Protein Alignment dpa and Mcm6

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_511065.1
• Gene: Mcm6 / 31603
• FlyBaseID: FBgn0025815
• Length: 817
• Species: Drosophila melanogaster
• Alignment Length: 757
• Identity: 235/757 - (31%)
• Similarity: 370/757 - (48%)
• Gaps: 96/757 - (12%)

  Fly   173 MRFIDPSAEQDEISENIDVN-QPLYLQKLEEIH------------TLEEP---YLNLNCAHLKTF 221
            |...|....|..:.:.:.:. |.|:...|||..            :||.|   .|.::...::.:
  Fly     1 MDVADAQVGQLRVKDEVGIRAQKLFQDFLEEFKEDGEIKYTRPAASLESPDRCTLEVSFEDVEKY 65

  Fly   222 DQDLYRQLICYPQEVIPGFDMAINEMFFERYP------AALLEHQIQVR-------PFNADKTRN 273
            ||:|               ..||.|.::..||      :..::.:|.::       .|....||:
  Fly    66 DQNL---------------ATAIIEEYYHIYPFLCQSVSNYVKDRIGLKTQKDCYVAFTEVPTRH 115

  Fly   274 -MRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCTN--CN 335
             :|.|....:..||.|||.|:|:..|.||:....|.|..|.........:.:...||:|.|  |:
  Fly   116 KVRDLTTSKIGTLIRISGQVVRTHPVHPELVSGVFMCLDCQTEIRNVEQQFKFTNPTICRNPVCS 180

  Fly   336 TNHCFRLIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRAT 400
            ....|.|...:|.|.|.|.:::||:..::..|..|..|.:...::||:.||.|||...||.....
  Fly   181 NRKRFMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVV 245

  Fly   401 P----LKTGGLSSSVKSVYK--------THVDVVHFRKVDNKRLY-------------------- 433
            |    |...|..:...|.:|        |.:..:..|:::.:..:
  Fly   246 PDVSVLAGVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFLACSVQATTARFGGTDLPMS 310

  Fly   434 --EDEEGKDHIFPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHAT 496
              ..|:.|..:...|..::.: ::|..::|..|..::.||||.||::|:|||||.|||..|  .|
  Fly   311 EVTAEDMKKQMTDAEWHKIYE-MSKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAK--TT 372

  Fly   497 LGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQ 561
            ..:.:.|.:|::.:.|||.|:|||.|:.|.:..||:.||||:.|||.||||.|.:|.|:...|::
  Fly   373 TEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIE 437

  Fly   562 TGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQW 626
            .|||:|||||:|||||||||:...:..:||.|||||:|||:||:...|||||||||||||...::
  Fly   438 AGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAGVRATLNARTSILAAANPINGRY 502

  Fly   627 NKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEEEDTMFDMSVLRD 691
            ::.|::..|:||...::|||||.|:::|..:|:.|..:|..:|.|:.......|.......|||
  Fly   503 DRSKSLQQNIQLSAPIMSRFDLFFILVDECNEVVDYAIARKIVDLHSNIEESVERAYTREEVLR- 566

  Fly   692 YIAYAREHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQISAY---PRQLESLIRLSEAHAKVRLSN 753
            |:.:||: ..|.:|.||...|::.|..:|:...|....|.:   .|||||:||||||.||:..||
  Fly   567 YVTFARQ-FKPVISQEAGHMLVENYGHLRQRDTGTSGRSTWRITVRQLESMIRLSEAMAKLECSN 630

  Fly   754 QVELLDVEEAWRLHREALKQSATDPLSGKIDVGI-LTTGLSTAARKKRADLVAAIKEN----LKK 813
            :|....|:||:||..:::.:.....:....|.|: :..|:......:.....|.:.||    ...
  Fly   631 RVLERHVKEAFRLLNKSIIRVEQPDIHLDDDEGLDMDDGIQHDIDMENNGAAANVDENNGMDTSA 695

  Fly   814 KGKVLTVPYQKLFSDIKEGSQIMITREQFEDALKEVQ--DEG 853
            .|.|....:...|.|.|..|.:::...:.|:|..||:  |.|
  Fly   696 SGAVQKKKFTLSFEDYKNLSTMLVLHMRAEEARCEVEGNDTG 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039
		MCM_N	165..267	CDD:464206	21/122 (17%)
		MCM	270..772	CDD:214631	195/541 (36%)
Mcm6	NP_511065.1	MCM_N	22..109	CDD:464206	18/101 (18%)
		MCM	113..649	CDD:475121	195/540 (36%)
		MCM6_C	702..816	CDD:465688	10/36 (28%)