Protein Alignment dpa and mcm4

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_944595.2
• Gene: mcm4 / 337598
• ZFINID: ZDB-GENE-030131-9544
• Length: 845
• Species: Danio rerio
• Alignment Length: 869
• Identity: 530/869 - (60%)
• Similarity: 666/869 - (76%)
• Gaps: 29/869 - (3%)

  Fly     1 MSSPARSPSVGGATPKQGARTPTRGIASQDVETPMRMGPGRAVRPSD---NISLPPTSPGNISLP 62
            ||||:      ..:.|:...||    ||:|..:|    |.:..|..|   .:...||||...:..
Zfish     1 MSSPS------SQSRKRDPPTP----ASEDPLSP----PSQRSRAHDTSTELQPMPTSPAQDASL 51

  Fly    63 ATSPARGLGANMSEIDLSSPLNYGTPSSMGSIRTPRSGIRGTPLRARPDIRTDKRIRQVAIGGGS 127
            .:||........||||.||||.||||||... .||||||||||.|.|.|:.:.::..||
Zfish    52 FSSPMAPRSVLQSEIDASSPLMYGTPSSRVE-GTPRSGIRGTPARQRADLGSVRKAPQV------ 109

  Fly   128 GLEPIPEKGSETTDPVSESSQAPQLVVWGTNVVVSQCKSKFKSFIMRFIDPSAEQDEISENIDVN 192
            .:...|..|....  ..:.....:||:|||:|.|..||.||:.|:.:|.||.:.::| :..:|:|
Zfish   110 DMHSEPASGDAAV--AGDQGAGQRLVIWGTDVNVGTCKEKFQRFLQQFTDPDSREEE-NAGLDLN 171

  Fly   193 QPLYLQKLEEIHTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINEMFFERYPAALL 257
            :|||:|||:||..:.||.||:||.|::|||.|||||||||||||||.|||::||:||:|:|.::|
Zfish   172 EPLYMQKLDEISVVGEPVLNVNCTHIQTFDADLYRQLICYPQEVIPTFDMSVNELFFDRFPDSVL 236

  Fly   258 EHQIQVRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDR 322
            ||||||||::|.||||||:|||||:||||:|||||||:|.:||||:||||.|.:|:|:|.|||||
Zfish   237 EHQIQVRPYSAIKTRNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFRCQVCAFNTRVEVDR 301

  Fly   323 GRINQPTLCTNCNTNHCFRLIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQP 387
            |||.:|.:|.||||.|...|:||||.|:|||::||||||:||.||||||..::||||||||||||
Zfish   302 GRIAEPAVCRNCNTTHSMALVHNRSVFSDKQMIKLQESPEDMPAGQTPHTTVVYAHNDLVDKVQP 366

  Fly   388 GDRVTVTGIYRATPLKTGGLSSSVKSVYKTHVDVVHFRKVDNKRLYE-DEEGKDHIFPPERVELL 451
            ||||.:||||||.|::.....|.||||||||:|.:||||.|.|||:. ||:|:..:|..|||.||
Zfish   367 GDRVNITGIYRAAPMRLNPRQSQVKSVYKTHIDAIHFRKTDEKRLHGLDEDGEQKLFTKERVALL 431

  Fly   452 QLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDPGT 516
            :.||.|||:|:||:.|:||||||::||||||||||||||:|.....||.|||:|:::||||||||
Zfish   432 KELAAKPDVYERLSSALAPSIYEHEDIKKGILLQLFGGTRKDFTQTGRGNFRAEVNILLCGDPGT 496

  Fly   517 SKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKM 581
            ||||:||||:|||||.|||||:|||||||||||.|||||||||||||||||:|||:|||||||||
Zfish   497 SKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKM 561

  Fly   582 NDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRF 646
            :|:|||||||||||||||||||||||||||||||||||||.|||||.:|..|:|:||||||||||
Zfish   562 SDNTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPVESQWNPKKTTIENIQLPHTLLSRF 626

  Fly   647 DLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEEEDTMFDMSVLRDYIAYAREHLSPTLSDEAQQR 711
            |||||:||||||.:|:|||.|||||||.:..:.|:...||:||:||||:||..:.|.||:||.|.
Zfish   627 DLIFLMLDPQDEAYDRRLAHHLVSLYYQSEEQIEEEHLDMAVLKDYIAFARTTVHPRLSEEASQA 691

  Fly   712 LIQAYVDMRKVGAGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALKQSAT 776
            ||:|||||||:|:|||.:|||||||||||||:|||||||.|.:||.:|||||.||||||||||||
Zfish   692 LIEAYVDMRKIGSGRGMVSAYPRQLESLIRLAEAHAKVRFSGKVETIDVEEAKRLHREALKQSAT 756

  Fly   777 DPLSGKIDVGILTTGLSTAARKKRADLVAAIKENLKKKGKVLTVPYQKLFSDIKEGSQIMITREQ 841
            ||.:|.:|:.|||||:|..|||::.::..|:|:.::.|||...:.||:||.|::..|:..||::.
Zfish   757 DPRTGFVDISILTTGMSATARKRKEEVAQALKKLIQSKGKTPAMKYQQLFDDLRGQSEAAITKDM 821

  Fly   842 FEDALKEVQDEGAIVVMGKNTIRI 865
            |::||:.:.||..:.|.|| |:|:
Zfish   822 FDEALRLLADEDYLTVTGK-TVRL 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039	50/150 (33%)
		MCM_N	165..267	CDD:464206	61/101 (60%)
		MCM	270..772	CDD:214631	367/502 (73%)
mcm4	NP_944595.2	PHA03307	1..>131	CDD:223039	51/152 (34%)
		MCM_N	145..246	CDD:464206	61/101 (60%)
		MCM	249..752	CDD:214631	367/502 (73%)