Protein Alignment CG1620 and Mier2

DIOPT Version :9

• Sequence 1: NP_001260777.1
• Gene: CG1620 / 35678
• FlyBaseID: FBgn0033183
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_006514144.1
• Gene: Mier2 / 70427
• MGIID: 1917677
• Length: 563
• Species: Mus musculus
• Alignment Length: 594
• Identity: 161/594 - (27%)
• Similarity: 244/594 - (41%)
• Gaps: 160/594 - (26%)

  Fly    40 RKSPATSS------DNNSTSVQPPMSPSSSVADTTFEPTIDMMVNDFDDEATLNEEEALADMEAH 98
            |:||..:|      .....|:|.....|...||..|. ..:::..:::    |.|..|.|.....
Mouse    22 RQSPRVASCLVHSLCPREPSLQTTAVVSMGSADHQFN-LAELLTQNYN----LQEGCAEAPQCPD 81

  Fly    99 SAEDEIAT--LREESEMPIEELLAKYGGTAASPAMSSSNRSGSSSRRARRATKRQYQELDTEMAH 161
            ..|:|:..  :.:.|:||::||||.||..::.|.....:..|.::......|      ||.|
Mouse    82 KPEEELDKDFIDQSSDMPLDELLALYGYESSDPISEQESEGGDTAPALPDMT------LDKE--- 137

  Fly   162 TSTSTSSSTSQLEKH--DGIDQEEEPKEEADKLASPPESGEASSVDTEDAQKYEGIKKQHRSHLL 224
                      |:.|.  .| ::|||.:..||.|.....|.|||
Mouse   138 ----------QIAKDLLSG-EEEEETQSSADDLTPSVTSHEAS---------------------- 169

  Fly   225 DLYPDESFVDLAPTCGEETERFTPLQTLFDEVEAEEEEESESELDDARKIIMVGHDYQAEIP-EG 288
            ||:.::|           ..||...........:.:.||.....:..:|.||||..:||::. ..
Mouse   170 DLFHNQS-----------GSRFLAGDNGPGSSASSDTEEDALPANKCKKEIMVGPQFQADLNILH 223

  Fly   289 LSQYGDILPYENEDQLIWEPSQVSEREVEEYLAKIQETRSIVPPDDGSETTAGEEGAATGATIEP 353
            |:::.|.: |||||||:|.||.:.||||||:|.:..:.|        .:..||
Mouse   224 LNRHCDKI-YENEDQLLWSPSVLPEREVEEFLYRAVKRR--------WQEMAG------------ 267

  Fly   354 PAPITAPATPPRAPLATSGAGDQELVVKDNEQALHLLVQCGYDFKEALRRKRMNVLPLTDTMSSW 418
                      |:.|     .|:   ||||:||||:.||:|.::.:|||||.|.||..:.|.:.:|
Mouse   268 ----------PQIP-----EGE---VVKDSEQALYELVKCNFNVEEALRRLRFNVKVIRDGLCAW 314

  Fly   419 SEDECLKFEEGIQRFGKDFYQIRQNQVRTRTMRELVHFYYLWKKSERRDQ-------------SF 470
            ||:||..||.|.:..||:|:.|:.|:||||::.|.|.:|||||||||.|.             |.
Mouse   315 SEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQTRLGRRKFVSS 379

  Fly   471 ALNDTIDHMDVFINEAGGGNGSGNG---NGAGIVSGTANSNGSCSPHSSN---------GHSNGD 523
            ...||...:|       |.:..|:.   :.||:..|.:...|:..|.:.:         |..:.|
Mouse   380 GTTDTEQDLD-------GLDPDGHARLHSEAGVPVGESTREGTVEPLNVDIEAGGLDQPGVGSDD 437

  Fly   524 LSAL-----------EKDTIASPRKPASKSYSIMTGSQAVGNPSGGNRKRCS-SASLPLEDEDNN 576
            |.:.           |...:.|.::|.|.:.|......|...|..|...|.. ..:||
Mouse   438 LPSSEPGPRPFQQLDEPPAVPSLQQPTSLAASAELPPAAAAAPEPGTSPRLPVDLALP------- 495

  Fly   577 VEEEPSLST 585
             ||.|.:|:
Mouse   496 -EELPLVSS 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_001260777.1	ELM2	275..320	CDD:279754	24/45 (53%)
		SANT	417..463	CDD:197842	24/45 (53%)
		SANT_MTA3_like	417..462	CDD:212559	23/44 (52%)
Mier2	XP_006514144.1	ELM2	209..259	CDD:366648	25/50 (50%)
		SANT_MTA3_like	314..358	CDD:212559	23/43 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838071
Domainoid	1	1.000	70	1.000	Domainoid score	I9511
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I3789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062529at2759
OrthoFinder	1	1.000	-	-		FOG0001261
OrthoInspector	1	1.000	-	-		otm42538
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10865
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1119
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.860