Protein Alignment dpa and mei-218

DIOPT Version :9

• Sequence 1: NP_001286160.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001027068.1
• Gene: mei-218 / 3772646
• FlyBaseID: FBgn0002709
• Length: 1186
• Species: Drosophila melanogaster
• Alignment Length: 889
• Identity: 167/889 - (18%)
• Similarity: 272/889 - (30%)
• Gaps: 318/889 - (35%)

  Fly     3 SPARSPSVGGATPKQGARTPTRGIASQDVETPMRMGPGRAVRPSDNISLPPTSPGNISLPATSPA 67
            |||:..||     ...:..|.| ||.:. :|....||. .|...|...:|||...:.......|.
  Fly   411 SPAKRASV-----TNNSSAPIR-IAPRQ-QTTQSSGPS-VVHNEDEDVMPPTPNQSERRQRRFPR 467

  Fly    68 RGLGANMSEIDLSSPLNYGTPSSM--GSIRTPRSGI-------RGTPLRARPDIRTDKRIRQVAI 123
            |.....|.. .|.:.....|.|.:  .|.:||...:       :...:::.|:|.....:|::|:
  Fly   468 RNHNPRMVR-SLQAVSREFTESLLEGSSGKTPEKEVVPYQQQEKPRQVKSSPEIHASSHMRKLAM 531

  Fly   124 G---GGSGLEPIPEKGSETTDPVSESSQAPQLVVWGTNVVVSQCKSKFKSFIMRFIDPSAEQDEI 185
            |   ..:..|..|...|..|..||..||             .:|:.:|..
  Fly   532 GSVLNSNAKEFHPTGESHLTHKVSRLSQ-------------RRCRQRFTR--------------- 568

  Fly   186 SENIDVNQPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINEMFFE 250
            |.:...|.|  .::|....:..||.|....   :..||.      |.|::.:   |..|..:
  Fly   569 SLHAKKNNP--REQLPNPDSAPEPILEYTS---EIDDQP------CPPRQTV---DTPIEAI--- 616

  Fly   251 RYPAALLEHQIQVRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFS 315
             .|.|::|         ...|.|:..:...|..     ||::  .||..|::
  Fly   617 -VPPAMIE---------VSATGNLPPVFYFDQQ-----SGII--WSNSSPQI------------- 651

  Fly   316 TTVEVDRGRINQPTL------CTNCNTNHCFRLIHNRSEFTDKQLVKLQESP---DDMAAGQTPH 371
             .||:....::|...      ||...|.       |...||        .||   ..|::.:.|
  Fly   652 -PVEIQSNSVSQSVFRLASLPCTGVGTT-------NMDIFT--------SSPPPIQHMSSSRLP- 699

  Fly   372 NVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGGLSSSVKSVYKTHV---------DVVHFRKV 427
                                  :.|...|.|.....|..|::.::.|:         |:::.|.:
  Fly   700 ----------------------SSISGPTQLSHTLSSPPVENQHQQHLWESCIHQDEDLMYSRPL 742

  Fly   428 -----------------------------DNKRLYEDEEGKDHIF------PP-ERVELLQLLAK 456
                                         ...::..||.|:::.:      || ||..:.:..::
  Fly   743 LDMDQEETQPEQQDQEWQWESEIEPPSFQSENQVVADEHGEENAYLAKDAGPPLERHMIFRAPSQ 807

  Fly   457 ------KPDI-----------------YDRLARAIAPSIYENDD--------IKKGILLQLFGGT 490
                  |||:                 |...:...|.|...:.|        ..|.|||...
  Fly   808 HGQEYPKPDLNCVPSSIKKLHHLISSQYSDYSFVYALSAQISQDCVPMDCFVYLKMILLASI--- 869

  Fly   491 KKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPET 555
                .::.....|:.|.|.:........:::|..|..|.||.     .|....||.......| |
  Fly   870 ----VSIESDEVRAPISLCIIATDSLMANRLLNKVGQLAPRF-----LGPHEYGLQPTFNALP-T 924

  Fly   556 RQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVME-------------------------- 594
            |...:....|:||..||....::::::......|.:.:|
  Fly   925 RFNWIVASPLLLAQQGVYYAGDWNRLSKDQGCQLEKCIENGAVPVPQLHIDQPLKAAVWTYWQPN 989

  Fly   595 ---QQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQ 656
               .|||::||   :|.:.. ..|...|..:.|.||   :||........::....|..    |:
  Fly   990 NSTNQTLALAK---LCPIFG-LPIYMGAQASNSLWN---SIIQKHNAEGQIVVNDGLSI----PE 1043

  Fly   657 DEIFDKRLASHLVSLYYVTRHEEEDTMFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRK 721
            |   |.|:..||:       |:.:                     .||:|.||..|.:.||..||
  Fly  1044 D---DMRMLIHLL-------HQRK---------------------TTLTDGAQHMLQKYYVISRK 1077

  Fly   722 VGAGRGQISAYPRQLES-----LIRLSEAHAKVRLSNQVELLDV 760
                     ..|....|     |.:|:|..||:.|..:|...||
  Fly  1078 ---------ERPNVFSSKTYIVLKQLAECFAKLALRLEVLESDV 1112

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_001286160.1	PHA03307	2..>150	CDD:223039	39/158 (25%)
		MCM_N	168..267	CDD:379644	17/98 (17%)
		MCM	270..772	CDD:214631	110/610 (18%)
mei-218	NP_001027068.1	PTZ00112	122..>417	CDD:240274	3/5 (60%)
		MCM	<1023..1116	CDD:278895	31/134 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11630
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100