Protein Alignment CG1620 and Mier3

DIOPT Version :9

• Sequence 1: NP_001260777.1
• Gene: CG1620 / 35678
• FlyBaseID: FBgn0033183
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_006231987.2
• Gene: Mier3 / 310086
• RGDID: 1311241
• Length: 704
• Species: Rattus norvegicus
• Alignment Length: 590
• Identity: 174/590 - (29%)
• Similarity: 256/590 - (43%)
• Gaps: 155/590 - (26%)

  Fly    14 SASEASADSGSLANS-DLAVTPTKRERRKSPATSSDNNSTSVQPPMSPSSSVADTTFEPTIDMMV 77
            :|:.|:|..||.|.| |.|       ||.|.|..:...|:|   |:...|| .|..|:||.:|:|
  Rat   133 AAAAAAAAIGSGAPSGDWA-------RRCSFALKASFGSSS---PVGSLSS-EDHDFDPTAEMLV 186

  Fly    78 NDFDDEATLNEEEALADMEAHSAEDEIATLREESEMPIEELLAKYGGTAASPAMSSSNRSGSSSR 142
            :|:|||.||.|||.:.|.:..|:  ||..|.:|..||:|:|||.||..:..|.:::|:.:.|.|
  Rat   187 HDYDDERTLEEEELMGDGKNFSS--EIEDLEKEGNMPLEDLLAFYGYESTIPTVANSSANSSPS- 248

  Fly   143 RARRATKRQYQELDTEMAHTSTSTSSSTSQLEKHDGIDQEEEPKEEADKLASPPESGEASSVDTE 207
                       ||..|:...:.........|...|    :||.:..||.|.....|.|.|
  Rat   249 -----------ELADELPDMTLDKEEIAKDLLSGD----DEETQSSADDLTPSVTSHETS----- 293

  Fly   208 DAQKYEGIKKQHRSHLLDLYPDESFVDLAP-----TCGEETERFTPLQTLFDEVEAEEEEESESE 267
                             |.:|       .|     ||..:.|         .|:| :.|.:|.:.
  Rat   294 -----------------DFFP-------RPLRSNTTCDGDKE---------SEIE-DVETDSGNS 324

  Fly   268 LDDARKIIMVGHDYQAEIPEGLSQY-GDILPYENEDQLIWEPSQVSEREVEEYLAKIQETRSIVP 331
            .:|.||.||:|..||||||..|.:| ||...|||||||:|.|..|.|.:|:|||.:
  Rat   325 PEDLRKEIMIGLQYQAEIPPYLGEYSGDEKAYENEDQLLWRPDVVLESKVKEYLIE--------- 380

  Fly   332 PDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATSGAGDQELVVKDNEQALHLLVQCGYD 396
                                      |:..|.....|....:|..   .:||||||:.|::|.::
  Rat   381 --------------------------TSLRTGNEKVLDRISSGTH---TRDNEQALYELLKCNHN 416

  Fly   397 FKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKDFYQIRQNQVRTRTMRELVHFYYLWK 461
            ..||:.|...|.....:.|::|:|:||..||..:..:||||:.|::|:||:||:.|.|.|||:||
  Rat   417 VTEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLYGKDFHLIQKNKVRSRTVAECVAFYYMWK 481

  Fly   462 KSERRDQSFALN------------DTIDHMDVFINEAGGGNGSGNGNGAGIVSGTANSNGSCSP- 513
            ||||.|. ||..            ...|:||..::|.   ...|:     .||.:|.::....|
  Rat   482 KSERYDY-FAQQTKFGKKRYNHHPGVTDYMDRLVDET---ESLGD-----TVSSSALTSNRPEPI 537

  Fly   514 -----HSSNGHSNGDLSALEKD--TIASPRKPA--SKSYSIMTGSQAVGNPSGGNRKRCSSASLP 569
                 :..:..:..||:||...  |:.:|...:  ..|:|.:           ||..|.....:|
  Rat   538 PDQPLNILSSFTASDLTALTNSVATVCNPTDVSCLDDSFSPL-----------GNAPRGQVNHVP 591

  Fly   570 LEDED 574
            :..|:
  Rat   592 VVTEE 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_001260777.1	ELM2	275..320	CDD:279754	26/45 (58%)
		SANT	417..463	CDD:197842	23/45 (51%)
		SANT_MTA3_like	417..462	CDD:212559	22/44 (50%)
Mier3	XP_006231987.2	ELM2	332..380	CDD:279754	28/47 (60%)
		SANT	436..483	CDD:197842	23/46 (50%)
		SANT_MTA3_like	438..482	CDD:212559	22/43 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341849
Domainoid	1	1.000	72	1.000	Domainoid score	I9104
eggNOG	1	0.900	-	-		E1_KOG1194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I3723
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062529at2759
OrthoFinder	1	1.000	-	-		FOG0001261
OrthoInspector	1	1.000	-	-		otm44603
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10865
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1119
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.860