Protein Alignment CG1620 and mier1

DIOPT Version :10

• Sequence 1: NP_610287.2
• Gene: CG1620 / 35678
• FlyBaseID: FBgn0033183
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_002939019.1
• Gene: mier1 / 100497961
• XenbaseID: XB-GENE-974218
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 549
• Identity: 166/549 - (30%)
• Similarity: 238/549 - (43%)
• Gaps: 147/549 - (26%)

  Fly    59 SPSSSVA--DTTFEPTIDMMVNDFDDEATLNEEEALADMEAHSAEDEIATLREESEMPIEELLAK 121
            ||..|.|  |..|||:.||:|::||||.||.|||.|......|:  ||..|..||||||:|||..
 Frog    10 SPGGSAASDDHEFEPSADMLVHEFDDERTLEEEEMLEGEVNFSS--EIEHLERESEMPIDELLRL 72

  Fly   122 YGGTAASPAMSSSNRSGSSSRRARRATKRQYQELDTEMAHTSTSTSSSTSQLEKHDGIDQEEEPK 186
            ||                                           ..||..|...:..::|||.:
 Frog    73 YG-------------------------------------------YGSTVPLPGEEEEEEEEEEE 94

  Fly   187 EEADKLASPPESGEASSVDTEDAQKYEGIKKQHRSHLLDLYPDESFVDLAPTCGEETERFTPLQT 251
            ||.:.:.:...||.:..:..|..:...|.:.:.:|...:..|       :.||.:..|...|.:.
 Frog    95 EEEEDVDNDGNSGCSGEIKDEAIKDSSGQEDETQSSNDEPTP-------SGTCRDVREVIRPRRC 152

  Fly   252 LFDEVEAEEEEESESELD-----DARKIIMVGHDYQAEIPEGLSQYGDI-LPYENEDQLIWEPSQ 310
            .:.:...|.|||||.:.|     |.:|.||||..:|||||.|:..|.:. ..|||:|||:|.|..
 Frog   153 KYFDANNEIEEESEDDEDYVPSEDWKKEIMVGSMFQAEIPVGICSYRETEKVYENDDQLLWNPEY 217

  Fly   311 VSEREVEEYLAKIQETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATSGAGD 375
            |.|..|.::|            ::.|..|..|:|                       |.....|.
 Frog   218 VIEDRVIDFL------------NEASRRTGEEKG-----------------------LEAIPEGS 247

  Fly   376 QELVVKDNEQALHLLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKDFYQI 440
            .   :|||||||:.||:|.:|.:|||||.|.||....:.:|.|:|:||..||:|::.:||||:.|
 Frog   248 H---IKDNEQALYELVKCNFDTEEALRRLRFNVKAAREELSIWTEEECRNFEQGLKAYGKDFHLI 309

  Fly   441 RQNQVRTRTMRELVHFYYLWKKSERRD----------QSFALNDTI-DHMDVFINEAGGGNGSGN 494
            :.|:||||::.|.|.|||:||||||.|          :.:.|:..: |:||..::|:.....|..
 Frog   310 QANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESATSSRA 374

  Fly   495 GNGAGIVSGTANS-------------------NGSCS-----PHSSNG-HSNG------DLSALE 528
            .:.....|.::.|                   ||.|:     ..:..| |.||      |.|..|
 Frog   375 PSPPPTTSNSSTSQSEKEECTASNNTQNGVSVNGPCAMTAYKDEAKQGVHLNGPTMSSSDPSPNE 439

  Fly   529 KDTIASPRKPASKSYSIMTGSQAVGNPSG 557
            .||....|:.       :||.....:.||
 Frog   440 TDTNGYNREN-------ITGDSRFSHISG 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1620	NP_610287.2	ELM2	275..325	CDD:460214	23/50 (46%)
		SANT_MTA3_like	417..462	CDD:212559	23/44 (52%)
mier1	XP_002939019.1	ELM2	181..230	CDD:460214	23/60 (38%)
		SANT_MTA3_like	287..331	CDD:212559	23/43 (53%)
		MIER1_3_C	341..>367	CDD:437258	5/25 (20%)