Protein Alignment dpa and mcm7

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_997734.1
• Gene: mcm7 / 192333
• ZFINID: ZDB-GENE-020419-27
• Length: 721
• Species: Danio rerio
• Alignment Length: 739
• Identity: 251/739 - (33%)
• Similarity: 377/739 - (51%)
• Gaps: 95/739 - (12%)

  Fly   165 KSKFKSFIMRF-------------------------------IDPSAEQD-EISENIDVNQPLYL 197
            |.|.|.|:..|                               :|..||:| ::.|::..|...|.
Zfish    10 KEKCKRFLQEFYTEDDSGKKIFKYGAQLVSLAHREQVALLVDLDDVAEEDPDLVESVCENAKRYT 74

  Fly   198 QKL-EEIHTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINEMFFERYPAALLEH-Q 260
            ... :.||.|...|...........|..:..:|:.    .:.|.|.|......::||..|:.. :
Zfish    75 ALFADAIHELLPEYREREAVVKDALDVYIEHRLMM----EVRGRDPADTRDHRKQYPPELMRRFE 135

  Fly   261 IQVRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRI 325
            :..||....|.|.:|.:..:.:.||:::.|:|.|::.|.|.|..|.::|:.|...|...:.....
Zfish   136 VYFRPPATLKPRVVRDVKADSIGQLVTVRGIVTRATEVKPMMAVATYTCDQCGAETYQPIASPSF 200

  Fly   326 NQPTLCTN--CNTNHC---FRLIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKV 385
            ....:|.:  |.||..   ..|....|:|...|.:::||..|.:..|..|.::.:||..:.....
Zfish   201 TPLIMCPSQECVTNKSGGRLYLQTRGSKFIKFQELRIQEHSDQVPVGNIPRSMTIYARGENTRVA 265

  Fly   386 QPGDRVTVTGIYRATPLKTGGLSSSVKSVY-KTHVDVVHFRKVDNKRLYEDEEGKDHIFPPERVE 449
            ||||.|.|:|::  .||...|...:|:.:. :|::: .|...:.|| ..:||.|.:.:...|..:
Zfish   266 QPGDHVAVSGVF--LPLLRSGFRQAVQGLLSETYLE-CHSITLMNK-TEDDELGTEELSDEELRQ 326

  Fly   450 LLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDP 514
            :.:     .|.|::||.:|||.||.::|:||.:||.|.||.::  |..| ...|..|::.|.|||
Zfish   327 ITE-----EDFYEKLAGSIAPEIYGHEDVKKALLLLLVGGVEQ--APRG-MKIRGNINICLMGDP 383

  Fly   515 GTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFD 579
            |.:|||:|.|:..|.||||||:|||||.|||||.|.:||.|.::.|:.|||||||.|||||||||
Zfish   384 GVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVMRDPVTGEMTLEGGALVLADLGVCCIDEFD 448

  Fly   580 KMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLS 644
            ||.|:.|:.:||||||||:|||||||:..||||.|||||||||..::|.||:|..|:|||..|||
Zfish   449 KMADADRTAIHEVMEQQTISIAKAGIMTSLNARCSILAAANPAYGRYNPRKSIEQNIQLPAALLS 513

  Fly   645 RFDLIFLVLDPQDEIFDKRLASHLVSLYYVTRHEEED----TMFDMSVLRDYIAYAREHLSPTLS 705
            ||||::|:.|..|...|.|||.|:.   ||.:|..:.    |..||.::|.||:..::. .|.:.
Zfish   514 RFDLLWLIQDRPDAESDLRLAQHIT---YVHQHCRQPPTHFTPIDMKLMRRYISKCKQK-QPVVP 574

  Fly   706 DEAQQRLIQAYVDMRK-VGAGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHRE 769
            :.....:..|||:||| ....:.......|.|.|::|||.|.|::|:.:.||..||.||.|| .|
Zfish   575 ESLSDYITAAYVEMRKEARVSKDTTFTSARTLLSILRLSTALARLRMVSVVEKEDVNEAMRL-ME 638

  Fly   770 ALKQSATDPLSGKIDVGILTTGLSTAARKKR-ADLVAAIKENL--KKKGKVLTVPYQKLFSDIKE 831
            ..|.|             |....|:::|.:| ||::.::...|  :..|:.:.|         ..
Zfish   639 MSKDS-------------LQADRSSSSRAQRPADVIFSLLRELCGESAGRSVRV---------SA 681

  Fly   832 GSQIMITR----EQFEDALKEVQD 851
            ..|..::|    .||:.||:|.::
Zfish   682 AEQRCVSRGFTPAQFQAALQEYEE 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039
		MCM_N	165..267	CDD:464206	26/135 (19%)
		MCM	270..772	CDD:214631	207/512 (40%)
mcm7	NP_997734.1	MCM_N	10..103	CDD:464206	17/92 (18%)
		MCM	145..641	CDD:475121	207/512 (40%)