Protein Alignment CG1620 and Mier2

DIOPT Version :10

• Sequence 1: NP_610287.2
• Gene: CG1620 / 35678
• FlyBaseID: FBgn0033183
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_017450401.1
• Gene: Mier2 / 362841
• RGDID: 1307278
• Length: 618
• Species: Rattus norvegicus
• Alignment Length: 586
• Identity: 155/586 - (26%)
• Similarity: 232/586 - (39%)
• Gaps: 180/586 - (30%)

  Fly    57 PMSPSSSVAD------------------------TTFEPTIDMMVNDF--------DDEATLNE- 88
            |:|..:.:||                        |.|.||..:::|.|        |.:..|.|
  Rat    34 PLSSGAQLADYSSSQDCGCGTRSLHGFLPSPDWPTPFRPTPCLLLNPFTVVSMGSADHQFHLTEL 98

  Fly    89 -----------EEALADMEAHSAEDEIATLREESEMPIEELLAKYGGTAASPAMSSSNRSGSSSR 142
                       .|||...:....|.:...:.:.|:||::||||.||..::.|.....:..|.::.
  Rat    99 LTQNYSLQEGCAEALQGPDRPEEELDKDFIDQSSDMPLDELLALYGYESSEPISEQESEGGDTAP 163

  Fly   143 RARRATKRQYQELDTE-----MAHTSTST------SSSTSQLEKH--DGIDQEEEPKEEADKLAS 194
            .....|      ||..     :....|:.      |.|..|:.|.  .| ::|||.:..||.|..
  Rat   164 PLPDMT------LDKAWPFVLVLGVGTAVAILRLLSCSKEQIAKDLLSG-EEEEETQSSADDLTP 221

  Fly   195 PPESGEASSVDTEDAQKYEGIKKQHRSHLLDLYPDESFVDLAPTCGEETERFTPLQTLFDEVEAE 259
            ...|.|||                      ||:.::|           ..||...........:.
  Rat   222 SVTSHEAS----------------------DLFHNQS-----------GSRFLSGDNGPGSSASS 253

  Fly   260 EEEESESELDDARKIIMVGHDYQAEIP-EGLSQYGDILPYENEDQLIWEPSQVSEREVEEYLAKI 323
            :.||.....:..:|.||||..:||::. ..|:::.|.: |||||||:|.|:.:.||||||:|.:.
  Rat   254 DTEEDALPANKCKKEIMVGPQFQADLNILHLNRHCDKI-YENEDQLLWSPTVLPEREVEEFLYRA 317

  Fly   324 QETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATSGAGDQELVVKDNEQALH 388
            .:.|        .:..||                      |:.|     .|:   ||||:||||:
  Rat   318 VKRR--------WQEMAG----------------------PQIP-----EGE---VVKDSEQALY 344

  Fly   389 LLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKDFYQIRQNQVRTRTMREL 453
            .||:|.::.:|||||.|.||..:.|.:.:|||:||..||.|.:..||:|:.|:.|:||||::.|.
  Rat   345 ELVKCNFNVEEALRRLRFNVKVIRDGLCAWSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGEC 409

  Fly   454 VHFYYLWKKSERRDQSFALNDTIDHMDVFINEAGGGNGSGNGNGAGIVSGTANSNGSCSPHSSNG 518
            |.:|||||||||.|. ||....:                  |....:.|||.::.........:|
  Rat   410 VEYYYLWKKSERYDY-FAQQTRL------------------GRRKFVSSGTTDTEQDLDGLDPDG 455

  Fly   519 HSNGDLSALEKDTIASPRKPASKSYSIMTGSQAVGNPSGGNRKRCSSASLPLEDEDNNVEEEPSL 583
            |:.     |:.:| ..|.:|.|....           :||       ...|..|.|:....||..
  Rat   456 HAR-----LQSET-RVPVEPLSADIE-----------AGG-------LDQPGVDSDDLPSSEPGP 496

  Fly   584 S 584
            |
  Rat   497 S 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_610287.2	ELM2	275..325	CDD:460214	24/50 (48%)
		SANT_MTA3_like	417..462	CDD:212559	23/44 (52%)
Mier2	XP_017450401.1	ELM2	269..319	CDD:460214	24/50 (48%)
		SANT_MTA3_like	374..418	CDD:212559	23/43 (53%)