Protein Alignment CG1620 and Mier1

DIOPT Version :9

• Sequence 1: NP_001260777.1
• Gene: CG1620 / 35678
• FlyBaseID: FBgn0033183
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_030109639.1
• Gene: Mier1 / 71148
• MGIID: 1918398
• Length: 626
• Species: Mus musculus
• Alignment Length: 582
• Identity: 171/582 - (29%)
• Similarity: 257/582 - (44%)
• Gaps: 150/582 - (25%)

  Fly    27 NSDLAVTPTKRERRKSPATSSDNNSTSVQPPMSPSSSVADTTFEPTIDMMVNDFDDEATLNEEEA 91
            |:.|.:...:|:.....|||.|:.                  |:|:.||:|:|||||.||.|||.
Mouse   113 NTSLLIANVRRKVSGGSATSEDHE------------------FDPSADMLVHDFDDERTLEEEEM 159

  Fly    92 LADMEAHSAEDEIATLREESEMPIEELLAKYGGTAASPAMSSSNRSGSSSRRARRATKRQYQELD 156
            :......|:  ||..|..|.:|||.|||:.||
Mouse   160 MEGETNFSS--EIEDLAREGDMPIHELLSLYG--------------------------------- 189

  Fly   157 TEMAHTSTSTSSSTSQLEKHDGIDQEEEPKEEADKLASPPESGEASSVDTEDAQKYEGIKKQHRS 221
                      ..||.:|.:.:..::|||..|:.:...:...||.:.....|:.:...|.:.:.:|
Mouse   190 ----------YDSTVRLPEEEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQS 244

  Fly   222 HLLDLYPDESFVDLAPTCGEETERFTPLQTLFDEVEAEEEEESESELD-----DARKIIMVGHDY 281
            ...|  |.:|.     |..:..|...|.:..:.:..:|.|||||.:.|     |.:|.||||..:
Mouse   245 SNDD--PSQSV-----TSQDAQEIIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMF 302

  Fly   282 QAEIPEGLSQYGD-ILPYENEDQLIWEPSQVSEREVEEYLAKIQETRSIVPPDDGSETTAGEEGA 345
            |||||.|:.:|.: ...|||:|||:|:|..:.|.:|..:|            .|.|..|..|:|
Mouse   303 QAEIPVGVCRYKENEKVYENDDQLLWDPECLPEEKVVVFL------------KDASRRTGDEKG- 354

  Fly   346 ATGATIEPPAPITAPATPPRAPLATSGAGDQELVVKDNEQALHLLVQCGYDFKEALRRKRMNVLP 410
                         ..|.|..:.            :|||||||:.||:|.:|.:|||||.|.||..
Mouse   355 -------------VEAIPEGSH------------IKDNEQALYELVKCSFDTEEALRRLRFNVKA 394

  Fly   411 LTDTMSSWSEDECLKFEEGIQRFGKDFYQIRQNQVRTRTMRELVHFYYLWKKSERRD-------- 467
            ..:.:|.|:|:||..||:|::.:||||:.|:.|:||||::.|.|.|||:||||||.|
Mouse   395 AREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRF 459

  Fly   468 --QSFALNDTI-DHMDVFINEAGGGNGSGNGNGAGIVSGTANS-----NGSCSPHSSNG-HSNGD 523
              :.:.|:..: |:||..::|:.....|...:.....|.::||     :|:.|..:.|| .|||.
Mouse   460 GKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSNSQSEKEDGAVSSRNQNGVSSNGP 524

  Fly   524 LSALEKDTIASPRKPASKSYSIMTGSQAVGNPSGGNRKRCSSASLPLEDEDNNVEEEPSLST 585
            ...|.|:             .:......|..|:|||:|..      |.|.|.|..|..:|:|
Mouse   525 GEILNKE-------------EVKVEGLHVNGPTGGNKKPL------LTDMDTNGYEANNLTT 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_001260777.1	ELM2	275..320	CDD:279754	21/45 (47%)
		SANT	417..463	CDD:197842	24/45 (53%)
		SANT_MTA3_like	417..462	CDD:212559	23/44 (52%)
Mier1	XP_030109639.1	ELM2	296..346	CDD:366648	23/61 (38%)
		SANT_MTA3_like	402..446	CDD:212559	23/43 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838072
Domainoid	1	1.000	70	1.000	Domainoid score	I9511
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I3789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001261
OrthoInspector	1	1.000	-	-		otm42538
orthoMCL	1	0.900	-	-		OOG6_107398
Panther	1	1.100	-	-	LDO	PTHR10865
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3763
SonicParanoid	1	1.000	-	-		X1119
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.780