Protein Alignment dpa and Mcm3

DIOPT Version :9

• Sequence 1: NP_001286160.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001178734.2
• Gene: Mcm3 / 316273
• RGDID: 1305168
• Length: 813
• Species: Rattus norvegicus
• Alignment Length: 678
• Identity: 212/678 - (31%)
• Similarity: 342/678 - (50%)
• Gaps: 107/678 - (15%)

  Fly   158 NVVVSQCKSKFKSFIMRFIDPSAEQDEISENIDVNQPLYLQKLEEIHTLEEPYLN--LNCAHLKT 220
            :|.:.:.:..:..|:....|....|:::.|.|..||...:..:.::....|...|  ||.|
  Rat     9 DVELREAQRDYLDFLDDEEDQGIYQNKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNA---- 69

  Fly   221 FDQDLYRQLICYPQEVIPGFDMAINEMFFERYPAALLEHQIQVRPFNADKTRNMRSLNPEDMDQL 285
                 :.:|:.: |..:..|..:|:..:.::|.    |..|.:......|..:.|:|....:..:
  Rat    70 -----FEELVAF-QRALKDFVASIDATYAKQYE----EFYIGLEGSFGSKHVSPRTLTSCFLSCV 124

  Fly   286 ISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLC---------TNCNTNHCFR 341
            :.:.|:|.:.|.|.|::..:...|.    :|...::|...:..||.         |....|:...
  Rat   125 VCVEGIVTKCSLVRPKVVRSVHYCP----ATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLE 185

  Fly   342 LIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGG 406
            ..:..|.:.|.|.:.:||.|:...|||.|.:|.:...:||||||:||||:.|.|.||..|.|.||
  Rat   186 TEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKVKPGDRIQVVGTYRCLPGKKGG 250

  Fly   407 LSSSVKSVYKTHVDVVHFRKV----DNKRLYEDEEGKDHIFPPERVELLQLLAK--KPDIYDRLA 465
            .:|..            ||.|    :.|::.:|.:   ..|..:.:..::..:|  ..|::::||
  Rat   251 YTSGT------------FRTVLIACNVKQMSKDIQ---PAFSADDIAKIKKFSKTRSKDVFEQLA 300

  Fly   466 RAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVP 530
            |::||||:.:|.:||.||..|.||.:::  .....:.|.:|::||.|||..:|||:|:||....|
  Rat   301 RSLAPSIHGHDYVKKAILCLLLGGVERE--LENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAP 363

  Fly   531 RSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQ 595
            |:..|:|||||.|||||.||.|.||.:..|:.||:||||.||.||||||||:|..|:.:||||||
  Rat   364 RAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQ 428

  Fly   596 QTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIF 660
            ..::||||||..:||||.|:||||||...::::.|..::|:.|..:|||||||:|::||..|...
  Rat   429 GRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQ 493

  Fly   661 DKRLASHLVSLYY---------------------------VTRHEEEDT---------------- 682
            |:.::.|::.::.                           .|:.:::||
  Rat   494 DREISDHVLRMHQYRAPGEQDGDALPLGSSVDILATDDPDFTQDDQQDTRIYEKHDNLLHGSKKK 558

  Fly   683 ---MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKVG------AGRGQISAYPRQLES 738
               |...:.::.||..|: .:.|||:.|:...:.:.|..:|...      |....::|  |.||:
  Rat   559 REKMVSAAFMKKYIHVAK-IIKPTLTQESAAYIAEEYSRLRSQDSMSSDTARTSPVTA--RTLET 620

  Fly   739 LIRLSEAHAKVRLSNQVELLDVEEAWRL 766
            ||||:.||||.|:|..|:|.|.|||..|
  Rat   621 LIRLATAHAKARMSKTVDLQDAEEAVEL 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_001286160.1	PHA03307	2..>150	CDD:223039
		MCM_N	168..267	CDD:379644	19/100 (19%)
		MCM	270..772	CDD:214631	192/564 (34%)
Mcm3	NP_001178734.2	MCM_N	17..129	CDD:291233	22/125 (18%)
		MCM	109..654	CDD:214631	192/564 (34%)
		P-loop_NTPase	340..479	CDD:304359	77/138 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820