Protein Alignment dpa and mcm-6

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001023011.1
• Gene: mcm-6 / 176385
• WormBaseID: WBGene00003158
• Length: 810
• Species: Caenorhabditis elegans
• Alignment Length: 775
• Identity: 238/775 - (30%)
• Similarity: 375/775 - (48%)
• Gaps: 101/775 - (13%)

  Fly   156 GTNVVVSQCKSKFKSFIMRFIDPSAEQDEISENIDVNQPLYLQKLEEIHTLEEPYLNLNCAHLKT 220
            ||.|     :::|..|:..|.|..            |:.:|...::|:...|:..:.:|..||..
 Worm    17 GTRV-----QNEFSKFLKSFKDQK------------NEFIYKSAMKELVQPEKNTIFINMQHLYK 64

  Fly   221 FDQDLYRQLICYPQEVIP----GFDMAINEMFFERYPAALLEHQIQVRPFNADKTRNMRSLNPED 281
            |..:|...:......|.|    ...:|..:...|.....:.:.|:.|..||.|....:|.|:.:.
 Worm    65 FSNNLATTIELQYYRVYPFMCEALHLATLDACDESERQQMFKKQLYVSLFNLDAKTKVRELSADK 129

  Fly   282 MDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCTN--CNTNHCFRLIH 344
            :..|:.|:|.::|:..|.||:..|.|.|..|..:|.....:.|..|||.|.|  |.....|.|..
 Worm   130 VGGLVRIAGQIVRTHPVHPELSRACFVCEDCGVTTRDVQQQFRYTQPTKCANPQCMNRTRFSLDV 194

  Fly   345 NRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYRATP----LKTG 405
            |.|.|.|.|.:::||:..::..|..|..|.:....::|:.|||||:..:.|.....|    |.|.
 Worm   195 NSSTFVDFQKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQPGDKCDIVGTLIVIPDIAQLSTP 259

  Fly   406 GLSSSV----------KSVYKTHVDVVHFRKVDNKRLY--------EDEEGKDHIFPPERVELLQ 452
            ||.:..          ||...|.:..:..|.:..|..:        |...|.|.....|..:.|.
 Worm   260 GLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAFLACHIQQTESLVGGDASGAVEETDYLD 324

  Fly   453 L-----------LAKKPD---IYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFR 503
            |           |.|..|   |...:..::.|:||.|.::|.|:||.|.||..||....| .:.|
 Worm   325 LWSKMSTEDRATLKKMSDDKKIEKNIVDSLFPNIYGNHEVKLGVLLMLLGGVAKKSRDEG-TSLR 388

  Fly   504 SEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLA 568
            .:|::.|.|||.|:|||:|:.|....||:.||||:.|||.||||.|.||.|:.:.|::.|||:||
 Worm   389 GDINVCLVGDPSTAKSQVLKAVEEFSPRAIYTSGKASSAAGLTAAVVKDEESFEFVIEAGALMLA 453

  Fly   569 DNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNII 633
            |||||||||||||:...:..:||.|||||:||.|||:...||||.||||||||...::::.:.:.
 Worm   454 DNGVCCIDEFDKMDLKDQVAIHEAMEQQTISITKAGVKATLNARASILAAANPVNGRYDRSRPLK 518

  Fly   634 DNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLY-YVTRHEEEDTMFDMSVLRDYIAYAR 697
            .|||:...::|||||.|:::|..:|:.|..:|..::..: .::.|.|.|:::.:..::.|||:||
 Worm   519 YNVQMSAPIMSRFDLFFVLVDECNEVTDYAIARRILDNHRAISEHTERDSVYKIDDIKKYIAFAR 583

  Fly   698 EHLSPTLSDEAQQRLIQAYVDMRKVGAGRGQISAY---PRQLESLIRLSEAHAKVRLSNQVELLD 759
             ...|.:||:|.:.|::.|..:|...:.....|::   .||||||:|||||.|::....:|.:..
 Worm   584 -CFKPKISDKAAETLVREYKKLRMSDSNNAATSSWRITVRQLESLVRLSEALARLHCGKEVLVEH 647

  Fly   760 VEEAWRLHREALKQSATDPLS---GKIDVGILTTGLSTAARKKRADLVAAIKENLK--------- 812
            ||:|..|..:::.:.....::   ...|..|:              :|.|.|||.:
 Worm   648 VEKAAELLNKSIVRVEQPDIALDDDDFDNNIM--------------VVEADKENQRGDDSMDHDG 698

  Fly   813 KKGKVLTVPYQKL---FSDIKEGSQIMITR------EQFEDALKEVQDEGAIVVMGKNTI 863
            :|.....:...||   |.:.|:.|.:::..      .|.||....|: :.|:|....:||
 Worm   699 EKENAPKIDIAKLKISFKEYKQLSDVLVLHMRSDEDNQGEDEYDGVK-QSALVEWYLSTI 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039
		MCM_N	165..267	CDD:464206	19/105 (18%)
		MCM	270..772	CDD:214631	192/543 (35%)
mcm-6	NP_001023011.1	MCM_N	21..115	CDD:464206	19/105 (18%)
		MCM	119..660	CDD:214631	192/542 (35%)
		MCM6_C	710..807	CDD:465688	13/49 (27%)