DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpa and MCM6

DIOPT Version :9

Sequence 1:	NP_001286160.1	Gene:	dpa / 35679	FlyBaseID:	FBgn0015929	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_001331629.1	Gene:	MCM6 / 834492	AraportID:	AT5G44635	Length:	857	Species:	Arabidopsis thaliana

Alignment Length:	676	Identity:	237/676 - (35%)
Similarity:	351/676 - (51%)	Gaps:	72/676 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 FKSFIMRFIDPSAEQDE-------ISENIDVNQP-LYLQ-KLEEIHTLEEPYLNLNCAHLKTFDQ 223
            |..|:|   |..|.|.|       .|..:|.|:| ||.: ::|.|...|...:.::.:|:..|:.
plant     4 FGGFVM---DEQAIQVENVFLEFLKSFRLDANKPELYYEAEIEAIRGGESTMMYIDFSHVMGFND 65

  Fly   224 DLYRQLICYPQEVIPGFDMAINEMFFERYPAALLE----HQIQVRPFNADKTRNMRSLNPEDMDQ 284
            .|.:.:........|....|......|..|:.:.:    ..|.|..:|...|:.:|.|...::.:
plant    66 ALQKAIADEYLRFEPYLRNACKRFVIEMNPSFISDDTPNKDINVSFYNLPFTKRLRELTTAEIGK 130

  Fly   285 LISISGMVIRSSNVIPEMREAFFSCNIC-SFSTTVEVDRGRINQPTLCTN--CNTNHCFRLIHNR 346
            |:|::|:|.|:|.|.||:....|.|..| |....|| .:.:..|||:|.:  |.....:.|:...
plant   131 LVSVTGVVTRTSEVRPELLYGTFKCLDCGSVIKNVE-QQFKYTQPTICVSPTCLNRARWALLRQE 194

  Fly   347 SEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATP----LKTGGL 407
            |:|.|.|.|::||:..::.||..|.::.:...:::|::.:.||.|..||.....|    |...|.
plant   195 SKFADWQRVRMQETSKEIPAGSLPRSLDVILRHEIVEQARAGDTVIFTGTVVVIPDISALAAPGE 259

  Fly   408 -------SSSVKSVYKTHVDVVHF-------------------------RKVD-NKRLYEDEEGK 439
                   ||..||....|..|...                         |..| ..|..:..|..
plant   260 RAECRRDSSQQKSSTAGHEGVQGLKALGVRDLSYRLAFIANSVQIADGSRNTDMRNRQNDSNEDD 324

  Fly   440 DHIFPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGT-KKKHATLGRQNFR 503
            ...|..|.::.:|.:...||.:::|..::||:::.:.|||:.:||.|.||. |..|..:   |.|
plant   325 QQQFTAEELDEIQQMRNTPDYFNKLVGSMAPTVFGHQDIKRAVLLMLLGGVHKTTHEGI---NLR 386

  Fly   504 SEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLA 568
            .:|::.:.|||..:|||.|:|...:||||.||||:.|||.||||.|.|:|||.:..::.|||:||
plant   387 GDINVCIVGDPSCAKSQFLKYTAGIVPRSVYTSGKSSSAAGLTATVAKEPETGEFCIEAGALMLA 451

  Fly   569 DNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNII 633
            |||:|||||||||:...:..:||.|||||:||.||||...|||||||||||||...:::|.|.:.
plant   452 DNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGGRYDKSKPLK 516

  Fly   634 DNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEEE-DTMFDMSVLRDYIAYAR 697
            .||.||..:||||||:::::|..||:.|..:|.|:|.::  .:||.. ...|....|:.|||||:
plant   517 YNVNLPPAILSRFDLVYVMIDDPDEVTDYHIAHHIVRVH--QKHEAALSPEFTTVQLKRYIAYAK 579

  Fly   698 EHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQISAY---PRQLESLIRLSEAHAKVRLSNQVELLD 759
            . |.|.||.||::.|:::||.:|:.....|...||   .||||:|||||||.|:..|...|:...
plant   580 T-LKPKLSPEARKLLVESYVALRRGDTTPGTRVAYRMTVRQLEALIRLSEAIARSHLEILVKPSH 643

  Fly   760 VEEAWRLHREALKQSATDPLSGKIDV 785
            |..|.||    ||.|.....||.||:
plant   644 VLLAVRL----LKTSVISVESGDIDL 665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_001286160.1	PHA03307	2..>150	CDD:223039
		MCM_N	168..267	CDD:379644	25/111 (23%)
		MCM	270..772	CDD:214631	204/546 (37%)
MCM6	NP_001331629.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266497at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820