DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Inos and MIPS3

DIOPT Version :9

Sequence 1:	NP_477405.1	Gene:	Inos / 35671	FlyBaseID:	FBgn0025885	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_196579.1	Gene:	MIPS3 / 830881	AraportID:	AT5G10170	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	509	Identity:	309/509 - (60%)
Similarity:	392/509 - (77%)	Gaps:	6/509 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TLEVISPKVQVDDEFITTDYDYQTS---HVKRTADGQLQVHPQTTSLKIRTGRHVPKLGVMLVGW 69
            :.:|.||.|:..:..|.:.|||||:   |..:....|..|.|:|...:.:|..||||||||||||
plant     5 SFKVESPNVKYTENEIHSVYDYQTTELVHENKNGAFQWTVKPKTVKYEFKTDTHVPKLGVMLVGW 69

  Fly    70 GGNNGSTLTAALEANRRQLKWRKRTGVQEANWYGSITQASTVFIGSDEDGGDVYVPMKELLPMVE 134
            ||||||||||.:.|||..:.|..:..||:||::||:||||::.:|| .:|.::|.|.|.|||||.
plant    70 GGNNGSTLTAGVIANREGISWATKEKVQQANYFGSLTQASSIRVGS-FNGEEIYAPFKSLLPMVN 133

  Fly   135 PDNIIVDGWDISGLHLGDAMRRAEVLDVALQDQIYDQLAQLRPRPSIYDPDFIAANQSDRADNVI 199
            |:.|:..|||||.::|.|||.||:|||:.||.|:...:..:.|.|.|:|||||||||..||::||
plant   134 PEEIVFGGWDISDMNLADAMARAKVLDIDLQKQMRPFMEHMVPLPGIFDPDFIAANQGSRANHVI 198

  Fly   200 RGTRLEQYEQIRKDIRDFRERSGVDSVIVLWTANTERFADVQPGLNTTSQELIASLEANHSEVSP 264
            :||:.:|.||:.||||:|:|::.||.|:|||||||||:::|..|||.|::.|::||:.:.:|:||
plant   199 KGTKKQQLEQVIKDIREFKEKNKVDKVVVLWTANTERYSNVVVGLNDTTENLMSSLDKDEAEISP 263

  Fly   265 STIFAMASIAEGCTYINGSPQNTFVPGLIQLAEEKNVFIAGDDFKSGQTKIKSVLVDFLVGAGIK 329
            ||::|:|.:.|...:||||||||||||||:||.::|..|.||||||||||:||||||||||||||
plant   264 STLYAIACVLENVPFINGSPQNTFVPGLIELAIKRNCLIGGDDFKSGQTKMKSVLVDFLVGAGIK 328

  Fly   330 PVSIASYNHLGNNDGKNLSAPQQFRSKEISKSNVVDDMVASNRLLYGPDEHPDHVVVIKYVPYVG 394
            |.||.||||||||||.||||||.||||||||||||||||.||.:||.|.|||||||||||||.||
plant   329 PTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVGSNGILYEPGEHPDHVVVIKYVPCVG 393

  Fly   395 DSKRAMDEYTSEIMMGGHNTLVIHNTCEDSLLATPLILDLVILGELSTRIQLRNAEKESAPWVPF 459
            |||||||||||||.|||.||:|:||||||||||.|:|||||:|.||:||||..:  :....:..|
plant   394 DSKRAMDEYTSEIFMGGKNTIVMHNTCEDSLLAAPIILDLVLLAELTTRIQFMS--ENEGKFHSF 456

  Fly   460 KPVLSLLSYLCKAPLVPQGSQVVNSLFRQRAAIENILRGCIGLPPISHMTLEQR 513
            .||.:|||||.||||||.|:.|||:|.:|||.:||:||.|:||.|.::|.||.:
plant   457 HPVATLLSYLSKAPLVPPGTPVVNALSKQRAMLENVLRACVGLAPENNMILEYK 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Inos	NP_477405.1	NAD_binding_5	10..513	CDD:294375	309/505 (61%)
MIPS3	NP_196579.1	PLN02438	1..510	CDD:178057	309/507 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	574	1.000	Domainoid score	I43
eggNOG	1	0.900	-	-		E1_COG1260
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6222
Inparanoid	1	1.050	621	1.000	Inparanoid score	I206
OMA	1	1.010	-	-		QHG54110
OrthoDB	1	1.010	-	-		D451916at2759
OrthoFinder	1	1.000	-	-		FOG0004516
OrthoInspector	1	1.000	-	-		otm3545
orthoMCL	1	0.900	-	-		OOG6_100830
Panther	1	1.100	-	-	O	PTHR11510
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3196
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840