DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpa and PRL

DIOPT Version :9

Sequence 1:	NP_001286160.1	Gene:	dpa / 35679	FlyBaseID:	FBgn0015929	Length:	866	Species:	Drosophila melanogaster
Sequence 2:	NP_001190655.1	Gene:	PRL / 828153	AraportID:	AT4G02060	Length:	716	Species:	Arabidopsis thaliana

Alignment Length:	712	Identity:	239/712 - (33%)
Similarity:	356/712 - (50%)	Gaps:	97/712 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 KSKFKSFIMRFIDPSAEQDEISENIDVNQPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQDLYRQL 229
            |...|.|:..|.|.:..    |:.:::.|.:..:|:..|....:...|     .|...::...:|
plant    10 KGLAKGFLENFADANGR----SKYMEILQEVSNRKIRAIQVDLDDLFN-----YKDESEEFLGRL 65

  Fly   230 ICYPQEVIPGFDMAINEMF---FERYPAALLEHQIQVRPFNADKTRN------------------ 273
            ....:..:..|..|::|:.   .|.:|..  :|.|.:.....|.|.|
plant    66 TENTRRYVSIFSAAVDELLPEPTEAFPDD--DHDILMTQRADDGTDNPDVSDPHQQIPSEIKRYY 128

  Fly   274 --------------MRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGR 324
                          :|.:....:.||:.|||:|.|.|:|.|.|..|.::|..|......|| ..|
plant   129 EVYFKAPSKGRPSTIREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTCEDCGHEIYQEV-TSR 192

  Fly   325 INQPTLCTNCNTNHCFRLIH---------NRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHND 380
            :..|..  .|.::.| ||..         ..|:|...|..|:||..:.:..|..|.::.::...:
plant   193 VFMPLF--KCPSSRC-RLNSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHIPRSMTVHLRGE 254

  Fly   381 LVDKVQPGDRVTVTGIYRATPLKTG------GLSSSVKSVYKTHVDVVHFRKVDNKRLYEDEEGK 439
            |..||.|||.|..:||:...|. ||      ||   |...|.....|.||     |:.||:.|
plant   255 LTRKVSPGDVVEFSGIFLPIPY-TGFKALRAGL---VADTYLEATSVTHF-----KKKYEEYE-- 308

  Fly   440 DHIFPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATL-GRQNFR 503
               |..:..|.:..||:..|||::|:|::||.||.::||||.:||.|.|.   .|..| .....|
plant   309 ---FQKDEEEQIARLAEDGDIYNKLSRSLAPEIYGHEDIKKALLLLLVGA---PHRQLKDGMKIR 367

  Fly   504 SEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLA 568
            .::|:.|.||||.:|||:|:::.|:.||..||:|:|||.|||||.|.:|..|.::||:.||||||
plant   368 GDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAVMRDQVTNEMVLEGGALVLA 432

  Fly   569 DNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNII 633
            |.|:|.|||||||::|.|:.:||||||||:|||||||...|||||::|||||||..:::.|:...
plant   433 DMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRYDLRRTPA 497

  Fly   634 DNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEEEDTM----FDMSVLRDYIA 694
            :|:.||..|||||||::|:||..|...|..||.|::   :|.:.||...:    .:.::||.||:
plant   498 ENINLPPALLSRFDLLWLILDRADMDSDLELAKHVL---HVHQTEESPALGFEPLEPNILRAYIS 559

  Fly   695 YAREHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQISAYP--RQLESLIRLSEAHAKVRLSNQVEL 757
            .|| .|||.:..|.::.:..||..:|:..|......:|.  |.|.|::|:|.|.|::|.|..|..
plant   560 AAR-RLSPYVPAELEEYIATAYSSIRQEEAKSNTPHSYTTVRTLLSILRISAALARLRFSESVAQ 623

  Fly   758 LDVEEAWRL-HREALKQSATDPLSGKIDVGILTTGL--STAARKKRADLVAAIKEN-LKKKG 815
            .||:||.|| ....:...|.|.....:|....|..:  ..|||.|:..:..|...| :.:||
plant   624 SDVDEALRLMQMSKISLYADDRQKAGLDAISDTYSIIRDEAARSKKTHVSYANALNWISRKG 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_001286160.1	PHA03307	2..>150	CDD:223039
		MCM_N	168..267	CDD:379644	18/101 (18%)
		MCM	270..772	CDD:214631	207/556 (37%)
PRL	NP_001190655.1	MCM_N	16..98	CDD:405270	16/92 (17%)
PRL	NP_001190655.1	MCM	139..638	CDD:214631	205/523 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266497at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820