DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Inos and MIPS2

DIOPT Version :9

Sequence 1:	NP_477405.1	Gene:	Inos / 35671	FlyBaseID:	FBgn0025885	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_179812.1	Gene:	MIPS2 / 816757	AraportID:	AT2G22240	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	509	Identity:	312/509 - (61%)
Similarity:	392/509 - (77%)	Gaps:	6/509 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TLEVISPKVQVDDEFITTDYDYQTS---HVKRTADGQLQVHPQTTSLKIRTGRHVPKLGVMLVGW 69
            :.:|.||.|:..:..|.:.|||:|:   |..|....|..|.|:|.....:|...|||||||||||
plant     5 SFKVESPNVKYTENEINSVYDYETTEVVHENRNGTYQWVVKPKTVKYDFKTDTRVPKLGVMLVGW 69

  Fly    70 GGNNGSTLTAALEANRRQLKWRKRTGVQEANWYGSITQASTVFIGSDEDGGDVYVPMKELLPMVE 134
            ||||||||||.:.||:..:.|..:..||:||::||:||||::.:|| .:|.::|.|.|.|||||.
plant    70 GGNNGSTLTAGVIANKEGISWATKDKVQQANYFGSLTQASSIRVGS-YNGEEIYAPFKSLLPMVN 133

  Fly   135 PDNIIVDGWDISGLHLGDAMRRAEVLDVALQDQIYDQLAQLRPRPSIYDPDFIAANQSDRADNVI 199
            |::::..|||||.::|.|||.||.|||:.||.|:...:..:.|.|.|||||||||||..||::||
plant   134 PEDVVFGGWDISDMNLADAMARARVLDIDLQKQLRPYMENMIPLPGIYDPDFIAANQGSRANSVI 198

  Fly   200 RGTRLEQYEQIRKDIRDFRERSGVDSVIVLWTANTERFADVQPGLNTTSQELIASLEANHSEVSP 264
            :||:.||.:.|.||:|:|:|::.||.::|||||||||:::|..|||.|::.|:||:|.:.||:||
plant   199 KGTKKEQVDHIIKDMREFKEKNKVDKLVVLWTANTERYSNVIVGLNDTTENLLASVEKDESEISP 263

  Fly   265 STIFAMASIAEGCTYINGSPQNTFVPGLIQLAEEKNVFIAGDDFKSGQTKIKSVLVDFLVGAGIK 329
            ||::|:|.:.||..:||||||||||||||:||..||..|.||||||||||:||||||||||||||
plant   264 STLYAIACVLEGIPFINGSPQNTFVPGLIELAISKNCLIGGDDFKSGQTKMKSVLVDFLVGAGIK 328

  Fly   330 PVSIASYNHLGNNDGKNLSAPQQFRSKEISKSNVVDDMVASNRLLYGPDEHPDHVVVIKYVPYVG 394
            |.||.||||||||||.||||||.|||||||||||||||||||.:|:.|.|||||||||||||||.
plant   329 PTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVASNGILFEPGEHPDHVVVIKYVPYVA 393

  Fly   395 DSKRAMDEYTSEIMMGGHNTLVIHNTCEDSLLATPLILDLVILGELSTRIQLRNAEKESAPWVPF 459
            |||||||||||||.|||.||:|:||||||||||.|:|||||:|.|||||||.: ||.| ..:..|
plant   394 DSKRAMDEYTSEIFMGGRNTIVLHNTCEDSLLAAPIILDLVLLAELSTRIQFK-AEGE-GKFHSF 456

  Fly   460 KPVLSLLSYLCKAPLVPQGSQVVNSLFRQRAAIENILRGCIGLPPISHMTLEQR 513
            .||.::||||.||||||.|:.|||:|.:|||.:|||||.|:||.|.::|.:|.:
plant   457 HPVATILSYLTKAPLVPPGTPVVNALSKQRAMLENILRACVGLAPENNMIMEYK 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Inos	NP_477405.1	NAD_binding_5	10..513	CDD:294375	312/505 (62%)
MIPS2	NP_179812.1	PLN02438	1..510	CDD:178057	312/507 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	574	1.000	Domainoid score	I43
eggNOG	1	0.900	-	-		E1_COG1260
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6222
Inparanoid	1	1.050	621	1.000	Inparanoid score	I206
OMA	1	1.010	-	-		QHG54110
OrthoDB	1	1.010	-	-		D451916at2759
OrthoFinder	1	1.000	-	-		FOG0004516
OrthoInspector	1	1.000	-	-		otm3545
orthoMCL	1	0.900	-	-		OOG6_100830
Panther	1	1.100	-	-	LDO	PTHR11510
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3196
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840