DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p47 and Ubxn2b

DIOPT Version :9

Sequence 1:	NP_610284.1	Gene:	p47 / 35674	FlyBaseID:	FBgn0033179	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001101375.1	Gene:	Ubxn2b / 312965	RGDID:	1308557	Length:	331	Species:	Rattus norvegicus

Alignment Length:	335	Identity:	120/335 - (35%)
Similarity:	181/335 - (54%)	Gaps:	50/335 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 PAATKAKPKFATL--SDMSKESSSDDDQQA------------FYAGGSDRSGQQVLGPPKRKNFR 148
            |:|...:...|.|  .:|..:||..|...|            .|:|..:..|..:..||..|...
  Rat    22 PSARDLQLALAELYEDEMKCKSSKPDRSTATAFKSPRTPPLRLYSGDQEYGGLHIAQPPTGKIVN 86

  Fly   149 EQLTDMMRSAQEQNIAEVGPSTSSGS---ASGGSGGAVWGQGMRLGMTDNDHTAVGTKKPAATI- 209
            |    :.:.|:|.....:..:|.|.|   |...:||     |.|||.:        ..|.:..|
  Rat    87 E----LFKEAREHGAVPLNEATRSSSDDKAKSFTGG-----GYRLGSS--------FYKRSEYIY 134

  Fly   210 -ENK---PVVVLKLWSQGFSIDGGELRHYDDPQNKEFLETVMRGEIPQEL--LEMGRMVNVDVED 268
             ||:   ..::|:|||.|||:|.||||.|.||.|.:|||:|.|||||.||  |..|..|::|:||
  Rat   135 GENQLQDVQILLRLWSNGFSLDDGELRPYSDPTNAQFLESVKRGEIPLELQRLVHGSQVSLDMED 199

  Fly   269 HRHEDFKRQPVP-QTFKGSGQKLGSPVANLVTEAPTVPVALSPGEAANQEASARDAINLNSEAPS 332
            |:.:::.:..:. :.|.|.||||||    |..|..:.|  .||.|......:|  |:.::...|:
  Rat   200 HQDQEYIKPRLRFKAFSGEGQKLGS----LTPEIVSTP--SSPEEEDKSILNA--AVLIDDSVPT 256

  Fly   333 TTLQIRLADGSRLAAQFNLSHTVSDIRRFIQTARPQYSTSNFILVSSFPTRELSDDNSTIEKAGL 397
            |.:||||||||||..:||.:|.:.|:|.||..:||:::|::||||:|||::||:|::.|::.|.:
  Rat   257 TKIQIRLADGSRLIQRFNSTHRILDVRDFIVQSRPEFATTDFILVTSFPSKELTDESVTLQDADI 321

  Fly   398 KNAALMQRLK 407
            .|..::|:||
  Rat   322 LNTVILQQLK 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p47	NP_610284.1	UBA_ceTYDP2_like	6..42	CDD:270612
		SEP	211..300	CDD:197786	44/94 (47%)
		p47_UBX	329..407	CDD:176365	36/77 (47%)
Ubxn2b	NP_001101375.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		2/3 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..63		5/24 (21%)
		SEP	140..232	CDD:197786	44/95 (46%)
		p47_UBX	253..331	CDD:176365	36/77 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336918
Domainoid	1	1.000	87	1.000	Domainoid score	I7836
eggNOG	1	0.900	-	-		E1_KOG2086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	255	1.000	Inparanoid score	I3097
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	1	1.000	-	-		FOG0001623
OrthoInspector	1	1.000	-	-		otm44527
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X629
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.760