Protein Alignment CG1620 and mier1a

DIOPT Version :9

• Sequence 1: NP_001260777.1
• Gene: CG1620 / 35678
• FlyBaseID: FBgn0033183
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_955853.1
• Gene: mier1a / 321690
• ZFINID: ZDB-GENE-030131-409
• Length: 469
• Species: Danio rerio
• Alignment Length: 523
• Identity: 168/523 - (32%)
• Similarity: 240/523 - (45%)
• Gaps: 139/523 - (26%)

  Fly    55 QPPMSPSSSVA--------DTTFEPTIDMMVNDFDDEATLNEEEALADMEAHSAEDEIATLREES 111
            :|.:|.|.|..        |..|:|:.||:|:|||||.||.|:|.| :.|.:.. :||..|..|.
Zfish     3 EPSLSASGSEGAHAVVQDEDKDFDPSADMLVHDFDDEQTLEEQEKL-EGETNFT-NEIDDLTREG 65

  Fly   112 EMPIEELLAKYG-GTAASPAMSSSNRSGSSSRRARRATKRQYQELDTEMAHTSTSTSSSTSQL-E 174
            ||||||||..|| .:.|||                     :.:|.|.|   ...||.::.|:: |
Zfish    66 EMPIEELLKLYGYSSGASP---------------------EEEEEDVE---EEDSTENACSKVEE 106

  Fly   175 KHDGIDQEEEPKEEADKLASPPESGEASSVDTEDAQKYEGIKKQHRSHLLDLYPDESFVDLAPTC 239
            |.:..||||:  |:.......|.||..|                |.:.||             .|
Zfish   107 KPELSDQEED--EDVQSSGEEPPSGSVS----------------HSTALL-------------IC 140

  Fly   240 GEETERFTPLQTLFDEVEAEEEEESESELDDARKIIMVGHDYQAEIPEGLSQYGD-ILPYENEDQ 303
            ...:       |.||..|.|.|:|.....:|.:|.||||..||||.|.||.:|.| ...|||:||
Zfish   141 SRPS-------TYFDGYEEESEDEEYIPSEDWKKEIMVGSMYQAETPVGLCKYKDNEKVYENDDQ 198

  Fly   304 LIWEPSQVSEREVEEYLAKIQETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPL 368
            |:|.|..:.|.:|||:|.:..: ||      |.|  ||.:....|:.|
Zfish   199 LLWNPELLPEEKVEEFLTEASK-RS------GDE--AGVDAIPEGSHI----------------- 237

  Fly   369 ATSGAGDQELVVKDNEQALHLLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRF 433
                        |||||||:.|.:|.::..|||:|.:.:|.|..:.||.|:|:||..||:|::.:
Zfish   238 ------------KDNEQALYELFKCNFNADEALKRLKFDVKPAKEEMSVWTEEECRGFEQGLKDY 290

  Fly   434 GKDFYQIRQNQVRTRTMRELVHFYYLWKKSERRD----------QSFALN-DTIDHMDVFINEAG 487
            ||||..|:.|:||||::.|.|.|||:||||||.|          :.::|. ..:|:|:.|::|..
Zfish   291 GKDFSSIQANKVRTRSVEECVAFYYMWKKSERYDFFAQQIKLGKRKYSLRPGVLDYMECFLDEKE 355

  Fly   488 GGNGSGNGNGAGIVSGTANSNGSCSP-------HSSNG---HSNGDLSALEKDTIASPRKPASKS 542
            .....|:.     :|....||.|.:|       ::.||   ||:..|..::.:|..:....|...
Zfish   356 SSESGGSS-----LSLPTTSNNSKNPLEPESDSNAQNGVENHSSEPLLCVKDETSHTNGSTARPE 415

  Fly   543 YSI 545
            .||
Zfish   416 ISI 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_001260777.1	ELM2	275..320	CDD:279754	25/45 (56%)
		SANT	417..463	CDD:197842	24/45 (53%)
		SANT_MTA3_like	417..462	CDD:212559	23/44 (52%)
mier1a	NP_955853.1	ELM2	169..220	CDD:279754	26/50 (52%)
		SANT	275..320	CDD:197842	24/44 (55%)
		SANT_MTA3_like	275..319	CDD:212559	23/43 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581879
Domainoid	1	1.000	62	1.000	Domainoid score	I10305
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3854
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062529at2759
OrthoFinder	1	1.000	-	-		FOG0001261
OrthoInspector	1	1.000	-	-		otm25086
orthoMCL	1	0.900	-	-		OOG6_107398
Panther	1	1.100	-	-	O	PTHR10865
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1119
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.760