| Sequence 1: | NP_610284.1 | Gene: | p47 / 35674 | FlyBaseID: | FBgn0033179 | Length: | 407 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_663416.1 | Gene: | Ubxn2a / 217379 | MGIID: | 2442310 | Length: | 258 | Species: | Mus musculus |
| Alignment Length: | 273 | Identity: | 84/273 - (30%) |
|---|---|---|---|
| Similarity: | 131/273 - (47%) | Gaps: | 46/273 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 153 DMMRSAQEQNIAEVGPSTSSGSASGGSGGAVWGQGMRLGMTDNDHT--------------AVGTK 203
Fly 204 KPAATIENKPV-VVLKLWSQGFSIDGGELRHYDDPQNKEFLETVMRGEIPQELLEM--GRMVNVD 265
Fly 266 VEDHRHE-DFKRQPVPQTFKGSGQKLGSPVANLVTEAPTVPVALSPGEAANQEASARDAINLNSE 329
Fly 330 APSTTLQIRLADGSRLAAQFNLSHTVSDIRRFIQTARPQYSTSNFILVSSFPTRELSDDNSTIEK 394
Fly 395 AGLKNAALMQRLK 407 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| p47 | NP_610284.1 | UBA_ceTYDP2_like | 6..42 | CDD:270612 | |
| SEP | 211..300 | CDD:197786 | 34/92 (37%) | ||
| UBX_UBXN2 | 334..405 | CDD:340468 | 26/70 (37%) | ||
| Ubxn2a | NP_663416.1 | Required for inhibition of CHRNA3 ubiquitination and translocation of CHRNA3 to the plasma membrane resulting in an increase in acetylcholine-gated nicotinic acetylcholine receptor currents. /evidence=ECO:0000269|PubMed:19474315 | 1..165 | 50/187 (27%) | |
| Required for interaction with CHRNA3. /evidence=ECO:0000250|UniProtKB:P68543 | 1..152 | 46/165 (28%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..30 | 8/42 (19%) | |||
| SEP | 66..139 | CDD:462348 | 26/73 (36%) | ||
| Required for interaction with VCP. /evidence=ECO:0000250|UniProtKB:P68543 | 168..258 | 33/82 (40%) | |||
| UBX_UBXN2A | 168..251 | CDD:340680 | 33/82 (40%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||