DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1620 and Rcor3

DIOPT Version :9

Sequence 1:	NP_001260777.1	Gene:	CG1620 / 35678	FlyBaseID:	FBgn0033183	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_001128457.1	Gene:	Rcor3 / 684192	RGDID:	1593864	Length:	551	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	61/287 - (21%)
Similarity:	104/287 - (36%)	Gaps:	96/287 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 EEESESELDDARKII--MVGHDYQAEIPE---GLSQYGDILPYENEDQLIWEP-SQVSEREVEEY 319
            |.||....||....:  .||.:|||.|||   |.::|.|   .:|...|:|.| ..:.:.:::||
  Rat    41 EPESGCSSDDEHGDVGMRVGAEYQARIPEFDPGATKYTD---KDNGGMLVWSPYHSIPDAKLDEY 102

  Fly   320 LAKIQETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATSGAGDQELVVKDNE 384
            :|..:|..                    |..:                                |
  Rat   103 VAIAKEKH--------------------GYNV--------------------------------E 115

  Fly   385 QALHLLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKDFYQIRQNQVRTRT 449
            |||.:|....::.:::| ....|..|..|   .|:.::.:.||:.....||.|::|:| .:..:|
  Rat   116 QALGMLFWHKHNIEKSL-ADLPNFTPFPD---EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKT 175

  Fly   450 MRELVHFYYLWKKSERRDQSFALNDTIDHMDVFINEAGGGNGSGNGNGAGIVSGTANSNGSCSPH 514
            :..||.:||.|||:..|...         ||....:....:..|:           :.:....||
  Rat   176 IASLVKYYYSWKKTRSRTSL---------MDRQARKLANRHNQGD-----------SDDDVEEPH 220

  Fly   515 SSNGHSNGDLSALEKDTIASPRKPASK 541
            ..:|:          |:...|:|.|.:
  Rat   221 PMDGN----------DSDYDPKKEAKR 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_001260777.1	ELM2	275..320	CDD:279754	16/50 (32%)
		SANT	417..463	CDD:197842	15/45 (33%)
		SANT_MTA3_like	417..462	CDD:212559	14/44 (32%)
Rcor3	NP_001128457.1	ELM2	57..108	CDD:279754	18/53 (34%)
		SANT	143..189	CDD:197842	16/49 (33%)
		SANT	144..188	CDD:304392	14/44 (32%)
		SANT	345..390	CDD:197842
		Myb_DNA-binding	345..388	CDD:278669
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810