Protein Alignment CG1620 and Mier3

DIOPT Version :10

• Sequence 1: NP_610287.2
• Gene: CG1620 / 35678
• FlyBaseID: FBgn0033183
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_006517678.1
• Gene: Mier3 / 218613
• MGIID: 2442317
• Length: 597
• Species: Mus musculus
• Alignment Length: 573
• Identity: 165/573 - (28%)
• Similarity: 245/573 - (42%)
• Gaps: 157/573 - (27%)

  Fly    34 PTKRERRKSPATSSD-------NNSTSVQP--------PMSPSSSVA--DTTFEPTIDMMVNDFD 81
            ||:....:.||.|.|       ..|.::.|        ..||..|::  |..|:||.:|:|:|:|
Mouse    16 PTRPSAIRPPAASPDRGLRGQRERSGTLYPEACEASFGSSSPVGSLSSEDHDFDPTAEMLVHDYD 80

  Fly    82 DEATLNEEEALADMEAHSAEDEIATLREESEMPIEELLAKYGGTAASPAMSSSNRSGSSSRRARR 146
            ||.||.|||.:.|.:..|:  ||..|.:|..||:|:|||.||..:..||:::|:.:.|.|
Mouse    81 DERTLEEEELMDDGKNFSS--EIEDLEKEGNMPLEDLLAFYGYESTIPAVANSSANSSPS----- 138

  Fly   147 ATKRQYQELDTEMAHTSTSTSSSTSQLEKHDGIDQEEEPKEEADKLASPPESGEASSVDTEDAQK 211
                   ||..|:...:.........|...|    :||.:..||.|.....|.|.|
Mouse   139 -------ELADELPDMTLDKEEIAKDLLSGD----DEETQSSADDLTPSVTSHETS--------- 183

  Fly   212 YEGIKKQHRSHLLDLYPDESFVDLAPTCGEETERFTPLQTLFDEVEAEEEEESESELDDARKIIM 276
             |...:..||:              .||..:.|         .|:| :.|.:|.:..:|.|:.||
Mouse   184 -EFFPRPLRSN--------------TTCDGDKE---------SEIE-DVETDSGNSPEDLRREIM 223

  Fly   277 VGHDYQAEIPEGLSQYG--DILPYENEDQLIWEPSQVSEREVEEYLAKIQETRSIVPPDDGSETT 339
            :|.:||||||..|.:|.  |...|||||||:|.|..:.|.:|:|||.:
Mouse   224 IGLEYQAEIPPYLGEYNGDDEKAYENEDQLLWHPGVLLESKVKEYLVE----------------- 271

  Fly   340 AGEEGAATGATIEPPAPITAPATPPRAPLATSGAGDQELVVKDNEQALHLLVQCGYDFKEALRRK 404
                              |:..|.....|....:|..   .:||||||:.|::|.::.|||:.|.
Mouse   272 ------------------TSLRTGNEKVLDRISSGTH---TRDNEQALYELLKCNHNIKEAIERY 315

  Fly   405 RMNVLPLTDTMSSWSEDECLKFEEGIQRFGKDFYQIRQNQVRTRTMRELVHFYYLWKKSERRDQS 469
            ..|.....:.|::|:|:||..||..:...||||:.|::::||:||:.|.|.|||:||||||.|.
Mouse   316 CCNGKASQEGMTAWTEEECRSFEHALMLHGKDFHLIQKDKVRSRTVAECVAFYYMWKKSERYDY- 379

  Fly   470 FALN------------DTIDHMDVFINEAGGGNGSGNGNGAGIVSGTANSNGSCSP------HSS 516
            ||..            ...|:||..::|.....|:        ||.:|.:.....|      :..
Mouse   380 FAQQTKFGKKRYNHHPGVTDYMDRLVDETESLGGT--------VSSSALTCNRPEPVPDQPLNIL 436

  Fly   517 NGHSNGDLSALEKDTIASPRKPASKSYSIMTGSQAVGNPSGGNRKRCSSASLP 569
            :..:..||:||              :.|:.|    |.||:..|   |...|.|
Mouse   437 SSFTASDLTAL--------------TNSVAT----VCNPTAVN---CLDDSFP 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_610287.2	ELM2	275..325	CDD:460214	26/51 (51%)
		SANT_MTA3_like	417..462	CDD:212559	21/44 (48%)
Mier3	XP_006517678.1	ELM2	222..271	CDD:460214	26/48 (54%)
		SANT_MTA3_like	329..373	CDD:212559	21/43 (49%)
		MIER1_3_C	383..597	CDD:437258	22/115 (19%)