Protein Alignment p47 and NSFL1C

DIOPT Version :10

• Sequence 1: NP_610284.1
• Gene: p47 / 35674
• FlyBaseID: FBgn0033179
• Length: 407
• Species: Drosophila melanogaster
• Sequence 2: XP_011527602.1
• Gene: NSFL1C / 55968
• HGNCID: 15912
• Length: 375
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 157/416 - (37%)
• Similarity: 229/416 - (55%)
• Gaps: 55/416 - (13%)

  Fly     2 AARGDLIAQFIEITGTDENVARFYLSSCDWDIEHALGNYWSTQADLPVPVPTVGHADNPKPKPTS 66
            |.|.:.:.:|:.:||.:|:.|||:|.|..||::.||.:::....|  ..:.|:..|
Human     3 AERQEALREFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGD--EDIVTISQA--------- 56

  Fly    67 SSGASASASAAGATKSADSAVATSSASVDIAPAATKAKPKFATLSDMSKESSSDDDQQ-----AF 126
                                 ..||.|...|| ..|:..:..:..|:..:...|::::     .|
Human    57 ---------------------TPSSVSRGTAP-REKSDNRVTSFRDLIHDQDEDEEEEEGQRSRF 99

  Fly   127 YAGGSDRSGQQVLGPPKRKNFREQLTDMMRSAQEQNIAEVGPSTSS-GSASGGSGGAVWGQGMRL 190
            |||||:|||||::|||::|:..|.:.|:.:.|:|.....|...|.| |..|.....|  |.|.||
Human   100 YAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFA--GGGYRL 162

  Fly   191 GMTDNDHTA--VGTKKPAATIENKPVVVLKLWSQGFSIDGGELRHYDDPQNKEFLETVMRGEIPQ 253
            |....:.:|  .|.|:..::.:..  ||||||..|||:|.||||.|.||.|.:|||::.|||:|.
Human   163 GAAPEEESAYVAGEKRQHSSQDVH--VVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPA 225

  Fly   254 EL--LEMGRMVNVDVEDHRHEDF-KRQPVPQTFKGSGQKLGSPVANLVTEAPTVPVALSPGEAAN 315
            ||  |..|..||:|:||||.||| |.:...:.|.|.||||||       .||.|....||.:.|.
Human   226 ELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGS-------TAPQVLSTSSPAQQAE 283

  Fly   316 QEASARDAINLNSEAPSTTLQIRLADGSRLAAQFNLSHTVSDIRRFIQTARPQYSTSNFILVSSF 380
            .||.|..:|.::...|:|.:|||||||.||..:||.||.:||||.||..|||..:.::|||:::|
Human   284 NEAKASSSILIDESEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTF 348

  Fly   381 PTRELSDDNSTIEKAGLKNAALMQRL 406
            |.:||:|::.|:::|.|.||.::|||
Human   349 PNKELADESQTLKEANLLNAVIVQRL 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p47	NP_610284.1	UBA_ceTYDP2_like	6..42	CDD:270612	13/35 (37%)
		SEP	211..300	CDD:197786	48/91 (53%)
		UBX_UBXN2	334..405	CDD:340468	35/70 (50%)
NSFL1C	XP_011527602.1	UBA_p47	7..45	CDD:270533	13/37 (35%)
		SEP	183..275	CDD:197786	51/100 (51%)
		UBX_UBXN2C	294..375	CDD:340682	40/81 (49%)