Protein Alignment dpa and Mcm5

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_032592.2
• Gene: Mcm5 / 17218
• MGIID: 103197
• Length: 734
• Species: Mus musculus
• Alignment Length: 752
• Identity: 243/752 - (32%)
• Similarity: 388/752 - (51%)
• Gaps: 101/752 - (13%)

  Fly   141 DPVSESSQAPQLVVWGTNVVVSQCKSKFKSFIMRFIDPSAEQDEISENIDVNQP----LYLQKLE 201
            ||.:|..||.:          ||.:.:||.|:.::            .:..::.    .|..:|:
Mouse    18 DPGAEEGQARK----------SQLQRRFKEFLRQY------------RVGTDRTGFTFKYRDELK 60

  Fly   202 EIHTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINEMFFE----RYPAALLEHQIQ 262
            ..:.|.|.::.:....|.:||::|...|...|.|.:...:.|..|:..|    |.....|...||
Mouse    61 RHYNLGEYWIEVEMEDLASFDEELADHLHKQPAEHLQLLEEAAKEVADEVTRPRPAGDELLQDIQ 125

  Fly   263 VRPFNADKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQ 327
            |...:.....::|.|..:.|..|:.|.|::|.:|.|..:.......|..|..:.|....|..:..
Mouse   126 VMLKSDASPSSIRILKSDMMSHLVKIPGIIISASAVRAKATRISIQCRSCHNTLTNIAMRPGLEG 190

  Fly   328 PTLCTNCNTNHCFR---------LIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVD 383
            ..|...||.:...|         ::.::.:..|.|.:||||.||.:..|:.|.::.||....|.|
Mouse   191 YALPRKCNMDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCD 255

  Fly   384 KVQPGDRVTVTGIYRATPLKTGGLSSS---------VKSVYKTHVDVVHFRKVDNKRLYEDEEGK 439
            ||.||:|||:.|||   .:|..||:.|         ::|.|   :.|:        .:..|.:|.
Mouse   256 KVVPGNRVTIMGIY---SIKKFGLNPSKGRDRVGVGIRSSY---IRVL--------GIQVDTDGS 306

  Fly   440 DHIF----PPERVELLQLLAKKPDIYDRLARAIAPSIYENDDIKKGILLQLFGGTKKKHAT-LGR 499
            ...|    .|:..|..:.||..|:||:.::::|:|||:...|:||.|...||||::|:... |.|
Mouse   307 GRSFAGSVSPQEEEEFRRLAALPNIYELISKSISPSIFGGMDMKKAIACLLFGGSRKRLPDGLTR 371

  Fly   500 QNFRSEIHLLLCGDPGTSKSQMLQYVFNLVPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGA 564
               |.:|:||:.|||||:|||:|::|....|...||||:||||.||||.|.:||.:|..:::.||
Mouse   372 ---RGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVIRDPSSRNFIMEGGA 433

  Fly   565 LVLADNGVCCIDEFDKMNDSTRSVLHEVMEQQTLSIAKAGIICQLNARTSILAAANPAESQWNKR 629
            :||||.||.||||||||.:..|..:||.|||||:|||||||...||:|.|:|||||....:|::.
Mouse   434 MVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDET 498

  Fly   630 KNIIDNVQLPHTLLSRFDLIFLVLDPQDEIFDKRLASHLVSLYY--VTRHEEEDTMFDMSVLRDY 692
            |. .||:....|:|||||:||:|.|..:|..|..||.|:::|:.  :|:.:..:...|::.::.:
Mouse   499 KG-EDNIDFMPTILSRFDMIFIVKDEHNEERDMMLAKHVMTLHVSALTQTQAVEGEIDLAKMKKF 562

  Fly   693 IAYAREHLSPTLSDEAQQRLIQAYVDMRKVGA--------GRGQISAYPRQLESLIRLSEAHAKV 749
            |||.|....|.||.||.::|...|:.||. ||        .|..|....||||:::|::||.:|:
Mouse   563 IAYCRARCGPRLSAEAAEKLKNRYIIMRS-GARQHERDSDRRSSIPITVRQLEAIVRIAEALSKM 626

  Fly   750 RLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGILTTGLSTAARKKRADLVAAIKENLKKK 814
            :|.......|||||.||.:.:...:|   |||.:      :|:.....::..::::.|::.||::
Mouse   627 KLQPFATEADVEEALRLFQVSTLDAA---LSGNL------SGVEGFTTQEDQEMLSRIEKQLKRR 682

  Fly   815 GKVLTVPYQKLFSDIKEGSQIM-ITREQF-EDALKEV 849
            ..:        .|.:.|.|.:. .|:::: |.|:::|
Mouse   683 FAI--------GSQVSEHSIVQDFTKQKYPEHAIRKV 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039	4/8 (50%)
		MCM_N	165..267	CDD:464206	22/109 (20%)
		MCM	270..772	CDD:214631	199/534 (37%)
Mcm5	NP_032592.2	MCM_N	32..130	CDD:464206	22/109 (20%)
		MCM	133..649	CDD:214631	199/534 (37%)
		Arginine finger	512..515		2/2 (100%)