Protein Alignment dpa and mcm-5

DIOPT Version :9

• Sequence 1: NP_001286160.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_497858.1
• Gene: mcm-5 / 175552
• WormBaseID: WBGene00003157
• Length: 759
• Species: Caenorhabditis elegans
• Alignment Length: 778
• Identity: 245/778 - (31%)
• Similarity: 395/778 - (50%)
• Gaps: 118/778 - (15%)

  Fly   132 IPEKGSETTDPVSESSQAPQLVVWGTNVVVSQCKSKFKSFIMRFIDPSAEQDEISENIDVNQPLY 196
            :|:.|.|..      ::..||:            ::|::||..|.......            :|
 Worm    21 VPDTGRELI------AEYRQLI------------TQFRNFIRDFSTGGFGM------------IY 55

  Fly   197 LQKLEEIHTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMA----INEMFFERYPAALL 257
            ..:|:..:...|..|.:|..|||.||:|:..:|..:|.:|:|..:.|    .:|:...|......
 Worm    56 RDQLKRNYFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPALEEAAKIVADEITTPRPKGEEK 120

  Fly   258 EHQIQVRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFS-TTVEVD 321
            .|.|||.....:...::|.:....:.|::.|||:::.::.|..:..:....|..|..: ..|.:.
 Worm   121 LHDIQVTLTLDEYPTSLRQVKSAQVSQVVKISGIIVAAAQVRSKATKVTLQCRQCKHTIPDVSIK 185

  Fly   322 RG--RINQPTLCT---NCNTNHC----FRLIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYA 377
            .|  ....|..|.   ......|    :.::.::.|..|.|.:||||:|:|:..|:.|.::.|:.
 Worm   186 PGLEGFALPRTCAAPQQGQMQRCPIDPYIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHLQLFT 250

  Fly   378 HNDLVDKVQPGDRVTVTGIYRATPL--KTGGLSSSVKSVYKTHVDV--VHFRKVDNKRLYEDEEG 438
            ...|.|||.||:|||:.|:|....|  |.|| ..|::.:...::.|  :|        :.....|
 Worm   251 ERYLTDKVVPGNRVTIVGVYSIKKLIQKKGG-DKSLQGIRTPYLRVLGIH--------METSGPG 306

  Fly   439 KDHI--FPPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHAT-LGRQ 500
            :.:.  |.||...:.:.||::.|.|:.:|::||||||.:.||||.|...||||.:||... :.|
 Worm   307 RTNFTTFTPEEERMFKTLAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITR- 370

  Fly   501 NFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGAL 565
              |.:|::||.|||||:|||:|::|..:.|...||||:||||.||||.|.:||::|..:::.||:
 Worm   371 --RGDINVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRDPQSRSFIMEGGAM 433

  Fly   566 VLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRK 630
            ||||.||.||||||||.:..|..:||.|||||:|||||||...||:|.|:|||||....:|::.:
 Worm   434 VLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGRWDESR 498

  Fly   631 NIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYY-VTRHEEED------------- 681
            . .||:....|:|||||:|::|.|..|.:.|..||.|::.::. .:..:|.|
 Worm   499 G-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKERDIAGVPKTATTDSD 562

  Fly   682 ---TMFD------MSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMR---------KVGAGRGQ 728
               ||||      :..|:.::.|||.:..|.|:.:|.::|:..||.||         |.|. :..
 Worm   563 GVMTMFDTDGFLTIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRNPVVNADAFKSGK-KAH 626

  Fly   729 ISAYP---RQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHR-EALKQSATDPLSGKIDVGILT 789
            .||.|   ||||:::|::|:.||:.|........||||.||.| ..::.:||..|:|       .
 Worm   627 NSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRLFRVSTIEAAATGNLAG-------V 684

  Fly   790 TGLSTAARKKRADLVAAIKENLKKKGKVLTVPYQKLFSDIKEGSQIMITREQFEDAL-KEVQD 851
            .|.::.|.:   :.:..|:..:||:..:.|...:.|.      .|..:.|:.:.::| |:|.|
 Worm   685 EGFTSTADQ---EALNRIEVQMKKRFAIGTHVSEHLI------VQDFVARQHYRESLVKKVID 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_001286160.1	PHA03307	2..>150	CDD:223039	3/17 (18%)
		MCM_N	168..267	CDD:379644	26/102 (25%)
		MCM	270..772	CDD:214631	197/554 (36%)
mcm-5	NP_497858.1	MCM_N	38..153	CDD:291233	29/126 (23%)
		MCM	134..673	CDD:214631	197/552 (36%)
		AAA	375..516	CDD:99707	78/141 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820