DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coop and CG10949

DIOPT Version :9

Sequence 1:	NP_001260776.1	Gene:	Coop / 35677	FlyBaseID:	FBgn0263240	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	60/282 - (21%)
Similarity:	111/282 - (39%)	Gaps:	62/282 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 KRLIAAVSRRPMLWLRNNANGQKR-SDITPVWFEVGQDVNLPADICRIKWGHLRDNFRKVYIRNN 104
            ::||..|...|:|:.|:.....|. :.....|.|:.:::|:..::|..:|..|||.|.:.:..:.
  Fly   139 EQLIELVKSHPVLYDRHKIRVSKNLAAKNEAWREISENLNVSEELCYNRWKKLRDRFGREFRSHQ 203

  Fly   105 LSNETPSSWRFYNDMRFM-------EPAVHENIMRQTRSSSKKHPPGHWTENNNVLGPDKYDSMP 162
            ::..||.:||::||:.|:       .|.|.|||.|:.|.....:|.|..::        :.:.|.
  Fly   204 INQSTPITWRYFNDLLFLGRHFRKGVPLVLENIKRRGRPPKAGNPSGKTSK--------QPEGMV 260

  Fly   163 IVATEPICELSHSYDSELHQPSFSDISSFFEDRDCQPPENKRFKSEPSQREEDEEDDDDFDEDAA 227
            |.:.|.|....:.|.::                                 .:|.|||.:...|..
  Fly   261 ISSGEQIWGADYPYSTD---------------------------------NDDLEDDLELAYDEE 292

  Fly   228 SENLEEERGNRADAASSGVFTIEVLDDDDEME-----QAVTKTKANNTS--HGGSSLKS-EQEAK 284
            .|.|.|     |:.|:...|.:.......::|     |..|.|.|.:..  |..:.:.. .:|:.
  Fly   293 IEILSE-----AEQATPYDFILSEATARQDLEPPQQLQVTTTTPATSEEIIHTIARVNPVVEESS 352

  Fly   285 VFSNSQSPTADLPFKYISTDVA 306
            .......|:|.:..|.::|.:|
  Fly   353 SLPGDSVPSAAISDKLLTTVIA 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coop	NP_001260776.1	MADF	42..124	CDD:214738	23/89 (26%)
Coop	NP_001260776.1	BESS	320..353	CDD:281011
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	23/85 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D98646at50557
OrthoFinder	1	1.000	-	-		FOG0009996
OrthoInspector	1	1.000	-	-		otm49873
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.020