Protein Alignment dpa and mcm9

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001333089.1
• Gene: mcm9 / 555610
• ZFINID: ZDB-GENE-041014-310
• Length: 1135
• Species: Danio rerio
• Alignment Length: 640
• Identity: 192/640 - (30%)
• Similarity: 309/640 - (48%)
• Gaps: 101/640 - (15%)

  Fly   168 FKSFIMRFIDPSAEQDEISENI-DVNQPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQDLYRQLIC 231
            |::::|.. ..|..|..:.||. |::.|:.:..:    ||.|..:.:.    :.|:        .
Zfish    17 FETYVMEH-HKSDIQQILQENTEDLHYPVVVNAM----TLFEDNMEVG----ECFN--------A 64

  Fly   232 YPQEVIPGFDMAINEMFFERYPAAL-------------LEHQIQVR----PFNADKTRNMRSLNP 279
            :|.:|:|.||.|:     :|...|:             |:|.:.||    |...:.||: .....
Zfish    65 FPSKVLPIFDNAL-----QRAAQAISQSSSSSPQDTFRLKHNMHVRISGLPVCPELTRD-HIPKA 123

  Fly   280 EDMDQLISISGMVIRSS--NVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCTNCNTNH-CFR 341
            .|:...:|::|.|||:|  .|:...|:  :.||.|....:|:....:....|..|:|.:.. |
Zfish   124 RDVGHFLSVTGTVIRTSVTKVLEYERD--YMCNKCRHVFSVQASFEQFYTFTPPTSCPSEEGC-- 184

  Fly   342 LIHNRSEFT-------------DKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTV 393
               ...:||             |.|.:|:||....::.|..|.::|:...:||||..:.||.:||
Zfish   185 ---GSFKFTCLSGSDAPPAACKDYQEIKIQEQVQKLSVGSIPRSMLIILEDDLVDSCKSGDDITV 246

  Fly   394 TGI--YRATPLKTGGLSSSVKSVYKTHVDVVHFRKVDNKRLYED-----EEGKD-HIFPP--ERV 448
            .|:  .|..|: .......|:.|.|.:...|:..:.....:.||     ||..| |...|  .|.
Zfish   247 YGVVCQRWKPM-FQDCRCDVEIVLKANYIEVNNEQSTTALVLEDIQKEFEEFWDSHKHDPIAGRN 310

  Fly   449 ELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGD 513
            |:|.              ::.|.::....:|..:.:.|.||.::..|:  ....|.|.||||.||
Zfish   311 EILM--------------SLCPQVFGMYVVKLAVAMVLAGGVQRIDAS--GTKVRGESHLLLVGD 359

  Fly   514 PGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEF 578
            |||.|||.|:|...:.|||..|:|.||:..|||....||  :.:..|:.|||||:|.|:||||||
Zfish   360 PGTGKSQFLKYAAKITPRSVLTAGIGSTNAGLTVAAVKD--SGEWHLEAGALVLSDGGLCCIDEF 422

  Fly   579 DKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLL 643
            :.:.:..|:.:||.|||||:|:||||::|:|:.||:||||.|| :.|::...::..||.|...||
Zfish   423 NSIKEHDRTSIHEAMEQQTISVAKAGMVCKLDTRTTILAATNP-KGQYDPNVSVSVNVALASPLL 486

  Fly   644 SRFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEEEDTMFDMSVLRDYIAYAREHLSPTLSDEA 708
            |||||:.::||.::..:||.::|.:  |.......|...::.|..:|.|....:. |.|.::.||
Zfish   487 SRFDLVLVLLDTKNPDWDKIISSFI--LQNKGAPSESLCLWSMEKMRAYFCLIKT-LKPRITPEA 548

  Fly   709 QQRLIQAYVDMRKVGAGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEA 763
             ..::..|..:::....|.......|.||||.||:||||::...   |.:.||:|
Zfish   549 -NTILSRYYQLQRQSDSRNAARTTIRMLESLSRLAEAHARLMFR---ETVTVEDA 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039
		MCM_N	165..267	CDD:464206	25/116 (22%)
		MCM	270..772	CDD:214631	167/520 (32%)
mcm9	NP_001333089.1	Mcm2	16..593	CDD:440854	188/632 (30%)
		MCM9	311..609	CDD:350666	115/315 (37%)