DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1620 and Rcor1

DIOPT Version :9

Sequence 1:NP_001260777.1 Gene:CG1620 / 35678 FlyBaseID:FBgn0033183 Length:586 Species:Drosophila melanogaster
Sequence 2:NP_932140.2 Gene:Rcor1 / 217864 MGIID:106340 Length:480 Species:Mus musculus


Alignment Length:381 Identity:73/381 - (19%)
Similarity:123/381 - (32%) Gaps:136/381 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   129 PAMSSSNRSGSSSRRARRATKRQYQELDTEMAHTSTSTSSSTSQLEKHDGIDQEEEPKEEADKLA 193
            |||.......|..||.|          :|..:..|.:.|::::.................|...|
Mouse     2 PAMVEKGPEVSGKRRGR----------NTAASAASAAASAASAAASAAASAGTASASAAAAASAA 56

  Fly   194 SPPESGEASSVDTEDAQKYEGIKKQHRSHLLDLYPDESFVDLAPTCGEETERFTPLQTLFDEVEA 258
            :.|.:|:                            ::|....||.....:..:            
Mouse    57 AAPNNGQ----------------------------NKSLAAAAPNGNSGSNSW------------ 81

  Fly   259 EEEEESESELDDAR--KIIMVGHDYQAEIPE-------GLSQYGDILPYENEDQLIWEPSQ-VSE 313
             ||..|.|..|:..  ..:.||..|||.:|:       ..||..|     |...|:|.|:| :||
Mouse    82 -EEGSSGSSSDEEHGGGGMRVGPQYQAAVPDFDPAKLARRSQERD-----NLGMLVWSPNQSLSE 140

  Fly   314 REVEEYLAKIQETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATSGAGDQEL 378
            .:::||:|..:|....                                                 
Mouse   141 AKLDEYIAIAKEKHGY------------------------------------------------- 156

  Fly   379 VVKDNEQALHLLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKDFYQIRQN 443
               :.||||.:|....::.:::| ....|..|..|   .|:.::.:.||:.....||.|::|:| 
Mouse   157 ---NMEQALGMLFWHKHNIEKSL-ADLPNFTPFPD---EWTVEDKVLFEQAFSFHGKTFHRIQQ- 213

  Fly   444 QVRTRTMRELVHFYYLWKKS---------ERRDQSFALNDTIDHMDVFINEAGGGN 490
            .:..:::..||.|||.|||:         ..|.|.....::.|.::    |..|.|
Mouse   214 MLPDKSIASLVKFYYSWKKTRTKTSVMDRHARKQKREREESEDELE----ETNGSN 265

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1620NP_001260777.1 ELM2 275..320 CDD:279754 17/52 (33%)
SANT 417..463 CDD:197842 15/45 (33%)
SANT_MTA3_like 417..462 CDD:212559 14/44 (32%)
Rcor1NP_932140.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..105 24/153 (16%)
Interaction with HDAC1. /evidence=ECO:0000250|UniProtKB:Q9UKL0 72..251 53/253 (21%)
ELM2 99..152 CDD:334542 19/57 (33%)
SANT 188..232 CDD:354840 14/44 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 238..308 6/32 (19%)
Interaction with KDM1A. /evidence=ECO:0000250|UniProtKB:Q9UKL0 290..378
Myb_DNA-binding 379..422 CDD:333957
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 436..466
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 41 1.000 Domainoid score I12445
eggNOG 1 0.900 - - E1_KOG1194
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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