Protein Alignment CG1620 and mier1b

DIOPT Version :9

• Sequence 1: NP_001260777.1
• Gene: CG1620 / 35678
• FlyBaseID: FBgn0033183
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001278272.1
• Gene: mier1b / 566167
• ZFINID: ZDB-GENE-070705-170
• Length: 494
• Species: Danio rerio
• Alignment Length: 576
• Identity: 167/576 - (28%)
• Similarity: 250/576 - (43%)
• Gaps: 152/576 - (26%)

  Fly    70 EPTI-----DMMVNDFDDEATLNEEEALADMEAHSAEDEIATLREESEMPIEELLAKYG-GTAAS 128
            ||::     :|::.|:||:.| .|:|.:.:.:|:..: ||..|.:|.||||:|||:.|| |.:.|
Zfish     3 EPSLGSSSPEMLLPDYDDDQT-PEDEEVPEGDANFGK-EIEELAKEGEMPIQELLSLYGYGGSGS 65

  Fly   129 PAMSSSNRSGSSSRRARRATKRQYQELDTEMAHTSTSTSSSTSQLEKHDGIDQEEEPKEEADKLA 193
            |                        :.|.|            .:.|..||.::|||.:||
Zfish    66 P------------------------DEDEE------------DEDEDEDGDEEEEEEEEE----- 89

  Fly   194 SPPESGEASSVDTEDAQKYEG-IKKQH------------RSHLLDLYPDESFVDLAPTCGEETER 245
              .|..||..:|.:|:.:..| :||:.            .||..|     |.......|.:....
Zfish    90 --EEEDEAEDMDNDDSSRSTGDLKKRQEDGAKVSTGIVKESHSTD-----SRACAVKACNKAELI 147

  Fly   246 FTPLQTLFDEVEAEEEEESESEL---DDARKIIMVGHDYQAEIPEGLSQYGD-ILPYENEDQLIW 306
            .|.....|...|.:||.|.:.:.   :|.:|.||||..||||.|.||.:|.: ...|||:|||:|
Zfish   148 RTKNHGYFQNNEVDEESEEDDDYIPSEDWKKEIMVGSMYQAETPSGLCKYKENEKVYENDDQLLW 212

  Fly   307 EPSQVSEREVEEYLAKIQETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATS 371
            .|..:.|..|.|:|.            |....| |||   ||....|
Zfish   213 NPQMLPENTVVEFLT------------DACRRT-GEE---TGVDAIP------------------ 243

  Fly   372 GAGDQELVVKDNEQALHLLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKD 436
             .|..   :|||||||:.||:|.::..|||||.|.||....:.:|.|:|:||..||:|::.:|||
Zfish   244 -EGSH---IKDNEQALYELVKCNFETDEALRRLRFNVKAAREELSVWTEEECRNFEQGLKAYGKD 304

  Fly   437 FYQIRQNQVRTRTMRELVHFYYLWKKSERRD----------QSFALNDTI-DHMDVFINEAGGGN 490
            |:.|:.|:||||::.:.|.|||:||||||.|          :.:.|:..: |:||..::|.....
Zfish   305 FHFIQANKVRTRSVGDCVAFYYMWKKSERYDFFAQQTRLGKRKYNLHPGVTDYMDRLLDETESTA 369

  Fly   491 GSGNGNGAGIVSG-----------TANSNGSCSPHSSNGHSNGDLSA---LEKDTIASPRKPASK 541
            .|.........|.           |:..|| .|.|||:......||:   ::.:::.:...|...
Zfish   370 SSRAATPLPAASSSSTTSQSEREETSGHNG-LSSHSSSADGIQTLSSDNEVKIESVQANGAPKHL 433

  Fly   542 SYSIMTGSQAV-------GNPSGGNRKR--CSSASLPLE------DEDNNVEEEPS 582
            .::..|.|..|       .|.:|..:.:  |.|...|.:      |....||.:||
Zfish   434 LHTDHTDSNGVKLTEIHNTNRNGAVKHQLDCQSLERPAKKCRTESDSLAQVETDPS 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_001260777.1	ELM2	275..320	CDD:279754	23/45 (51%)
		SANT	417..463	CDD:197842	23/45 (51%)
		SANT_MTA3_like	417..462	CDD:212559	22/44 (50%)
mier1b	NP_001278272.1	ELM2	180..230	CDD:279754	25/61 (41%)
		SANT	286..331	CDD:197842	23/44 (52%)
		SANT_MTA3_like	286..330	CDD:212559	22/43 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581880
Domainoid	1	1.000	62	1.000	Domainoid score	I10305
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3854
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062529at2759
OrthoFinder	1	1.000	-	-		FOG0001261
OrthoInspector	1	1.000	-	-		otm25086
orthoMCL	1	0.900	-	-		OOG6_107398
Panther	1	1.100	-	-	LDO	PTHR10865
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3763
SonicParanoid	1	1.000	-	-		X1119
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.790