Protein Alignment dpa and mcm-7

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_504199.1
• Gene: mcm-7 / 178831
• WormBaseID: WBGene00003159
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 726
• Identity: 236/726 - (32%)
• Similarity: 373/726 - (51%)
• Gaps: 81/726 - (11%)

  Fly   169 KSFIMRFIDPSAEQD-----EISENIDVNQPLY--LQKLEEIHTLEEPYL-NLNCAHLKTFDQDL 225
            |..|:..:|...|.|     |:||.|..|...|  |.| :.|..:.:.|| :.....:...|..:
 Worm    50 KQAIVVNVDHIKESDIPDALELSEAITSNTKRYEVLFK-DTISDMIQDYLGDKQAPVIDALDAYM 113

  Fly   226 YRQLICYPQEVIPGFDMAINEMFFERYPAALLEH-QIQVRPFNADKTRNMRSLNPEDMDQLISIS 289
            :::|.....|.....::::.:. .::||..||:. ::.....:|.....:|::...::..|:|:.
 Worm   114 FQRLHMDRNEGAANEEVSLQDK-RKKYPPQLLQRFEVYFTTDDAAHETCVRNIKATEIGHLVSMK 177

  Fly   290 GMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCTNCNTNHCFRL-----IHNR--- 346
            |:|||::.|.|.:....::|:.|:......|...:...|   .||....|...     :|.:
 Worm   178 GVVIRATEVKPCVEVMTYTCDTCAAEVYQPVKGMQFTPP---VNCPNKECVEAKANGRLHMQLRG 239

  Fly   347 SEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATPLKTGGLSSSV 411
            |:|...|.:|:||..:.:..|..|..:.::.:.::..|...|:.|.|:|::  .|:...|...:.
 Worm   240 SKFVKFQELKIQELSEQVPVGSIPRTMTVHVYGEMTRKCNTGNVVHVSGVF--LPIMQSGFRPTG 302

  Fly   412 KSVYKTHVDVVHFRKVDNKRLYEDEEGKDHIFPPERVELLQLLAKKPDIYDRLARAIAPSIYEND 476
            ..|..|:::..:...:|:...:...:..:          |::|.:|.|.|:.||.:|||.|:.:.
 Worm   303 GLVADTYLEAHYINNLDDNPTFNGVQSAE----------LEVLRRKGDNYETLAASIAPEIFGHV 357

  Fly   477 DIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSS 541
            |:||.:|:.|.||...   :......|..|::|:.||||.:|||:|.||..|.||||||:|||||
 Worm   358 DVKKCLLMALVGGNDN---SSNGMKIRGCINVLMMGDPGVAKSQLLGYVNRLAPRSQYTTGRGSS 419

  Fly   542 AVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGII 606
            .|||||.|.|||.|.::.|:.|||||||.|:|||||||||.|..|:.:||||||||:|||||||:
 Worm   420 GVGLTAAVMKDPVTGEMSLEGGALVLADGGICCIDEFDKMMDHDRTAIHEVMEQQTISIAKAGIM 484

  Fly   607 CQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSL 671
            ..|||||:|:||||||..::|..::|..||.||..||||||||.|:.|..|...||.||.|:.
 Worm   485 TTLNARTAIIAAANPAYGRYNPNRSIEQNVDLPAALLSRFDLILLMQDKADRENDKILAEHIT-- 547

  Fly   672 YYVTRH-----EEEDTMFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRK-VGAGRGQIS 730
             ||.:|     .|:..:..:..||:||:..:.: :||:....::|:::|||:||: .........
 Worm   548 -YVHQHGCHPNREKKDLISLETLREYISLCKTY-TPTVDPALRERIVEAYVEMRRDARYSSDPTF 610

  Fly   731 AYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGILTTGLSTA 795
            ..||.:..::|::.|.||:|||..|:..|||||.||.:.|  :.:..|...||:
 Worm   611 VSPRMILGIVRMATARAKLRLSTIVDESDVEEALRLMQFA--KDSLRPEQNKIE----------- 662

  Fly   796 ARKKRADLVAAIKENLKKKGKVLTVPYQKLFSD-----IKEGSQIMITREQFEDALKEVQDE--- 852
              |:.|.:.||.        .||...|.   :|     |....|....:...|.|||:..|:
 Worm   663 --KRMAPVDAAF--------AVLRELYH---ADNAPIAISNAIQRCARKGISEVALKKCLDQYTA 714

  Fly   853 GAIVVMGKNTI 863
            ..::||.:..|
 Worm   715 NGLLVMDRQNI 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039
		MCM_N	165..267	CDD:464206	23/106 (22%)
		MCM	270..772	CDD:214631	191/515 (37%)
mcm-7	NP_504199.1	MCM_N	14..107	CDD:464206	16/57 (28%)
		MCM	162..651	CDD:475121	191/512 (37%)