DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Inos and MIPS1

DIOPT Version :9

Sequence 1:	NP_477405.1	Gene:	Inos / 35671	FlyBaseID:	FBgn0025885	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_195690.1	Gene:	MIPS1 / 830139	AraportID:	AT4G39800	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	303/508 - (59%)
Similarity:	390/508 - (76%)	Gaps:	7/508 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TLEVISPKVQVDDEFITTDYDYQTSHV--KRTADGQLQ--VHPQTTSLKIRTGRHVPKLGVMLVG 68
            :.:|.||.|:..:..|.:.|||:|:.|  ::|.:|..|  |.|:|.....:|...||||||||||
plant     5 SFKVESPNVKYTENEIHSVYDYETTEVVHEKTVNGTYQWIVKPKTVKYDFKTDIRVPKLGVMLVG 69

  Fly    69 WGGNNGSTLTAALEANRRQLKWRKRTGVQEANWYGSITQASTVFIGSDEDGGDVYVPMKELLPMV 133
            .||||||||||.:.||:..:.|..:..||:||::||:||||::.:|| .:|.::|.|.|.|||||
plant    70 LGGNNGSTLTAGVIANKEGISWATKDKVQQANYFGSLTQASSIRVGS-FNGEEIYAPFKSLLPMV 133

  Fly   134 EPDNIIVDGWDISGLHLGDAMRRAEVLDVALQDQIYDQLAQLRPRPSIYDPDFIAANQSDRADNV 198
            .||:::..|||||.::|.|||.||.|||:.||.|:...:..:.|.|.|:|||||||||..||::|
plant   134 NPDDVVFGGWDISDMNLADAMARARVLDIDLQKQLRPYMENIVPLPGIFDPDFIAANQGSRANHV 198

  Fly   199 IRGTRLEQYEQIRKDIRDFRERSGVDSVIVLWTANTERFADVQPGLNTTSQELIASLEANHSEVS 263
            |:||:.||.:.|.||:|:|:|::.||.|:|||||||||:::|..|:|.|.:.|:.|::.:.:|:|
plant   199 IKGTKKEQVDHIIKDMREFKEKNKVDKVVVLWTANTERYSNVVVGMNDTMENLMESVDRDEAEIS 263

  Fly   264 PSTIFAMASIAEGCTYINGSPQNTFVPGLIQLAEEKNVFIAGDDFKSGQTKIKSVLVDFLVGAGI 328
            |||::|:|.:.||..:||||||||||||||.:|...||.|.||||||||||:|||||||||||||
plant   264 PSTLYAIACVLEGIPFINGSPQNTFVPGLIDMAIRNNVLIGGDDFKSGQTKMKSVLVDFLVGAGI 328

  Fly   329 KPVSIASYNHLGNNDGKNLSAPQQFRSKEISKSNVVDDMVASNRLLYGPDEHPDHVVVIKYVPYV 393
            ||.||.||||||||||.||||||.|||||||||||||||||||.:|:.|.|||||||||||||||
plant   329 KPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVASNGILFEPGEHPDHVVVIKYVPYV 393

  Fly   394 GDSKRAMDEYTSEIMMGGHNTLVIHNTCEDSLLATPLILDLVILGELSTRIQLRNAEKESAPWVP 458
            .|||||||||||||.|||.||:|:||||||||||.|:|||||:|.|||||||.::  :....:..
plant   394 ADSKRAMDEYTSEIFMGGKNTIVMHNTCEDSLLAAPIILDLVLLAELSTRIQFKS--EGEGKFHS 456

  Fly   459 FKPVLSLLSYLCKAPLVPQGSQVVNSLFRQRAAIENILRGCIGLPPISHMTLE 511
            |.||.::||||.||||||.|:.|:|:|.:|||.:|||:|.|:||.|.::|.:|
plant   457 FHPVATILSYLTKAPLVPPGTPVINALSKQRAMLENIMRACVGLAPENNMIME 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Inos	NP_477405.1	NAD_binding_5	10..513	CDD:294375	303/506 (60%)
MIPS1	NP_195690.1	PLN02438	1..511	CDD:178057	303/508 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	574	1.000	Domainoid score	I43
eggNOG	1	0.900	-	-		E1_COG1260
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6222
Inparanoid	1	1.050	621	1.000	Inparanoid score	I206
OMA	1	1.010	-	-		QHG54110
OrthoDB	1	1.010	-	-		D451916at2759
OrthoFinder	1	1.000	-	-		FOG0004516
OrthoInspector	1	1.000	-	-		otm3545
orthoMCL	1	0.900	-	-		OOG6_100830
Panther	1	1.100	-	-	O	PTHR11510
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3196
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840