Protein Alignment Inos and isyna1

DIOPT Version :9

• Sequence 1: NP_477405.1
• Gene: Inos / 35671
• FlyBaseID: FBgn0025885
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001119985.1
• Gene: isyna1 / 100144940
• XenbaseID: XB-GENE-969419
• Length: 564
• Species: Xenopus tropicalis
• Alignment Length: 559
• Identity: 342/559 - (61%)
• Similarity: 418/559 - (74%)
• Gaps: 22/559 - (3%)

  Fly    10 EVISPKVQVDDEFITTDYDYQTSHVKRTADGQLQVHPQTTSLKIRTGRHVPKLGVMLVGWGGNNG 74
            :|.||.|:...:.|..||:|.|:.|.. ..|..:|.|.:|.....|.|.||||||||||||||||
 Frog     6 KVESPHVRYLKDVIEADYNYDTTQVYE-EKGVTKVKPCSTKFTFHTERKVPKLGVMLVGWGGNNG 69

  Fly    75 STLTAALEANRRQLKWRKRTGVQEANWYGSITQASTVFIGSDEDGGDVYVPMKELLPMVEPDNII 139
            :|:|||:.||:..|.|..:||.:.||:|||:.|:|||.:|:. ..|:|:||.::|||||.|::|:
 Frog    70 TTVTAAVIANQLGLSWMTKTGKKVANYYGSLFQSSTVCLGTG-PAGEVFVPFRDLLPMVNPNDIV 133

  Fly   140 VDGWDISGLHLGDAMRRAEVLDVALQDQIYDQLAQLRPRPSIYDPDFIAANQSDRADNVIRGTRL 204
            .||||||.|:|.|||.||||||..||:|:...:.:::||||||.|:||||||.|||:::|.||:.
 Frog   134 FDGWDISSLNLADAMFRAEVLDWQLQEQLRPYMEKMKPRPSIYIPEFIAANQEDRANHIIHGTKA 198

  Fly   205 EQYEQIRKDIRDFRERSGVDSVIVLWTANTERFADVQPGLNTTSQELIASLEANHSEVSPSTIFA 269
            ||.::||:||:||::.|.||.||||||||||||.|:.||:|.|:..|:.::| |..||||||:||
 Frog   199 EQVQKIREDIQDFKKTSEVDKVIVLWTANTERFCDIIPGVNDTADNLLKAIE-NGLEVSPSTMFA 262

  Fly   270 MASIAEGCTYINGSPQNTFVPGLIQLAEEKNVFIAGDDFKSGQTKIKSVLVDFLVGAGIKPVSIA 334
            :|||.|.|.|||||||||||||.|:||...||||.|||||||||||||||:||||.||:|||||.
 Frog   263 VASILEDCAYINGSPQNTFVPGAIELAIRHNVFIGGDDFKSGQTKIKSVLMDFLVNAGLKPVSIV 327

  Fly   335 SYNHLGNNDGKNLSAPQQFRSKEISKSNVVDDMVASNRLLYGPDEHPDHVVVIKYVPYVGDSKRA 399
            ||||||||||||||||||||||||||||||||||.||.:||||:|.|||.|||||||||||||||
 Frog   328 SYNHLGNNDGKNLSAPQQFRSKEISKSNVVDDMVESNPILYGPNEKPDHCVVIKYVPYVGDSKRA 392

  Fly   400 MDEYTSEIMMGGHNTLVIHNTCEDSLLATPLILDLVILGELSTRIQLRNAEKESAPWVPFKPVLS 464
            ||||||||||||.||:|:||||||||||:|:|||||:|.||..||..|....:.  :..|..|||
 Frog   393 MDEYTSEIMMGGTNTIVLHNTCEDSLLASPIILDLVLLTELCQRITFRTETDQE--FQTFHSVLS 455

  Fly   465 LLSYLCKAPLVPQGSQVVNSLFRQRAAIENILRGCIGLPPISHMTLEQRFDFSTITNEPPLKRVK 529
            :||:||||||||||:.|||:|||||..||||||.|:||.|.:||.||.:...|.::    |||..
 Frog   456 ILSFLCKAPLVPQGTPVVNALFRQRNCIENILRACLGLSPQNHMMLEHKMQRSFVS----LKRPS 516

  Fly   530 ILGQPCSV-----ESVTNGKKLH----ANG--HSNGSAK 557
            .:..|..:     .:|.||  .|    :||  ||||..|
 Frog   517 TVCSPYPISIKKGNTVVNG--FHPPSISNGLSHSNGLGK 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Inos	NP_477405.1	NAD_binding_5	10..513	CDD:294375	326/502 (65%)
isyna1	NP_001119985.1	NAD_binding_5	3..504	CDD:382077	326/502 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	590	1.000	Domainoid score	I205
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H6222
Inparanoid	1	1.050	643	1.000	Inparanoid score	I802
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D240646at33208
OrthoFinder	1	1.000	-	-		FOG0004516
OrthoInspector	1	1.000	-	-		oto103624
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3196
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060