Protein Alignment dpa and MCM4

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_179236.3
• Gene: MCM4 / 816142
• AraportID: AT2G16440
• Length: 847
• Species: Arabidopsis thaliana
• Alignment Length: 873
• Identity: 372/873 - (42%)
• Similarity: 528/873 - (60%)
• Gaps: 99/873 - (11%)

  Fly    53 PTSPG-NISLPA----TSPA----RGLGANMSEIDLSSPLNYGTPSSMGSIRTPRSGIRGTPLRA 108
            |.||| |:|.|.    :|||    |..|.:      |:|..:.||....| |...|  ..||..:
plant    14 PPSPGENVSSPIENTYSSPAALHRRRRGRS------STPTQFATPPPPPS-RLASS--NSTPPTS 69

  Fly   109 RPDIRTDKRIRQVAIGGGSG-----------LEPIP------EKGSETTDPVSESSQAPQLVVWG 156
            ||.....|.......|||.|           .||:|      |.|.:.|.|.         .|||
plant    70 RPSAARSKGRNGHGGGGGGGGGGDPGTPMSTDEPLPSSDDGEEDGGDDTTPT---------FVWG 125

  Fly   157 TNVVVSQCKSKFKSFIMRFIDPSAEQDEISENIDVNQPLYLQKLEEIHTLEEPYLNLNCAHLKTF 221
            ||:.|...||..:.|:..|.:.....|::     ..:..|:..:.::..:|..:::::...:..:
plant   126 TNISVQDVKSAIEMFVKHFREARENSDDL-----FREGKYMVSIRKVIEIEGEWIDVDAFDVFDY 185

  Fly   222 DQDLYRQLICYPQEVIPGFDM-------AINEMFFERYPAALLEHQIQVRPFNADKTRNMRSLNP 279
            |.|||.:::.||.||:..||:       .||.:|         |..:|||.||...:.:||:|||
plant   186 DPDLYNKMVRYPLEVLAIFDIVLMDIVSTINRLF---------EKHVQVRIFNLRTSTSMRNLNP 241

  Fly   280 EDMDQLISISGMVIRSSNVIPEMREAFFSCNICS-FSTTVEVDRGRINQPTLC--TNCNTNHCFR 341
            .|::::||:.||:||||::|||:|||.|.|.:|. ||..:.||||:|::|..|  ..|.|.:...
plant   242 SDIEKMISLKGMIIRSSSIIPEIREAVFRCLVCGYFSDPIIVDRGKISEPPTCLKQECMTKNSMT 306

  Fly   342 LIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGG 406
            |:|||..|.|||:|:|||:||::..|.|||.|.|..|:.|||..:||||:.|||||||..::.|.
plant   307 LVHNRCRFADKQIVRLQETPDEIPEGGTPHTVSLLLHDKLVDNGKPGDRIEVTGIYRAMTVRVGP 371

  Fly   407 LSSSVKSVYKTHVDVVHFRK-------------VDN--KRLYEDEEGKDHIFPPERVELLQLLAK 456
            ...:||||:||::|.:|.:|             |||  :|:.||.|     ...|::...|.|:|
plant   372 AHRTVKSVFKTYIDCLHIKKASKLRMSAEDPMDVDNSLRRVDEDVE-----LDEEKLRKFQELSK 431

  Fly   457 KPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDPGTSKSQM 521
            :||||:||:|::||:|:|.||:|||:|.|||||.....|:  ..|||.:|::||.|||||||||:
plant   432 QPDIYERLSRSLAPNIWELDDVKKGLLCQLFGGNALNLAS--GANFRGDINILLVGDPGTSKSQL 494

  Fly   522 LQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTR 586
            |||:..|.||..||||||||||||||||.|||||.:.||::|||||:|.|:|||||||||:||.|
plant   495 LQYIHKLSPRGIYTSGRGSSAVGLTAYVAKDPETGETVLESGALVLSDRGICCIDEFDKMSDSAR 559

  Fly   587 SVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFL 651
            |:|||||||||:||||||||..||||||:||.|||:.|::|.|.::|:|:.||.|||||||||:|
plant   560 SMLHEVMEQQTVSIAKAGIIASLNARTSVLACANPSGSRYNPRLSVIENIHLPPTLLSRFDLIYL 624

  Fly   652 VLDPQDEIFDKRLASHLVSLYYVTRHEEEDTMFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAY 716
            :||..||..|:|||.|:|:|::......::...|::.|..|::|||:::.|.|||||.:.|.:.|
plant   625 ILDKPDEQTDRRLAKHIVALHFENAESAQEEAIDITTLTTYVSYARKNIHPKLSDEAAEELTRGY 689

  Fly   717 VDMRKVGAGRGQ----ISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALKQSATD 777
            |::||.|...|.    |:|.|||:|||||||||.|::|.|..||..||:||:||.|.|::|||||
plant   690 VELRKAGKFAGSSKKVITATPRQIESLIRLSEALARMRFSEWVEKHDVDEAFRLLRVAMQQSATD 754

  Fly   778 PLSGKIDVGILTTGLSTAARKKRADLVAAIKENLKKKGKV--LTVPYQKLFSDIKEGSQIMITRE 840
            ..:|.||:.::.||:|.:.|.:|....::|::...:|.::  .::...:|..::|:....:.|..
plant   755 HATGTIDMDLINTGVSASERMRRDTFASSIRDIALEKMQIGGSSMRLSELLEELKKHGGNINTEI 819

  Fly   841 QFEDALKEV---QDEGAIVVMGKNTIRI 865
            ...|..|.|   ..||.:|..|....|:
plant   820 HLHDVRKAVATLASEGFLVAEGDRIKRV 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039	35/122 (29%)
		MCM_N	165..267	CDD:464206	24/108 (22%)
		MCM	270..772	CDD:214631	279/523 (53%)
MCM4	NP_179236.3	PHA03307	<2..>76	CDD:223039	23/70 (33%)
		MCM_N	140..229	CDD:464206	22/102 (22%)
		MCM	232..747	CDD:475121	278/521 (53%)