Protein Alignment dpa and mcm-4

DIOPT Version :10

• Sequence 1: NP_477185.1
• Gene: dpa / 35679
• FlyBaseID: FBgn0015929
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_490962.1
• Gene: mcm-4 / 171793
• WormBaseID: WBGene00003156
• Length: 823
• Species: Caenorhabditis elegans
• Alignment Length: 853
• Identity: 439/853 - (51%)
• Similarity: 575/853 - (67%)
• Gaps: 67/853 - (7%)

  Fly    34 PMRMGPGRAVRPSDNISLPPTS------------PGNISLPATSPARGL--GANMSEIDLSSPLN 84
            |....|......|.::...|:|            .||:|..:||.|..|  |:.|
 Worm     2 PRSNDPAEPQSESADLFAEPSSQHSSMRSGSEQVAGNMSPRSTSSASALQYGSEM---------- 56

  Fly    85 YGTPSSMGSIRTPRSGIRGTPLRARPDI---RTDKRIRQVAIGGGSGLEPIPEKGSETTDPVSES 146
             |:.|.|.|..|.|   ||.|   |.|:   ..|.|..|:             :|.|  |.::..
 Worm    57 -GSVSQMSSASTLR---RGGP---RGDLGIAAVDHRTVQI-------------RGME--DEMAGD 99

  Fly   147 SQAPQLVVWGTNVVVSQCKSKFKSFIMRF-IDPSAE-------QDEISENIDVNQPLYLQKLEEI 203
            ...|:|.||||.:.|:..:..|:.|:..| |...||       .||....||||.|.|:::|.|.
 Worm   100 DGQPRLYVWGTRICVADVQRSFRDFLTTFKISQLAEDENMMTGHDEALHEIDVNHPYYMERLLEC 164

  Fly   204 HTLEEPYLNLNCAHLKTFDQDLYRQLICYPQEVIPGFDMAINEMFFERYPAALLEHQIQVRPFNA 268
            :..|..::|||..||..|.:.|||::|.||.:|||..|:.:||:|.||:...|.: .|::|||||
 Worm   165 NDAEVTHINLNLKHLNAFSEALYRKVIAYPADVIPYLDIVVNEVFAERFNRTLAQ-SIELRPFNA 228

  Fly   269 DKTRNMRSLNPEDMDQLISISGMVIRSSNVIPEMREAFFSCNICSFSTTVEVDRGRINQPTLCTN 333
            .||||||.|||.|:||||:|||||.|:|::|||||..:|.|.:|:|....|||:|||.:|.:|||
 Worm   229 QKTRNMRGLNPNDVDQLITISGMVTRTSSLIPEMRSGYFQCAVCAFGIESEVDKGRIEEPVVCTN 293

  Fly   334 CNTNHCFRLIHNRSEFTDKQLVKLQESPDDMAAGQTPHNVLLYAHNDLVDKVQPGDRVTVTGIYR 398
            |:..|||:|:||||.|.|||:||||||||||.:|:|||.|.:|||..||:.||||||:|||||:|
 Worm   294 CSNTHCFQLVHNRSVFLDKQVVKLQESPDDMPSGETPHTVSVYAHGSLVESVQPGDRITVTGIFR 358

  Fly   399 ATPLKTGGLSSSVKSVYKTHVDVVHFRKVDNKRLYEDEEGKDHIFPPERVELLQLLAKKPDIYDR 463
            ||.:|......::.|||:|.:|.:||||:|..||::|   .......||::.:..|:|:|||.|.
 Worm   359 ATGMKVNPKQRALASVYRTSIDALHFRKMDTSRLHQD---NGETITEERIQQIIELSKRPDIMDA 420

  Fly   464 LARAIAPSIYENDDIKKGILLQLFGGTKKKHATLGRQNFRSEIHLLLCGDPGTSKSQMLQYVFNL 528
            ||::|||||||:||:|:|:|..|||||:|...|..:...||||::|||||||||||||||||:.|
 Worm   421 LAQSIAPSIYEHDDVKRGLLCLLFGGTRKDDETTNKTKLRSEINILLCGDPGTSKSQMLQYVYRL 485

  Fly   529 VPRSQYTSGRGSSAVGLTAYVTKDPETRQLVLQTGALVLADNGVCCIDEFDKMNDSTRSVLHEVM 593
            :||||||||:|||||||||.|::|.:|:||||||||||||||||||||||||||:|.||||||||
 Worm   486 LPRSQYTSGKGSSAVGLTASVSRDADTKQLVLQTGALVLADNGVCCIDEFDKMNESARSVLHEVM 550

  Fly   594 EQQTLSIAKAGIICQLNARTSILAAANPAESQWNKRKNIIDNVQLPHTLLSRFDLIFLVLDPQDE 658
            |||||||||||||||||||.|:||||||.:|:||:.|.|::|:.||||||||||||||::|.|||
 Worm   551 EQQTLSIAKAGIICQLNARASVLAAANPVDSKWNRNKTIVENITLPHTLLSRFDLIFLIVDAQDE 615

  Fly   659 IFDKRLASHLVSLYYVTRHEEEDT-MFDMSVLRDYIAYAREHLSPTLSDEAQQRLIQAYVDMRKV 722
            :.|:||.:||||||:.....:|.| ..||::||||||||:.::.|.||:||.|.:|:.|:.|||.
 Worm   616 MQDRRLGNHLVSLYFENDGNQEKTEHVDMNLLRDYIAYAKANIHPKLSEEASQFIIEKYLFMRKA 680

  Fly   723 GAGRGQISAYPRQLESLIRLSEAHAKVRLSNQVELLDVEEAWRLHREALKQSATDPLSGKIDVGI 787
            ||..|||:||||||||||||||||||:|||.:|.:.|||:|:.|.||||||||.||.:|::||.|
 Worm   681 GAQHGQITAYPRQLESLIRLSEAHAKIRLSQEVSVDDVEKAFTLWREALKQSAVDPSTGRVDVAI 745

  Fly   788 LTTGLSTAARKKRADLVAAIKENLK-KKGKVLTVPYQKLFSDIKEGSQIMITREQFEDALKEVQD 851
            |.:|:|.:.||....:..|:.:.|| .||.|.:   :.||..:|...: ...||.|::|:.|:..
 Worm   746 LASGMSASGRKAVEAMCEAVLKQLKTAKGFVTS---KALFHTLKSADK-TCQREVFDEAINELSK 806

  Fly   852 EGAIVVMG 859
            :.:|...|
 Worm   807 KESIARSG 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpa	NP_477185.1	PHA03307	2..>150	CDD:223039	31/132 (23%)
		MCM_N	165..267	CDD:464206	42/109 (39%)
		MCM	270..772	CDD:214631	324/502 (65%)
mcm-4	NP_490962.1	MCM_N	118..227	CDD:464206	42/109 (39%)
		MCM	230..730	CDD:475121	324/502 (65%)