Protein Alignment CG11141 and Tecpr2

DIOPT Version :10

• Sequence 1: NP_610282.1
• Gene: CG11141 / 35672
• FlyBaseID: FBgn0033177
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001074526.1
• Gene: Tecpr2 / 104859
• MGIID: 2144865
• Length: 1423
• Species: Mus musculus
• Alignment Length: 771
• Identity: 196/771 - (25%)
• Similarity: 310/771 - (40%)
• Gaps: 169/771 - (21%)

  Fly     1 MASSKELCSIREWAPLTEVIERIPARLQRGFFPANLNLTCVDATEEFLAMGSDAGIVFWYNRHTG 65
            |||..:..:.||:.||..::..||.::||||....:.||.:|...:::|:||..|:::.|.||..
Mouse     1 MASVSDPVTFREFCPLYYLLNAIPTKIQRGFRSIVVYLTALDTNGDYIAVGSSIGMLYLYCRHLN 65

  Fly    66 EMQKLKAE-VATRITCVRVVNSVEYMVAAGCANGQVSIFQIQKELPRDLDLVAPCTKSRPIERYT 129
            :|:|...: ....||.|::::..:.:||||.|:|:|::||:...||         .:::.:.|:.
Mouse    66 QMKKYNVDGKMESITVVKLLSCFDDLVAAGTASGRVAVFQLVSSLP---------GRNKQLRRFD 121

  Fly   130 IRDLHKCVVSCCEWSKNGMKLYSGDRQGVVVLTELDYQAHLSKSVEILSEAYEIVQLSVRQSYLL 194
            :..:||..::...||.|||||:|||.:|.:|.:.||....|..|..:|.|...||||...|..||
Mouse   122 VTGVHKTSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCSSHLVLEEPSSIVQLDYSQKVLL 186

  Fly   195 VATLYRCIVCQMDAQTSQWNITQVGKKDRKQLIDCGAIFL----KKQEANKPQLVCGRPGLRFWV 255
            |:||.|.::    ..|.:..:.|:|.:.||.....||.|:    |:.:..   |...|||||.|.
Mouse   187 VSTLQRSLL----FYTEEKAVKQIGSQPRKSTGKFGACFIPGLCKQSDLT---LYAARPGLRLWK 244

  Fly   256 ADAAGNVSKTVIFRDAVLRSPTWEIPI-LNPKQRSEPSGTHHTSASTSSTRHSGLAD--GDVGYV 317
            ||..|.|..|.|.:|......|   |. |.|  |.|||   ...:..|..:|.||..  ...|:|
Mouse   245 ADVHGTVQATYILKDVFAGGVT---PFELYP--RLEPS---DGGSCISPEKHLGLVSCFFREGWV 301

  Fly   318 ASSNFRQLYLYDGHDSLLVTHDDATLYVLNLDRLKVEAVARGLRKILDFCVCGKEIFVLEGNRTL 382
            .|.|...:||.|       |.:.||:           |...||..|:.......|||.|:|:|.:
Mouse   302 LSWNEYSIYLLD-------TVNQATV-----------AGLEGLGDIVSVSCTENEIFFLKGDRNI 348

  Fly   383 LRLAPLPEPPNKTAKVIFNPLMPP--PVPVLGSHLSQ-LESPI---ELQAEPVLQN-AEECFELS 440
            :|::..||   ..|.::.:.|...  ...|.|.||.: |.:.:   .|:...|..: |.|  :.|
Mouse   349 IRISSRPE---GIASIVRDGLEMTRCSEQVHGQHLEKSLGATVCETRLRGSSVASSVASE--QRS 408

  Fly   441 PVEQLN-------LNVP-IEIAVE-----SPLTQQNRRLEIFRRIGEMDFEQSIV---------H 483
            ....||       |.:| ::.|.|     .|.:|:      |..|...||:|.::         .
Mouse   409 RSSSLNSTDSGSGLLLPGLQAASELGQSGQPSSQR------FSVISSEDFDQELIVKPIKVKKRR 467

  Fly   484 TTRKTSVGK----PPEASGVGIVEIGHETHELRLPLTNAATLMEASYCQMENNGLASPLDMKAAF 544
            ..|||..|.    |.........|         ||..:..:| ......|.::.|.|.:|.
Mouse   468 RKRKTEGGSKSTCPSSLESTPCSE---------LPADSPQSL-NTDLLSMTSSALGSSMDQ---- 518

  Fly   545 LQHLPDALSPTTLQKTVAEKAKTLAAELD-LPEVHLAPLSQEELHAVQ--------AQTPQISD- 599
                        |.....|:...|..|:: :.:.:..|   |..|.::        |.||...:
Mouse   519 ------------LSTESPEQESNLGGEVNGISQENSGP---EAFHVLELPGPAPGPASTPTDEEN 568

  Fly   600 ----PLIRCYPTHLEEASIQTSSRENATNPADDYHVGEPVDGIRSFGVSKRKMAPLKFVLSQPKP 660
                ...:|  :|.::..:.:........|.:|....:.:.|:.                .||.|
Mouse   569 CTGKEASQC--SHTQDTDLLSGVLTLPLQPEEDVGGADIISGLD----------------EQPGP 615

  Fly   661 TLKLE---------ENRDDEEYTSFLPDFRRAGDPLAIHKETPATSDS--NTSSEW 705
            .....         :|...||..:...:|   .||.:...|.|....|  .:|..|
Mouse   616 AADAAVHTEFCLRGQNSSAEEQEADTMEF---SDPQSTFSEAPLLDSSMLPSSLSW 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11141	NP_610282.1	WD40 repeat	138..188	CDD:293791	22/49 (45%)
		WD40 repeat	194..228	CDD:293791	10/33 (30%)
Tecpr2	NP_001074526.1	WD40 repeat	37..73	CDD:293791	12/35 (34%)
		WD40 repeat	79..121	CDD:293791	15/50 (30%)
		ANAPC4_WD40	90..>151	CDD:403945	25/69 (36%)
		WD40 repeat	130..168	CDD:293791	16/37 (43%)
		WD40 repeat	175..197	CDD:293791	11/25 (44%)
		Hyd_WA	959..986	CDD:461921
		Hyd_WA	1008..1039	CDD:461921
		Tectonin	1191..1385	CDD:465992