTICDLCTSLSTAQVLKVMKSY-KLDDYESEITNVFLEKLTEKLN 1749
.||.|.:|||| .:|::.|.:.||.:|.:|:|||::||:..| .::::|..::..|:..:..:|.
Mouse 1770 EPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLR 1834
Fly 1750 ARQMQKSNSDEFTIDQKFIQPFKVVFRYSDIKLEDIELPSHLNLDEFLTKI 1800
.|: :|.:..:|.|.|.|....|..|.:.||.|::|:.|.|. |:.::
Mouse 1835 DRK----DSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLG-FIARV 1880
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