DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p47 and Ubxn2a

DIOPT Version :9

Sequence 1:	NP_610284.1	Gene:	p47 / 35674	FlyBaseID:	FBgn0033179	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_663416.1	Gene:	Ubxn2a / 217379	MGIID:	2442310	Length:	258	Species:	Mus musculus

Alignment Length:	273	Identity:	84/273 - (30%)
Similarity:	131/273 - (47%)	Gaps:	46/273 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 DMMRSAQEQNIAEVGPSTSSGSASGGSGGAVWGQGMRLGMTDNDHT--------------AVGTK 203
            |.:.|.:|:...|.||..|.                  .:.||...              ..|.|
Mouse     5 DNLDSIKEEWACETGPPDSQ------------------PLNDNQQKDCEYFVDSLFEEAGKAGAK 51

  Fly   204 KPAATIENKPV-VVLKLWSQGFSIDGGELRHYDDPQNKEFLETVMRGEIPQELLEM--GRMVNVD 265
            ..:.|.:.|.| |.:|||..||::: .:.|.|.|..:::||.::.:||:|.||..:  ...|:|.
Mouse    52 CLSPTEQKKQVDVNIKLWKNGFTVN-DDFRSYSDGASQQFLNSIKKGELPSELWGIFDKEEVDVK 115

  Fly   266 VEDHRHE-DFKRQPVPQTFKGSGQKLGSPVANLVTEAPTVPVALSPGEAANQEASARDAINLNSE 329
            |||.::| ....:||.|.|.|.|.:|||....:|::|.:|.|         ...|...|::||:.
Mouse   116 VEDKKNEVCMSTKPVFQPFSGQGHRLGSATPRIVSKAKSVEV---------DNKSTLSAVSLNNL 171

  Fly   330 APSTTLQIRLADGSRLAAQFNLSHTVSDIRRFIQTARPQYSTSNFILVSSFPTRELSDDNSTIEK 394
            .|.|.:||.||:|.|...:||:||.||.|:.||:..:....:..|.|.::.|.....|:..|:|:
Mouse   172 EPITRIQIWLANGERTVQRFNVSHRVSHIKDFIEKYQGSQRSPPFALATALPFLRFLDETLTLEE 236

  Fly   395 AGLKNAALMQRLK 407
            |.||||.::|||:
Mouse   237 ADLKNAVIIQRLQ 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p47	NP_610284.1	UBA_ceTYDP2_like	6..42	CDD:270612
		SEP	211..300	CDD:197786	34/92 (37%)
		p47_UBX	329..407	CDD:176365	30/77 (39%)
Ubxn2a	NP_663416.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30		8/42 (19%)
		SEP	66..138	CDD:285322	26/72 (36%)
		p47_UBX	171..249	CDD:176365	30/77 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23333
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1594
SonicParanoid	1	1.000	-	-		X629
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.910