DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p47 and ubxn-2

DIOPT Version :9

Sequence 1:	NP_610284.1	Gene:	p47 / 35674	FlyBaseID:	FBgn0033179	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001023590.1	Gene:	ubxn-2 / 177057	WormBaseID:	WBGene00022381	Length:	301	Species:	Caenorhabditis elegans

Alignment Length:	316	Identity:	90/316 - (28%)
Similarity:	137/316 - (43%)	Gaps:	63/316 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 SKESSSDDDQ----QAFYAGGSDRSGQQVLGPPKRKNFREQLTDMMRSA------QEQNIAEVGP 168
            |.:|.:|..:    |.||||    |||.|.||              |.|      .|.:|..:..
Worm    21 SDDSGADAAERGAPQEFYAG----SGQAVQGP--------------RGAAARGPDSEAHIRRILQ 67

  Fly   169 STSSGSASGGSGGAVWGQGMRLGMTDNDHTAVGTKKPAATIENKPVVVLKLWSQGFSIDGGELRH 233
            :.......||....                  |......||.    :.|.|||.|.||:.|.|..
Worm    68 AAEVVQPEGGEAPR------------------GRPSGRETIS----LTLHLWSDGLSIEDGPLMS 110

  Fly   234 YDDPQNKEFLETVMRGEIPQELLEMGRMVNVDVEDHRHEDFKRQPVPQTFKGSGQKLGSPVANLV 298
            ..||:..||||:|.:||||..|::......:|.:.:||.:....|..:.|.|||.:||:.|..::
Worm   111 RQDPRTIEFLESVGKGEIPPSLVQQYPGKEIDFKVNRHHEEYVAPKMKPFGGSGVRLGNVVPTVL 175

  Fly   299 -------TEAPTVPVAL--SPGEAANQEA----SARDAINLNSEAPSTTLQIRLADGSRLAAQFN 350
                   |.|.|.....  :|...|..||    .|:..::.|...|:|.:||||.:..||...||
Worm   176 GQSSSSATTAGTSSATTDHNPDHTAENEAKQLEDAKKELSTNMNEPTTNIQIRLPNNQRLVGIFN 240

  Fly   351 LSHTVSDIRRFIQTARPQYSTSNFILVSSFPTRELSDDNSTIEKAGLKNAALMQRL 406
            .|||:..:|.||.||||....:.|.:::::|.:...|::.|::.|.:.|:.:..::
Worm   241 HSHTLEAVRTFICTARPDMIYAPFQMMAAYPPKPFEDESQTLKDANVLNSVVAVKI 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p47	NP_610284.1	UBA_ceTYDP2_like	6..42	CDD:270612
		SEP	211..300	CDD:197786	32/95 (34%)
		p47_UBX	329..407	CDD:176365	26/78 (33%)
ubxn-2	NP_001023590.1	SEP	94..164	CDD:311829	27/69 (39%)
ubxn-2	NP_001023590.1	UBQ	220..292	CDD:320785	26/71 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I7158
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	73	1.000	Inparanoid score	I3880
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1175850at2759
OrthoFinder	1	1.000	-	-		FOG0001623
OrthoInspector	1	1.000	-	-		otm14349
orthoMCL	1	0.900	-	-		OOG6_102041
Panther	1	1.100	-	-	LDO	PTHR23333
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X629
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.970