Protein Alignment Inos and inos-1

DIOPT Version :10

• Sequence 1: NP_477405.1
• Gene: Inos / 35671
• FlyBaseID: FBgn0025885
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_496499.2
• Gene: inos-1 / 174792
• WormBaseID: WBGene00012148
• Length: 525
• Species: Caenorhabditis elegans
• Alignment Length: 505
• Identity: 265/505 - (52%)
• Similarity: 352/505 - (69%)
• Gaps: 7/505 - (1%)

  Fly     9 LEVISPKVQVDDEFITTDYDYQTSHVKRTADGQLQVHPQTTSLKIRTGRHVPKLGVMLVGWGGNN 73
            |.|.||.|:::|..:.:.:.|:.:|.:..||| |.|.|:......:|.....|.|::|||.||||
 Worm    13 LIVESPNVKLEDGVLESRFTYRKNHFEHRADG-LHVTPKEHDYSFKTVLKPRKTGLLLVGLGGNN 76

  Fly    74 GSTLTAALEANRRQLKWRKRTGVQEANWYGSITQASTVFIGSDE-DGGDVYVPMKELLPMVEPDN 137
            |||...::.||:..:.||.:.|..:||::||:||.:||.:|.|. ....::||.|:::|::.|::
 Worm    77 GSTAVGSIFANQYAMTWRTKEGHSQANYFGSVTQTATVHLGYDSATQNQIFVPFKDIVPILSPND 141

  Fly   138 IIVDGWDISGLHLGDAMRRAEVLDVALQDQIYDQLAQLRPRPSIYDPDFIAANQSDRADNVIRG- 201
            :|:.|||||..:|.:||.||:|.:..||:::...:..:.|.||||.|||||:||.|||:|||.|
 Worm   142 LIISGWDISDSNLYEAMGRAKVFEPELQEKLRPFMEPIVPLPSIYYPDFIASNQGDRANNVIPGD 206

  Fly   202 TRLEQYEQIRKDIRDFRERSGVDSVIVLWTANTERFADVQPGLNTTSQELIASLEANHSEVSPST 266
            .:||..|.||.|||.|::...::.|||||||||||:.||:.|||.|:.|::.|:..|..|||||.
 Worm   207 NKLEHLEHIRADIRKFKQEHELECVIVLWTANTERYTDVRQGLNATADEIMESIRVNEDEVSPSN 271

  Fly   267 IFAMASIAEGCTYINGSPQNTFVPGLIQLAEEKNVFIAGDDFKSGQTKIKSVLVDFLVGAGIKPV 331
            |||:|||.||..|||||||||.|||||:|||...||:.||||||||||.||..|||||.:|:||.
 Worm   272 IFAVASILEGAHYINGSPQNTLVPGLIELAERHKVFVGGDDFKSGQTKFKSAFVDFLVSSGMKPE 336

  Fly   332 SIASYNHLGNNDGKNLSAPQQFRSKEISKSNVVDDMVASNRLLYGPDEHPDHVVVIKYVPYVGDS 396
            ||.||||||||||||||..:||||||||||:||||||.||::|:...::|||.|||||||||.||
 Worm   337 SIVSYNHLGNNDGKNLSEARQFRSKEISKSSVVDDMVKSNQILFPDAKNPDHCVVIKYVPYVADS 401

  Fly   397 KRAMDEYTSEIMMGGHNTLVIHNTCEDSLLATPLILDLVILGELSTRIQLRNAEKESAPWVPFKP 461
            |||||||...|.|||..|.|:||||||||||:|||.||.||.||::|:    :.|....:.||..
 Worm   402 KRAMDEYICSIFMGGKQTFVVHNTCEDSLLASPLIYDLAILTELASRV----SYKVDDEYKPFHS 462

  Fly   462 VLSLLSYLCKAPLVPQGSQVVNSLFRQRAAIENILRGCIGLPPISHMTLE 511
            |||:||.|.|||:||.|:.:.|:..||.:.:..::....|.|..:.|.:|
 Worm   463 VLSILSLLLKAPVVPPGTPISNAFMRQFSTLTKLVTALAGFPSDTDMQIE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Inos	NP_477405.1	NAD_binding_5	10..513	CDD:469819	264/504 (52%)
inos-1	NP_496499.2	NAD_binding_5	78..494	CDD:462335	236/419 (56%)