DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1620 and rcor2

DIOPT Version :9

Sequence 1:	NP_001260777.1	Gene:	CG1620 / 35678	FlyBaseID:	FBgn0033183	Length:	586	Species:	Drosophila melanogaster
Sequence 2:	NP_991201.1	Gene:	rcor2 / 402934	ZFINID:	ZDB-GENE-040426-1812	Length:	536	Species:	Danio rerio

Alignment Length:	284	Identity:	71/284 - (25%)
Similarity:	108/284 - (38%)	Gaps:	93/284 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 AEEEEESESELDDARKIIMVGHDYQAEIPE----GLSQYGDILPYENEDQLIWEP-SQVSEREVE 317
            :|||...|...:|:  :|.||.||||:|||    ..|:||:   .:....|:|.| ||||:..::
Zfish    25 SEEESSDEEHPNDS--MIRVGGDYQAQIPEFKPDCASRYGE---KDQRSMLVWSPNSQVSDAMLD 84

  Fly   318 EYLAKIQETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATSGAGDQELVVKD 382
            ||:...:|....                                                    :
Zfish    85 EYILMAKEKHGY----------------------------------------------------N 97

  Fly   383 NEQALHLLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKDFYQIRQNQVRT 447
            .||||.:|:...:|.:::| ....|..|..|   .|:.::.:.||:.....||.|::|:| .:..
Zfish    98 MEQALGMLLWHKHDVEKSL-ADLANFTPFPD---EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPD 157

  Fly   448 RTMRELVHFYYLWKKSERRD-----QSFAL---------NDTIDH------MDVFIN------EA 486
            :.:..||.:||.|||:..|.     |:..|         ||.|:.      .|..||      :.
Zfish   158 KMITSLVKYYYSWKKTRTRTSVMDRQARKLLSKREKNESNDEIEEGDPGSDSDFEINAKKESAKQ 222

  Fly   487 GGGNGSGNGNGAGIVSGTANSNGS 510
            ..|||.||..|......|...|.|
Zfish   223 NSGNGGGNEKGPSKSCLTRKENQS 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_001260777.1	ELM2	275..320	CDD:279754	21/49 (43%)
		SANT	417..463	CDD:197842	14/45 (31%)
		SANT_MTA3_like	417..462	CDD:212559	13/44 (30%)
rcor2	NP_991201.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44		7/20 (35%)
		ELM2	40..92	CDD:279754	22/54 (41%)
		SANT	127..173	CDD:197842	15/49 (31%)
		SANT	128..172	CDD:304392	13/44 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..264		17/68 (25%)
		SANT	332..377	CDD:197842
		Myb_DNA-binding	332..375	CDD:278669
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..536
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810