Protein Alignment dpa and MCM2

DIOPT Version :9

• Sequence 1: NP_001286160.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_009530.1
• Gene: MCM2 / 852258
• SGDID: S000000119
• Length: 868
• Species: Saccharomyces cerevisiae
• Alignment Length: 862
• Identity: 251/862 - (29%)
• Similarity: 392/862 - (45%)
• Gaps: 184/862 - (21%)

  Fly    46 SDNISLPPTSP-----GNISLPATSPARGLGA------------------------NMSEIDLSS 81
            |:| .|||:||     |.:: |.:||   :|:                        .|:|:||..
Yeast    16 SEN-ELPPSSPQQHFRGGMN-PVSSP---IGSPDMINPEGDDNEVDDVPDIDEVEEQMNEVDLMD 75

  Fly    82 PLNYG-----------TPSSMGSIRTPRSGIRGTPLRARPDIRTDKR---IRQVAI--------G 124
            ...|.           .|..:.........:..   |.|.|.:.::|   :|.||.        .
Yeast    76 DNMYEDYAADHNRDRYDPDQVDDREQQELSLSE---RRRIDAQLNERDRLLRNVAYIDDEDEEQE 137

  Fly   125 GGSGLE----PIPEK-----------------GSETTDPVSE--------SSQAPQLVVWGTNVV 160
            |.:.|:    |:..:                 .....||:.|        :.:|.....|.|...
Yeast   138 GAAQLDEMGLPVQRRRRRRQYEDLENSDDDLLSDMDIDPLREELTLESLSNVKANSYSEWITQPN 202

  Fly   161 VSQCKSK-FKSFIMRFIDPSAEQDEISENIDVNQPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQD 224
            ||:..:: .|||::.:.|            :..:.:|..::..:..:....|.:|..||......
Yeast   203 VSRTIARELKSFLLEYTD------------ETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAI 255

  Fly   225 LYRQLICYPQEVIPGFDMAINEMFFERYP-AALLEHQIQVRPFNADKTRNMRSLNPEDMDQLISI 288
            |...|...|:|::..||:...|.....|| .|.:..:|.||..:.....::|.|...::..|:.:
Yeast   256 LALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRV 320

  Fly   289 SGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQP-----------TLCTNCNTNHCFRL 342
            :|:|.|.:.|.|:::...|:|..|          |.|..|           :.||||.:...||:
Yeast   321 TGVVTRRTGVFPQLKYVKFNCLKC----------GSILGPFFQDSNEEIRISFCTNCKSKGPFRV 375

  Fly   343 IHNRSEFTDKQLVKLQESPDDMAAGQTPHN--VLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTG 405
            ...::.:.:.|.|.|||:|..:..|:.|.:  |:|.|  ||||..:||:.|.|||||:..  ..|
Yeast   376 NGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLA--DLVDVSKPGEEVEVTGIYKNN--YDG 436

  Fly   406 GLSSSVKS---VYKTHVDVVHFRKVDNKRLYEDEEGKDHIF--PPERVELLQLLAKKPDIYDRLA 465
            .|::  |:   |:.|.::....::.:.....|.|||.| :|  ..|.....:.:::...|.|::.
Yeast   437 NLNA--KNGFPVFATIIEANSIKRREGNTANEGEEGLD-VFSWTEEEEREFRKISRDRGIIDKII 498

  Fly   466 RAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVP 530
            .::|||||.:.|||..:...||||..|.  ..|:.:.|.:|::||.|||||:|||:|:||.....
Yeast   499 SSMAPSIYGHRDIKTAVACSLFGGVPKN--VNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAH 561

  Fly   531 RSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQ 595
            |:.:.:|:|:|||||||.|.|||.|::..|:.|||||||.|||.|||||||||..|:.:||.|||
Yeast   562 RAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQ 626

  Fly   596 QTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIF 660
            |::||:||||:..|.||.||:|||||...::|....:..||.|...:|||||::.:|.|..||..
Yeast   627 QSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEA 691

  Fly   661 DKRLASHLVSLYYVTRH--------------------------------------------EEED 681
            |:|||:.:|. .:|..|                                            |||.
Yeast   692 DERLATFVVD-SHVRSHPENDEDREGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEI 755

  Fly   682 TMFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQISAYPRQLESLIRLSEAH 746
            :.....:|..||.|||..:.|.|......::.:.|.|:|:.....|......|.|||::|::|:.
Yeast   756 SPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESF 820

  Fly   747 AKVRLSNQVELLDVEEA 763
            ||:|||..|...|::.|
Yeast   821 AKMRLSEFVSSYDLDRA 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_001286160.1	PHA03307	2..>150	CDD:223039	31/183 (17%)
		MCM_N	168..267	CDD:379644	22/99 (22%)
		MCM	270..772	CDD:214631	193/556 (35%)
MCM2	NP_009530.1	MCM2_N	49..193	CDD:403724	20/146 (14%)
		MCM_N	209..298	CDD:405270	22/100 (22%)
		MCM	302..846	CDD:214631	193/556 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54431
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820