Protein Alignment dpa and MCM7

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_009761.4
• Gene: MCM7 / 852501
• SGDID: S000000406
• Length: 845
• Species: Saccharomyces cerevisiae
• Alignment Length: 767
• Identity: 251/767 - (32%)
• Similarity: 388/767 - (50%)
• Gaps: 139/767 - (18%)

  Fly   145 ESSQAPQLVVWGTNVVVSQCKSKFKSFIMRFID-----PSAEQDEISENIDV--------NQPLY 196
            :.:||..||     ..:.|..:.|.....|.||     |:.|.|...:.:||        |:.:.
Yeast    95 QGTQADDLV-----SAIQQNANHFTELFCRAIDNNMPLPTKEIDYKDDVLDVILNQRRLRNERML 154

  Fly   197 LQKLEEIH------TLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINEMFFERYPAA 255
            ..:..||.      |..:|..::|         |..|:::....|:.|              |..
Yeast   155 SDRTNEIRSENLMDTTMDPPSSMN---------DALREVVEDETELFP--------------PNL 196

  Fly   256 LLEHQIQVRPFN------------ADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFS 308
            ...:.:..:|.:            :.|..::|.:..:.:.|||::.|::.|.|:|.|.:....::
Yeast   197 TRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYT 261

  Fly   309 CNICSFSTTVEVDRGRINQPTLCTN--CNTNHC---FRLIHNRSEFTDKQLVKLQESPDDMAAGQ 368
            |:.|.:....||:.......:.||:  |:.|..   ..:....|:|:..|..|:||....:..|.
Yeast   262 CDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGH 326

  Fly   369 TPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATP------LKTGGLSSSVKSVYKTHVDV----VH 423
            .|.::.::.:..||..:.|||.|.||||:...|      ||.|.|:       :|:::.    .|
Yeast   327 IPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLT-------ETYLEAQFVRQH 384

  Fly   424 FRKVDNKRLYEDEEGKDHIFPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFG 488
            .:|..:..|..|.|        |||  ::|:. ..|:|:|||::|||.||.|.|:||.:||.|.|
Yeast   385 KKKFASFSLTSDVE--------ERV--MELIT-SGDVYNRLAKSIAPEIYGNLDVKKALLLLLVG 438

  Fly   489 GTKKKHATLG-RQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKD 552
            |..|:   :| ....|.:|::.|.||||.:|||:|:.:..:.||..||:|:|||.|||||.|.||
Yeast   439 GVDKR---VGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKD 500

  Fly   553 PETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILA 617
            |.|.:::|:.|||||||||:|||||||||::|.|:.:||||||||:||:||||...|||||||||
Yeast   501 PVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILA 565

  Fly   618 AANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEEED- 681
            ||||...::|.|.:.:||:.||..||||||::||:||......|::||.|:.   ||..|.::.
Yeast   566 AANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVT---YVHMHNKQPD 627

  Fly   682 ---TMFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMR---------KVGAGRGQISAYPR 734
               |..:.|.:|:|||||:.. .|.:|:.....::|||:.:|         |...|:    |.||
Yeast   628 LDFTPVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQ----ATPR 687

  Fly   735 QLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHR---EALKQSATDPLSGKIDVGILTTGLSTAA 796
            .|..:||||:|.||:||::.|::.|||||.||.|   |:|.|.               |..|...
Yeast   688 TLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQE---------------TNKSKED 737

  Fly   797 RKKRADLVAAIKENLKKKGKVLTVPYQKLFSDIKEGSQIMITREQFEDALKE 848
            ......:...||:.|::.|| .|:.|:.:...::.....|:   |..:.::|
Yeast   738 ESPTTKIFTIIKKMLQETGK-NTLSYENIVKTVRLRGFTML---QLSNCIQE 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039	1/4 (25%)
		MCM_N	165..267	CDD:464206	21/120 (18%)
		MCM	270..772	CDD:214631	211/533 (40%)
MCM7	NP_009761.4	MCM_N	59..138	CDD:464206	12/47 (26%)
		MCM	223..724	CDD:214631	210/529 (40%)