Protein Alignment CG1620 and mier1b

DIOPT Version :10

• Sequence 1: NP_610287.2
• Gene: CG1620 / 35678
• FlyBaseID: FBgn0033183
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001278272.1
• Gene: mier1b / 566167
• ZFINID: ZDB-GENE-070705-170
• Length: 494
• Species: Danio rerio
• Alignment Length: 576
• Identity: 167/576 - (28%)
• Similarity: 250/576 - (43%)
• Gaps: 152/576 - (26%)

  Fly    70 EPTI-----DMMVNDFDDEATLNEEEALADMEAHSAEDEIATLREESEMPIEELLAKYG-GTAAS 128
            ||::     :|::.|:||:.| .|:|.:.:.:|:..: ||..|.:|.||||:|||:.|| |.:.|
Zfish     3 EPSLGSSSPEMLLPDYDDDQT-PEDEEVPEGDANFGK-EIEELAKEGEMPIQELLSLYGYGGSGS 65

  Fly   129 PAMSSSNRSGSSSRRARRATKRQYQELDTEMAHTSTSTSSSTSQLEKHDGIDQEEEPKEEADKLA 193
            |                        :.|.|            .:.|..||.::|||.:||
Zfish    66 P------------------------DEDEE------------DEDEDEDGDEEEEEEEEE----- 89

  Fly   194 SPPESGEASSVDTEDAQKYEG-IKKQH------------RSHLLDLYPDESFVDLAPTCGEETER 245
              .|..||..:|.:|:.:..| :||:.            .||..|     |.......|.:....
Zfish    90 --EEEDEAEDMDNDDSSRSTGDLKKRQEDGAKVSTGIVKESHSTD-----SRACAVKACNKAELI 147

  Fly   246 FTPLQTLFDEVEAEEEEESESEL---DDARKIIMVGHDYQAEIPEGLSQYGD-ILPYENEDQLIW 306
            .|.....|...|.:||.|.:.:.   :|.:|.||||..||||.|.||.:|.: ...|||:|||:|
Zfish   148 RTKNHGYFQNNEVDEESEEDDDYIPSEDWKKEIMVGSMYQAETPSGLCKYKENEKVYENDDQLLW 212

  Fly   307 EPSQVSEREVEEYLAKIQETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATS 371
            .|..:.|..|.|:|.            |....| |||   ||....|
Zfish   213 NPQMLPENTVVEFLT------------DACRRT-GEE---TGVDAIP------------------ 243

  Fly   372 GAGDQELVVKDNEQALHLLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKD 436
             .|..   :|||||||:.||:|.::..|||||.|.||....:.:|.|:|:||..||:|::.:|||
Zfish   244 -EGSH---IKDNEQALYELVKCNFETDEALRRLRFNVKAAREELSVWTEEECRNFEQGLKAYGKD 304

  Fly   437 FYQIRQNQVRTRTMRELVHFYYLWKKSERRD----------QSFALNDTI-DHMDVFINEAGGGN 490
            |:.|:.|:||||::.:.|.|||:||||||.|          :.:.|:..: |:||..::|.....
Zfish   305 FHFIQANKVRTRSVGDCVAFYYMWKKSERYDFFAQQTRLGKRKYNLHPGVTDYMDRLLDETESTA 369

  Fly   491 GSGNGNGAGIVSG-----------TANSNGSCSPHSSNGHSNGDLSA---LEKDTIASPRKPASK 541
            .|.........|.           |:..|| .|.|||:......||:   ::.:::.:...|...
Zfish   370 SSRAATPLPAASSSSTTSQSEREETSGHNG-LSSHSSSADGIQTLSSDNEVKIESVQANGAPKHL 433

  Fly   542 SYSIMTGSQAV-------GNPSGGNRKR--CSSASLPLE------DEDNNVEEEPS 582
            .::..|.|..|       .|.:|..:.:  |.|...|.:      |....||.:||
Zfish   434 LHTDHTDSNGVKLTEIHNTNRNGAVKHQLDCQSLERPAKKCRTESDSLAQVETDPS 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_610287.2	ELM2	275..325	CDD:460214	24/50 (48%)
		SANT_MTA3_like	417..462	CDD:212559	22/44 (50%)
mier1b	NP_001278272.1	ELM2	180..230	CDD:460214	25/61 (41%)
		SANT_MTA3_like	286..330	CDD:212559	22/43 (51%)
		MIER1_3_C	340..>377	CDD:437258	6/36 (17%)