DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p47 and PUX5

DIOPT Version :9

Sequence 1:	NP_610284.1	Gene:	p47 / 35674	FlyBaseID:	FBgn0033179	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_567463.1	Gene:	PUX5 / 827210	AraportID:	AT4G15410	Length:	421	Species:	Arabidopsis thaliana

Alignment Length:	442	Identity:	123/442 - (27%)
Similarity:	212/442 - (47%)	Gaps:	71/442 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DLIAQFIEITGTDENVARFYLSSCDWDIEHALGNYWSTQADL---------PVPVPTVGHADNP- 60
            :||..|||||.:....|.|:|.|..|:::.|:..:....|..         |.|..|:..|.:|
plant     8 NLINSFIEITSSSREEANFFLESHTWNLDAAVSTFLDNDAAAAAEPNPTGPPPPSSTIAGAQSPS 72

  Fly    61 ------------KPKPTSSSGASASASAA--------GATKSADSAVATSSASVDIAPAATKAKP 105
                        .|.|:.|..||.|:.||        ||.::.:    |.:.|...:..:.:...
plant    73 QSHSPDYTPSETSPSPSRSRSASPSSRAAPYGLRSRGGAGENKE----TENPSGIRSSRSRQHAG 133

  Fly   106 KFATLSDMSK-----ESSSDDDQQAFYAGGSDRSGQQVLGPPKRKNFREQLTDMMRSAQEQNIAE 165
            ...|.:|:::     |.|..|:...:|.|| .:||..|..|.|.|:..|......:||.::   .
plant   134 NIRTFADLNRSPADGEGSDSDEANEYYTGG-QKSGMMVQDPKKVKDVDELFDQARQSAVDR---P 194

  Fly   166 VGPSTSSGSASGGSGGAVWGQGMRLGMTDNDHTAVGTKKPAATIENKP---VVVLKLWSQGFSID 227
            |.||.|:.::..|:...:.|:.:             :..|....:.:|   :..:..|..||:::
plant   195 VEPSRSASTSFTGAARLLSGEAV-------------SSSPQQQQQEQPQRIMHTITFWLNGFTVN 246

  Fly   228 GGELRHYDDPQNKEFLETVMRGEIPQELLEMGRMVNVDVE-DHRHEDFKRQPVPQT-FKGSGQKL 290
            .|.||.:.||:|..|:.::.|.|.|.||....:.:.|.|: ..|.|:|...|.|:. |:|.|:.|
plant   247 DGPLRGFSDPENAAFMNSISRSECPSELEPADKKIPVHVDLVRRGENFTEPPKPKNPFQGVGRTL 311

  Fly   291 GS--PVANLVTEAPTVPVALSPGEAANQEASARDAINLNSEAPSTTLQIRLADGSRLAAQFNLSH 353
            |:  ..::...:|.:.|:.::|       |.:|..: ::..||:|::|:|||||:||.::||..|
plant   312 GASGSGSSSAPQASSAPMNVAP-------APSRGLV-VDPAAPTTSIQLRLADGTRLVSRFNNHH 368

  Fly   354 TVSDIRRFIQTARPQYSTSNFILVSSFPTRELSDDNSTIEKAGLKNAALMQR 405
            ||.|:|.||..:||..|....:|...||.::|::.:.|||:||:.||.::|:
plant   369 TVRDVRGFIDASRPGGSKEYQLLTMGFPPKQLTELDQTIEQAGIANAVVIQK 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p47	NP_610284.1	UBA_ceTYDP2_like	6..42	CDD:270612	13/35 (37%)
		SEP	211..300	CDD:197786	28/95 (29%)
		p47_UBX	329..407	CDD:176365	35/77 (45%)
PUX5	NP_567463.1	UBA_CF106	6..44	CDD:270534	13/35 (37%)
		SEP	231..311	CDD:197786	25/79 (32%)
		UBX_UBXN2	349..420	CDD:340468	31/70 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3144
eggNOG	1	0.900	-	-		E1_KOG2086
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41114
Inparanoid	1	1.050	159	1.000	Inparanoid score	I1647
OMA	1	1.010	-	-		QHG54012
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	1	1.000	-	-		FOG0001623
OrthoInspector	1	1.000	-	-		mtm1199
orthoMCL	1	0.900	-	-		OOG6_102041
Panther	1	1.100	-	-	O	PTHR23333
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X629
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840